Abstract
Equipoise is an essential condition to justify a clinical trial. The term, describes a state of uncertainty: the data suggest but do not prove a drug's safety and efficacy The only way to resolve this uncertainty is further study In many cases, a clinical trial seems to be the most efficient way to prove safety and efficacy Equipoise is therefore not an esoteric philosophic construct applied to research ethics. Rather, since it is vital for the justification of clinical trials, it is part of how society regulates medical progress. Where there is equipoise, drug design and development proceeds according to Food and Drug Administration and Health and Human Services regulations. When that equipoise ends, a drug is either not approved or becomes standard care.
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DOI http://dx.doi.org/10.1017/s0963180100008136
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References found in this work BETA

The Structure of Scientific Revolutions.David Bohm - 1964 - Philosophical Quarterly 14 (57):377-379.
Abandoning Informed Consent.Robert M. Veatch - 1995 - Hastings Center Report 25 (2):5-12.

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Citations of this work BETA

Weighing Risks and Benefits.Sven Ove Hansson - 2004 - Topoi 23 (2):145-152.
Valuing Risk: The Ethical Review of Clinical Trial Safety.Jonathan Kimmelman - 2004 - Kennedy Institute of Ethics Journal 14 (4):369-393.
Uncertainty and the Ethics of Clinical Trials.Sven Ove Hansson - 2006 - Theoretical Medicine and Bioethics 27 (2):149-167.

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