Directed Evolution: A Historical Exploration into an Evolutionary Experimental System of Nanobiotechnology, 1965–2006 [Book Review]

Minerva 46 (4):463-484 (2008)

Abstract
This study explores the history of nanotechnology from the perspective of protein engineering, which differs from the history of nanotechnology that has arisen from mechanical and materials engineering; it also demonstrates points of convergence between the two. Focusing on directed evolution—an experimental system of molecular biomimetics that mimics nature as an inspiration for material design—this study follows the emergence of an evolutionary experimental system from the 1960s to the present, by detailing the material culture, practices, and techniques involved. Directed evolution, as an aspect of nanobiotechnology, is also distinct from the dominant biotechnologies of the 20th century. The experimental systems of directed evolution produce new ways of thinking about molecular diversity that could affect concepts concerning both biology and life
Keywords Directed evolution  RNA world  Scanning probe microscopy  Molecular biomimetics  Nanotechnology  Molecular diversity
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DOI 10.1007/s11024-008-9108-9
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Genesis and Development of a Scientific Fact.Ludwik Fleck - 1979 - University of Chicago Press.

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