Justified deception? The single blind placebo in drug research

Journal of Medical Ethics 26 (3):188-193 (2000)
  Copy   BIBTEX

Abstract

“Run-in” and “washout” periods involving the withholding of medication are widely used in drug research trials in pursuit of both patient safety and scientific reliability. Such no-medication periods can be justified ethically provided that they are apparent to patients, who can thereby properly consent to undergoing them. Less widespread, but still common, is the practice of “single blinding” no-medication periods, concealing them from patients by means of placebo. Whilst all placebos involve a measure of concealment, their use is typically justified in drug research trials by their preserving the uncertainty generated by the random allocation of different treatments within a drug trial; and by the researchers openly declaring both the randomisation process and the chances of receiving placebo. In the single blind placebo “run-in” or “washout”, neither of these conditions is met.This paper considers three possible defences of the practice of using single blind placebo “run-ins” or “washouts” and finds them all to fail; the practice appears ethically unjustified

Links

PhilArchive



    Upload a copy of this work     Papers currently archived: 74,389

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

Similar books and articles

Single Blind Placebo in Drug Research.P. Beck - 2000 - Journal of Medical Ethics 26 (6):477-a-477.
The Concept of Placebo.Zbigniew Szawarski - 2004 - Science and Engineering Ethics 10 (1):57-64.
A Limited Defense of Clinical Placebo Deception.Adam J. Kolber - 2007 - Yale Law & Policy Review 26:75-134.
What You Don't Know Can Help You: The Ethics of Placebo Treatment.Daniel Groll - 2011 - Journal of Applied Philosophy 28 (2):188-202.
Willfully Blind for Good Reason.Deborah Hellman - 2009 - Criminal Law and Philosophy 3 (3):301-316.
Intentional Self-Deception in a Single Coherent Self.W. J. Talbott - 1995 - Philosophy and Phenomenological Research 55 (1):27-74.
Does Self-Deception Involve Intentional Biasing?W. J. Talbott - 1997 - Behavioral and Brain Sciences 20 (1):127-127.

Analytics

Added to PP
2010-08-24

Downloads
31 (#373,554)

6 months
1 (#415,900)

Historical graph of downloads
How can I increase my downloads?

Citations of this work

A Plea for Pragmatism in Clinical Research Ethics.David H. Brendel & Franklin G. Miller - 2008 - American Journal of Bioethics 8 (4):24 – 31.
The Battering of Informed Consent.M. Kottow - 2004 - Journal of Medical Ethics 30 (6):565-569.
Placebo Controls: Scientific and Ethical Issues.Charles J. Kowalski - 2002 - American Journal of Bioethics 2 (2):33 – 34.

Add more citations

References found in this work

No references found.

Add more references