Chromosome healing: Spontaneous and programmed de novo telomere formation by telomerase

Bioessays 18 (4):301-308 (1996)
  Copy   BIBTEX

Abstract

Telomeres are protective caps for chromosome ends that are essential for genome stability. Broken chromosomes missing a telomere will not be maintained unless the chromosome is ‘healed’ with the formation of a new telomere. Chromosome healing can be a programmed event following developmentally regulated chromosome fragmentation, or it may occur spontaneously when a chromosome is accidentally broken. In this article we discuss the consequences of telomere loss and the possible mechanisms that the enzyme telomerase employs to form telomeres de novo on broken chromosome ends.

Links

PhilArchive



    Upload a copy of this work     Papers currently archived: 92,150

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

Similar books and articles

Wisdom and the art of healing.Zbigniew Szawarski - 2004 - Medicine, Health Care and Philosophy 7 (2):185-193.
The healing code: 6 minutes to heal the source of any health, success or relationship issue.Alex Loyd - 2010 - Peoria, Ariz.: Intermedia Publishing Group. Edited by Ben Johnson & Jordan Rubin.

Analytics

Added to PP
2013-11-23

Downloads
26 (#612,956)

6 months
7 (#436,298)

Historical graph of downloads
How can I increase my downloads?