Gender and the Genome 1 (4):1-6 (2017)

Authors
Abstract
In 2015 the United Kingdom (UK) became the first nation to legalize egg and zygotic nuclear transfer procedures using mitochondrial replacement techniques (MRTs) to prevent the maternal transmission of serious mitochondrial DNA diseases to offspring. These techniques are a form of human germline genetic modification and can happen intentionally if female embryos are selected during the MRT clinical process, either through sperm selection or preimplantation genetic diagnosis (PGD). In the same year, an MRT was performed by a United States (U.S.)-based physician team. This experiment involved a cross-border effort: the MRT procedure per se was carried out in the US, and the embryo transfer in Mexico. The authors examine the ethics of MRTs from the standpoint of genetic relatedness and gender implications, in places that lack adequate laws and regulation regarding assisted reproduction. Then, we briefly examine whether MRTs can be justified as a reproductive option in the US and Mexico, after reassessing their legalization in the UK. We contend that morally inadequate and ineffective regulations regarding egg donation, PGD, and germline genetic modifications jeopardize the ethical acceptability of the implementation of MRTs, suggesting that MRTs are currently difficult to justify in the US and Mexico. In addition to relevant regulation, the initiation and appropriate use of MRTs in a country require a child-centered follow-up policy and more evidence for its safety.
Keywords No keywords specified (fix it)
Categories (categorize this paper)
Options
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy

 PhilArchive page | Other versions
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

What Is the Value of Three-Parent IVF?Tina Rulli - 2016 - Hastings Center Report 46 (4):38-47.

Add more references

Citations of this work BETA

No citations found.

Add more citations

Similar books and articles

Ethical Implications of Permitting Mitochondrial Replacement.Katarina Lee - 2016 - The National Catholic Bioethics Quarterly 16 (4):619-631.
Genetic Affinity and the Right to ‘Three-Parent IVF’.G. Owen Schaefer & Markus Labude - 2017 - Journal of Assisted Reproduction and Genetics 34 (12):1577-1580.

Analytics

Added to PP index
2018-09-10

Total views
146 ( #67,308 of 2,419,604 )

Recent downloads (6 months)
23 ( #33,788 of 2,419,604 )

How can I increase my downloads?

Downloads

My notes