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The purpose of this paper is to support the idea that pragmatism is still a productive resource for the study of health and disease. Combining the results of thermodynamic theories with evolutionism, some said that the biological structures selected by evolution are perfect to maximize the conservation of energy; as a consequence, they tend to reduce the entropy in the organism. Thus, a process can be defined as pathological if it increases the entropy, which means a diminished efficiency of the organism. .The point of view of pragmatism is useful to disprove the thesis of those who define disease only in relation to a reduced efficiency of the organism.
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