Causal isolation robustness analysis: the combinatorial strategy of circadian clock research

Biology and Philosophy 26 (5):773-791 (2011)

Authors
Tarja Knuuttila
University of South Carolina
Abstract
This paper distinguishes between causal isolation robustness analysis and independent determination robustness analysis and suggests that the triangulation of the results of different epistemic means or activities serves different functions in them. Circadian clock research is presented as a case of causal isolation robustness analysis: in this field researchers made use of the notion of robustness to isolate the assumed mechanism behind the circadian rhythm. However, in contrast to the earlier philosophical case studies on causal isolation robustness analysis (Weisberg and Reisman in Philos Sci 75:106–131, 2008 ; Kuorikoski et al. in Br J Philos Sci 61:541–567, 2010 ), robustness analysis in the circadian clock research did not remain in the level of mathematical modeling, but it combined it with experimentation on model organisms and a new type of model, a synthetic model
Keywords Philosophy   Evolutionary Biology   Philosophy of Biology
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DOI 10.1007/s10539-011-9279-x
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References found in this work BETA

Three Kinds of Idealization.Michael Weisberg - 2007 - Journal of Philosophy 104 (12):639-659.

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Citations of this work BETA

Modelling and Representing: An Artefactual Approach to Model-Based Representation.Tarja Knuuttila - 2011 - Studies in History and Philosophy of Science Part A 42 (2):262-271.
Basic Science Through Engineering? Synthetic Modeling and the Idea of Biology-Inspired Engineering.Tarja Knuuttila & Andrea Loettgers - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (2):158-169.
When One Model is Not Enough: Combining Epistemic Tools in Systems Biology.Sara Green - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (2):170-180.
Synthetic Biology and Genetic Causation.Gry Oftedal & Veli-Pekka Parkkinen - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (2):208-216.

View all 6 citations / Add more citations

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