Understanding pathology in the context of physiological mechanisms: the practicality of a broken-normal view

Biology and Philosophy 26 (4):603-611 (2011)
Abstract
The topic of disease mechanisms is of clinical importance, as our understanding of such mechanisms plays an important role in how we approach devising treatments for disease. In this paper, I critique an argument made by Mauro Nervi, in which he asserts that pathology is often better viewed in the context of distinct theoretical mechanisms. I use this critique as a starting point to argue that viewing pathology as a broken-normal, malfunctioning mechanism is more therapeutically practical and more relevant to clinical drug design, than creating a theoretical separation of pathology from physiology
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DOI 10.1007/s10539-011-9258-2
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References found in this work BETA
Thinking About Mechanisms.Peter K. Machamer, Lindley Darden & Carl F. Craver - 2000 - Philosophy of Science 67 (1):1-25.
Mechanisms, Malfunctions and Explanation in Medicine.Mauro Nervi - 2010 - Biology and Philosophy 25 (2):215-228.

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Citations of this work BETA
The Functional Sense of Mechanism.Justin Garson - 2013 - Philosophy of Science 80 (3):317-333.
Mechanistic Explanation in Engineering Science.Dingmar van Eck - 2015 - European Journal for Philosophy of Science 5 (3):349-375.

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