Journal of Bioethical Inquiry 16 (4):551-557 (2019)
AbstractCancer is the second leading cause of death in developed countries, making it a global public health problem. In this scenario, early detection is the key to successful treatment. Tissue biopsy, the current gold standard for cancer diagnosis, offers reliable results, but it is feasible only when the mass becomes detectable. On the other hand liquid biopsy, a promising experimental system, not yet implemented within clinical practice, allows early detection as its functioning relies on the analysis of body fluids. Yet, its results are less reliable if compared to those of tissue biopsy as, for instance, false positives and false negatives might occur. Despite technical features, the tradeoff between a reliable diagnosis available at a later time and a potentially less reliable diagnosis available at an early stage poses significant ethical challenges in the clinical scenario which involve, among other aspects, informed consent, communication, and patient-physician encounter.
Similar books and articles
Management of an Increasing Prostate-Specific Antigen Level After Negative Prostate Biopsy.K. Shinohara, H. Nguyen & S. Masic - unknown
Racing for Consent: A Feminist Relational Analysis of Informed Consent for Nondiagnostic Breast Cancer Research Biopsies.Skye A. Miner - 2017 - International Journal of Feminist Approaches to Bioethics 10 (2):42-60.
Comparison of Two Core Biopsy Techniques Before and After Laparoscopic Cryoablation of Small Renal Cortical Neoplasms.M. D. Truesdale, A. C. Mues, S. Sartori, C. N. Casazza, G. W. Hruby, L. R. Harik, K. M. O'Toole, K. K. Badani, A. Pérez-Lanzac & J. Landman - unknown
A Novel Method for Evaluation of Improved Survival Trend for Common Cancer: Early Detection or Improvement of Medical Care.Wei-Chu Chie, Yi-Hsin Chang & Hsiu-Hsi Chen - 2007 - Journal of Evaluation in Clinical Practice 13 (1):79-85.
Altruism in Terminal Cancer Patients and Rapid Tissue Donation Program: Does the Theory Apply? [REVIEW]Gwendolyn P. Quinn, Devin Murphy, Christie Pratt, Teresita Muñoz-Antonia, Lucy Guerra, Matthew B. Schabath, Marino E. Leon & Eric Haura - 2013 - Medicine, Health Care and Philosophy 16 (4):857-864.
Ethical and Existential Challenges Associated with a Cancer Diagnosis.J. Pascal & R. Endacott - 2010 - Journal of Medical Ethics 36 (5):279-283.
Urinary and Tissue Biomarkers in Early Detection of Upper Urothelial Tract Cancer.Ivana Pešić, Janković-Veličković Lj, Dragana Stokanović & Irena Dimov - 2007 - Facta Universitatis, Series: Linguistics and Literature 14 (2):47-52.
Ethical Issues Raised by Thyroid Cancer Overdiagnosis: A Matter for Public Health?Wendy A. Rogers, Wendy L. Craig & Vikki A. Entwistle - 2017 - Bioethics 31 (8):590-598.
Obtaining Explicit Consent for the Use of Archival Tissue Samples: Practical Issues.P. N. Furness - 2004 - Journal of Medical Ethics 30 (6):561-564.
Brain Biopsy in Neurologic Decline of Unknown Etiology.S. Magaki, T. Gardner, N. Khanlou, W. H. Yong, N. Salamon & H. V. Vinters - unknown
Extended Followup and Risk Factors for Disease Reclassification in a Large Active Surveillance Cohort for Localized Prostate Cancer.C. J. Welty, J. E. Cowan, H. Nguyen, K. Shinohara, N. Perez, K. L. Greene, J. M. Chan, M. V. Meng, J. P. Simko, M. R. Cooperberg & P. R. Carroll - unknown
Family Consent, Communication, and Advance Directives for Cancer Disclosure: A Japanese Case and Discussion.A. Akabayashi, M. D. Fetters & T. S. Elwyn - 1999 - Journal of Medical Ethics 25 (4):296-301.
The Ethical Issues of Terminal Cancer Patients.Wenhao Su - 2006 - Philosophy and Culture 33 (4):5-15.
Improving Oral Cancer Survival: The Role of Dental Providers.D. V. Messadi, P. Wilder-Smith & L. Wolinsky - unknown
Added to PP
Historical graph of downloads
Citations of this work
No citations found.
References found in this work
Cancer Clinical Trial Participants' Assessment of Risk and Benefit.Connie M. Ulrich, Sarah J. Ratcliffe, Gwenyth R. Wallen, Qiuping Zhou, Kathleen Knafl & Christine Grady - 2016 - AJOB Empirical Bioethics 7 (1):8-16.