Effect of the Number of Patches in a Multi-patch SIRS Model with Fast Migration on the Basic Reproduction Rate

Acta Biotheoretica 56 (1-2):75-86 (2008)
We consider a two-patch epidemiological system where individuals can move from one patch to another, and local interactions between the individuals within a patch are governed by the classical SIRS model. When the time-scale associated with migration is much smaller than the time-scale associated with infection, aggregation methods can be used to simplify the initial complete model formulated as a system of ordinary differential equations. Analysis of the aggregated model then shows that the two-patch basic reproduction rate is smaller than the 1 patch one. We extend this result to a linear chain of P patches . These results are illustrated by some examples for which numerical integration of the system of ordinary differential equations is performed. Simulations of an individual based model implemented with a multi-agent system are also carried out
Keywords Philosophy   Evolutionary Biology   Philosophy of Biology
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DOI 10.1007/s10441-008-9036-y
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