Bioessays 38 (11):1158-1166 (2016)

Abstract
The germ track is the cellular path by which genes are transmitted to future generations whereas somatic cells die with their body and do not leave direct descendants. Transposable elements (TEs) evolve to be silent in somatic cells but active in the germ track. Thus, the performance of most bodily functions by a sequestered soma reduces organismal costs of TEs. Flexible forms of gene regulation are permissible in the soma because of the self‐imposed silence of TEs, but strict licensing of transcription and translation is maintained in the germ track to control proliferation of TEs. Delayed zygotic genome activation (ZGA) and maternally inherited germ granules are adaptations that enhance germ‐track security. Mammalian embryos exhibit very early ZGA associated with extensive mobilization of retroelements. This window of vulnerability to retrotransposition in early embryos is an indirect consequence of evolutionary conflicts within the mammalian genome over postzygotic maternal provisioning.
Keywords No keywords specified (fix it)
Categories (categorize this paper)
DOI 10.1002/bies.201600125
Options
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy


Upload a copy of this paper     Check publisher's policy     Papers currently archived: 61,025
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

Sameness, Novelty, and Nominal Kinds.David Haig - 2015 - Biology and Philosophy 30 (6):857-872.

Add more references

Citations of this work BETA

Typology and Natural Kinds in Evo-Devo.Ingo Brigandt - 2021 - In Laura Nuño De La Rosa & Gerd Müller (eds.), Evolutionary Developmental Biology: A Reference Guide. Cham: Springer. pp. 483-493.

Add more citations

Similar books and articles

Playing for the Same Team Again.Matthew Slater & Achille C. Varzi - 2007 - In Jerry L. Walls & Gregory Bassham (eds.), Basketball and Philosophy. Thinking Outside the Paint. University of Kentucky Press. pp. 220–234.
Plant Transposable Elements.Hans-Peter Döring - 1985 - Bioessays 3 (4):164-171.
Maize Transposable Elements.Nina V. Fedoroff - 1991 - Perspectives in Biology and Medicine 35 (1):2-19.
Team Players.Dan Callahan - 1993 - Business Ethics 7 (3):16-16.

Analytics

Added to PP index
2017-03-26

Total views
4 ( #1,229,352 of 2,439,471 )

Recent downloads (6 months)
1 ( #433,243 of 2,439,471 )

How can I increase my downloads?

Downloads

My notes