Predictive genetic testing in minors for late-onset conditions: a chronological and analytical review of the ethical arguments
Journal of Medical Ethics 38 (9):519-524 (2012)
Predictive genetic testing is now routinely offered to asymptomatic adults at risk for genetic disease. However, testing of minors at risk for adult-onset conditions, where no treatment or preventive intervention exists, has evoked greater controversy and inspired a debate spanning two decades. This review aims to provide a detailed longitudinal analysis and concludes by examining the debate's current status and prospects for the future. Fifty-three relevant theoretical papers published between 1990 and December 2010 were identified, and interpretative content analysis was employed to catalogue discrete arguments within these papers. Novel conclusions were drawn from this review. While the debate's first voices were raised in opposition of testing and their arguments have retained currency over many years, arguments in favour of testing, which appeared sporadically at first, have gained momentum more recently. Most arguments on both sides are testable empirical claims, so far untested, rather than abstract ethical or philosophical positions. The dispute, therein, lies not so much in whether minors should be permitted to access predictive genetic testing but whether these empirical claims on the relative benefits or harms of testing should be assessed
|Keywords||No keywords specified (fix it)|
|Categories||categorize this paper)|
References found in this work BETA
No references found.
Citations of this work BETA
Addressing the Ethical Challenges in Genetic Testing and Sequencing of Children.Ellen Wright Clayton - 2014 - American Journal of Bioethics 14 (3):3-9.
Commercial Genetic Testing and its Governance in Chinese Society.Suli Sui & Margaret Sleeboom-Faulkner - 2015 - Minerva 53 (3):215-234.
What Ethical and Legal Principles Should Guide the Genotyping of Children as Part of a Personalised Screening Programme for Common Cancer?N. Hallowell, S. Chowdhury, A. E. Hall, P. Pharoah, H. Burton & N. Pashayan - 2014 - Journal of Medical Ethics 40 (3):163-167.
Similar books and articles
Predictive Genetic Testing for Conditions That Present in Childhood.Lainie Friedman Ross - 2002 - Kennedy Institute of Ethics Journal 12 (3):225-244.
Parental Authority, Future Autonomy, and Assessing Risks of Predictive Genetic Testing in Minors.A. Boyce & P. Borry - 2009 - Journal of Bioethical Inquiry 6 (3):379-385.
Commentary on Duncan and Delatycki, 'Predictive Genetic Testing in Young People for Adult Onset Conditions: Where is the Empirical Evidence?'.Angus Clarke - unknown
Predictive Testing in Minors: The Need for Empirical Evidence.M. B. Delatycki, C. Mand, L. Gillam & R. Duncan - 2012 - Journal of Medical Ethics 38 (9):533-534.
Commentary on Predictive Genetic Testing of Minors: By Mand Et Al.A. J. Clarke - 2012 - Journal of Medical Ethics 38 (9):527-528.
Using the Best Interests Standard to Decide Whether to Test Children for Untreatable, Late-Onset Genetic Diseases.Loretta M. Kopelman - 2007 - Journal of Medicine and Philosophy 32 (4):375 – 394.
Predictive Testing for Huntington's Disease in Adolescents: Part 2.Mariam Ghosn - 2007 - Chisholm Health Ethics Bulletin 12 (3):3.
Resolving the Impasse on Predictive Genetic Testing in Minors: Will More Evidence Be the Solution?S. P. Robertson & N. Kerruish - 2012 - Journal of Medical Ethics 38 (9):525-526.
Predictive Genetic Testing of Children for Adult-Onset Diseases and Psychological Harm.P. J. Malpas - 2008 - Journal of Medical Ethics 34 (4):275-278.
Wrestling with the Future: Should We Test Children for Adult-Onset Genetic Conditions?Cynthia B. Cohen - 1998 - Kennedy Institute of Ethics Journal 8 (2):111-130.
Future Directions in Genetic Counseling: Practical and Ethical Considerations.Barabara Biesecker - 1998 - Kennedy Institute of Ethics Journal 8 (2):145-160.
Genetic Testing of Children for Late Onset Disease.Mary Ann Sevick, Donna G. Nativio & Terrance Mcconnell - 2005 - Cambridge Quarterly of Healthcare Ethics 14 (1):47-56.
Ethics and Genetics: Susceptibility Testing in the Workplace. [REVIEW]Chris MacDonald & Bryn Williams-Jones - 2002 - Journal of Business Ethics 35 (3):235 - 241.
Commercial Genetic Testing in Mainland China: Social, Financial and Ethical Issues. [REVIEW]Suli Sui & Margaret Sleeboom-Faulkner - 2007 - Journal of Bioethical Inquiry 4 (3):229-237.
Ethical Issues in Predictive Genetic Testing: A Public Health Perspective.K. G. Fulda - 2006 - Journal of Medical Ethics 32 (3):143-147.
Added to index2012-03-09
Total downloads61 ( #86,340 of 2,171,802 )
Recent downloads (6 months)1 ( #326,702 of 2,171,802 )
How can I increase my downloads?