Two models of models in biomedical research

Philosophical Quarterly 45 (179):141-160 (1995)
Abstract
Biomedical researchers claim there is significant biomedical information about humans which can be discovered only through experiments on intact animal systems (AMA p. 2). Although epidemiological studies, computer simulations, clinical investigation, and cell and tissue cultures have become important weapons in the biomedical scientists' arsenal, these are primarily "adjuncts to the use of animals in research" (Sigma Xi p. 76). Controlled laboratory experiments are the core of the scientific enterprise. Biomedical researchers claim these should be conducted on intact biological systems, whole animals. By observing the effects of various stimuli in non-human animals, we can form legitimate expectations about the likely effects of these stimuli in humans. Perhaps more importantly, we can understand the biomedical condition's causal mechanisms.
Keywords No keywords specified (fix it)
Categories (categorize this paper)
DOI 10.2307/2220412
Options
 Save to my reading list
Follow the author(s)
My bibliography
Export citation
Find it on Scholar
Edit this record
Mark as duplicate
Revision history
Request removal from index
Download options
Our Archive


Upload a copy of this paper     Check publisher's policy     Papers currently archived: 26,188
Through your library
References found in this work BETA

No references found.

Add more references

Citations of this work BETA
Extrapolation, Analogy, and Comparative Process Tracing.Francesco Guala - 2010 - Philosophy of Science 77 (5):1070-1082.
Util-Izing Animals.Hugh LaFollette & Niall Shanks - 1995 - Journal of Applied Philosophy 12 (1):13-25.
External Validity: Is There Still a Problem?Alexandre Marcellesi - 2015 - Philosophy of Science 82 (5):1308-1317.
The ‘Big Picture’: The Problem of Extrapolation in Basic Research.T. M. Baetu - 2016 - British Journal for the Philosophy of Science 67 (4):941-964.
Mutant Mice: Experimental Organisms as Materialised Models in Biomedicine.Lara Huber & Lara K. Keuck - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (3):385-391.

View all 6 citations / Add more citations

Similar books and articles

Monthly downloads

Added to index

2009-01-28

Total downloads

83 ( #61,124 of 2,153,834 )

Recent downloads (6 months)

5 ( #162,587 of 2,153,834 )

How can I increase my downloads?

My notes
Sign in to use this feature


Discussion
Order:
There  are no threads in this forum
Nothing in this forum yet.

Other forums