Composition, training needs and independence of ethics review committees across Africa: are the gate-keepers rising to the emerging challenges?

Journal of Medical Ethics 35 (3):189-193 (2009)

Abstract
Background: The high disease burden of Africa, the emergence of new diseases and efforts to address the 10/90 gap have led to an unprecedented increase in health research activities in Africa. Consequently, there is an increase in the volume and complexity of protocols that ethics review committees in Africa have to review. Methods: With a grant from the Bill and Melinda Gates Foundation, the African Malaria Network Trust (AMANET) undertook a survey of 31 ethics review committees (ERCs) across sub-Saharan Africa as an initial step to a comprehensive capacity-strengthening programme. The number of members per committee ranged from 3 to 21, with an average of 11. Members of 10 institutional committees were all from the institution where the committees were based, raising prima facie questions as to whether independence and objectivity could be guaranteed in the review work of such committees. Results: The majority of the committees (92%) cited scientific design of clinical trials as the area needing the most attention in terms of training, followed by determination of risks and benefits and monitoring of research. The survey showed that 38% of the ERC members did not receive any form of training. In the light of the increasing complexity and numbers of health research studies being conducted in Africa, this deficit requires immediate attention. Outcome: The survey identified areas of weakness in the operations of ERCs in Africa. Consequently, AMANET is addressing the identified needs and weaknesses through a 4-year capacity-building project
Keywords info:mesh/Clinical Trials as Topic  info:mesh/Africa South of the Sahara  Humans   Ethics Committees, Research   Committee Membership   Africa South of the Sahara   Clinical Trials as Topic  info:mesh/Humans  info:mesh/Committee Membership  info:mesh/Ethics Committees, Research
Categories (categorize this paper)
DOI 10.1136/jme.2008.025189
Options
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

Our Archive


Upload a copy of this paper     Check publisher's policy     Papers currently archived: 43,780
Through your library

References found in this work BETA

Add more references

Citations of this work BETA

View all 20 citations / Add more citations

Similar books and articles

The Role of Ethics Committees in Public Debate.Lonneke M. Poort - 2008 - International Journal of Applied Philosophy 22 (1):19-35.

Analytics

Added to PP index
2010-09-13

Total views
40 ( #210,074 of 2,264,864 )

Recent downloads (6 months)
4 ( #362,355 of 2,264,864 )

How can I increase my downloads?

Downloads

My notes

Sign in to use this feature