Significance, evidence, and the uncomfortable science of fMRI
Functional magnetic resonance imaging (or fMRI)1 is widely used to support hypotheses about brain function. Many find the images produced from fMRI data to be especially compelling evidence for scientific hypotheses [McCabe and Castel, 2008]. There are many problems with all of this; I want to start with two of them, and argue that they get us closer to an under-appreciated worry about many imaging experiments.
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