Relations among fields: Mendelian, cytological and molecular mechanisms

Abstract
Philosophers have proposed various kinds of relations between Mendelian genetics and molecular biology: reduction, replacement, explanatory extension. This paper argues that the two fields are best characterized as investigating different, serially integrated, hereditary mechanisms. The mechanisms operate at different times and contain different working entities. The working entities of the mechanisms of Mendelian heredity are chromosomes, whose movements serve to segregate alleles and independently assort genes in different linkage groups. The working entities of numerous mechanisms of molecular biology are larger and smaller segments of DNA plus related molecules. Discovery of molecular DNA mechanisms filled black boxes that were noted, but unilluminated, by Mendelian genetics
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DOI 10.1016/j.shpsc.2005.03.007
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References found in this work BETA
Thinking About Mechanisms.Peter K. Machamer, Lindley Darden & Carl F. Craver - 2000 - Philosophy of Science 67 (1):1-25.
Rethinking Mechanistic Explanation.Stuart Glennan - 2002 - Proceedings of the Philosophy of Science Association 2002 (3):S342-353.
Role Functions, Mechanisms, and Hierarchy.Carl F. Craver - 2001 - Philosophy of Science 68 (1):53-74.

View all 20 references / Add more references

Citations of this work BETA
Systems Biology and the Integration of Mechanistic Explanation and Mathematical Explanation.Ingo Brigandt - 2013 - Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):477-492.
The Concept of Mechanism in Biology.Daniel J. Nicholson - 2012 - Studies in History and Philosophy of Science Part C 43 (1):152-163.
Lineage Explanations: Explaining How Biological Mechanisms Change.Brett Calcott - 2009 - British Journal for the Philosophy of Science 60 (1):51-78.
From Molecules to Behavior and the Clinic: Integration in Chronobiology.William Bechtel - 2013 - Studies in History and Philosophy of Science Part C 44 (4):493-502.
Integrating Data to Acquire New Knowledge: Three Modes of Integration in Plant Science.Sabina Leonelli - 2013 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 44 (4):503-514.

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