Does the form of akinetic mutism linked to mesodiencephalic injuries bridge the double dissociation of Parkinson's disease and catatonia?
Behavioral and Brain Sciences 25 (5):586-587 (2002)
Northoff provides a compelling argument supporting a kind of “double dissociation” of Parkinson's disease and catatonia. We discuss a related form of akinetic mutism linked to mesodiencephalic injuries and suggest an alternative to the proposed “horizontal” versus “vertical” modulation distinction. Rather than a “directional” difference in patterned neuronal activity, we propose that both disorders reflect hypersynchrony within typically interdependent but segregated networks facilitated by a common thalamic gating mechanism.
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