Biosystems 140:49-57 (2016)

The concepts of the origin of the genetic code and the definitions of life changed dramatically after the RNA world hypothesis. Main narratives in molecular biology and genetics such as the “central dogma,” “one gene one protein” and “non-coding DNA is junk” were falsified meanwhile. RNA moved from the transition intermediate molecule into centre stage. Additionally the abundance of empirical data concerning nonrandom genetic change operators such as the variety of mobile genetic elements, persistent viruses and defectives do not fit with the dominant narrative of error replication events (mutations) as being the main driving forces creating genetic novelty and diversity. The reductionistic and mechanistic views on physico-chemical properties of the genetic code are no longer convincing as appropriate descriptions of the abundance of non-random genetic content operators which are active in natural genetic engineering and natural genome editing.
Keywords non-coding RNAs  repeat sequences  genetic parasites  natural code users
Categories (categorize this paper)
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy

 PhilArchive page | Other versions
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

No references found.

Add more references

Citations of this work BETA

No citations found.

Add more citations

Similar books and articles

The Genetic Code and the Origin of Life.Josef Berger - 1976 - Acta Biotheoretica 25 (4):259-263.
The Paradigms of Biology.Marcello Barbieri - 2013 - Biosemiotics 6 (1):33-59.
Viruses: Essential Agents of Life.Witzany Guenther (ed.) - 2012 - Dordrecht: Springer.
The Arbitrariness of the Genetic Code.Ulrich E. Stegmann - 2004 - Biology and Philosophy 19 (2):205-222.
Human Adaptation, Biology and Society.G. A. Stepanskii - 1974 - Russian Studies in Philosophy 13 (2):107-110.
Why Take Chemistry Stoically? The Case of Posidonius.Ernesto Paparazzo - 2008 - Foundations of Chemistry 10 (1):63-75.
Noncoding RNAs: Persistent Viral Agents as Modular Tools for Cellular Needs.Witzany Guenther - 2009 - Annals of the New York Academy of Sciences 1178:244-267.


Added to PP index

Total views
592 ( #11,694 of 2,448,729 )

Recent downloads (6 months)
70 ( #8,837 of 2,448,729 )

How can I increase my downloads?


My notes