Biological Theory 4 (4):378-389 (2009)

Abstract
Synthetic biology is an umbrella term that covers a range of aims, approaches, and techniques. They are all brought together by common practices of analogizing, synthesizing, mechanicizing, and kludging. With a focus on kludging as the connection point between biology, engineering, and evolution, I show how synthetic biology’s successes depend on custom-built kludges and a creative, “make-it-work” attitude to the construction of biological systems. Such practices do not fit neatly, however, into synthetic biology’s celebration of rational design. Nor do they straightforwardly embody Richard Feynman’s “last blackboard” statement that without creating something it cannot be understood. Reflecting further on the relationship between synthetic construction and knowledge making gives philosophy of science new avenues of insight into scientific practice
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DOI 10.1162/BIOT_a_00006
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References found in this work BETA

Conjectures and Refutations.K. Popper - 1963 - Les Etudes Philosophiques 21 (3):431-434.
Conjectures and Refutations: The Growth of Scientific Knowledge.Mary Hesse - 1965 - Philosophical Quarterly 15 (61):372-374.

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Citations of this work BETA

Dreaming of a Universal Biology: Synthetic Biology and the Origins of Life.Massimiliano Simons - 2021 - Hyle: International Journal for Philosophy of Chemistry 27:91-116.
Scientific Perspectivism: A Philosopher of Science's Response to the Challenge of Big Data Biology.Werner Callebaut - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (1):69-80.

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