Philosophy of Science 80 (5):874-885 (2013)

Authors
Tarja Knuuttila
University of Vienna
Andrea Loettgers
University of Vienna
Abstract
Recently, Bechtel and Abrahamsen have argued that mathematical models study the dynamics of mechanisms by recomposing the components and their operations into an appropriately organized system. We will study this claim through the practice of combinational modeling in circadian clock research. In combinational modeling, experiments on model organisms and mathematical/computational models are combined with a new type of model—a synthetic model. We argue that the strategy of recomposition is more complicated than what Bechtel and Abrahamsen indicate. Moreover, synthetic modeling as a kind of material recomposition strategy also points beyond the mechanistic paradigm
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DOI 10.1086/673965
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References found in this work BETA

Thinking About Mechanisms.Peter K. Machamer, Lindley Darden & Carl F. Craver - 2000 - Philosophy of Science 67 (1):1-25.
When Mechanistic Models Explain.Carl Craver - 2006 - Synthese 153 (3):355-376.
Mechanism and Biological Explanation.William Bechtel - 2011 - Philosophy of Science 78 (4):533-557.

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Citations of this work BETA

Varieties of Noise: Analogical Reasoning in Synthetic Biology.Tarja Knuuttila & Andrea Loettgers - 2014 - Studies in History and Philosophy of Science Part A 48:76-88.
Multiple Realizability as a Design Heuristic in Biological Engineering.Rami Koskinen - 2018 - European Journal for Philosophy of Science 9 (1):15.

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