Identifying Emotional Specificity in Complex Large-Scale Brain Networks

The target article is well in accordance with recent theoretical advances considering the complex large-scale brain network organization underlying emotions. Given current limitations of the methods in brain science, however, research is faced with the difficult question as to how it will be possible to elucidate the complex nonlinear interactions, the neurotransmitters involved, and the excitatory or inhibitory nature of neural processes underlying human emotion in such networks. Moreover, while investigating the network properties of neural processes underlying emotions, it is also important to keep in mind that specific brain structures, or specific brain networks, generate specific emotions. Thus, while aiming at elucidating complex large-scale brain networks of emotion, it is important to identify emotional specificity of, or within, these networks.