Bioethics 35 (1):98-104 (2021)

Monika Piotrowska
State University of New York, Albany
New discoveries are improving the odds of human cells surviving in host animals, prompting regulatory and funding agencies to issue calls for additional layers of ethical oversight for certain types of human–animal chimeras. Of interest are research proposals involving chimeric animals with humanized brains. But what is motivating the demand for additional oversight? I locate two, not obviously compatible, motivations, each of which provides the justificatory basis for paying special attention to different sets of human–animal chimeras. Surprisingly, the sets of animals that actually get flagged for special scrutiny by research and funding guidelines do not correlate with either of the sets of animals that arise when we think about what is motivating additional oversight. What this shows is that existing research policies and funding guidelines are disconnected from their motivation: the rationale for flagging certain types of human–animal chimeras as requiring special oversight is ignored in execution.
Keywords animal welfare  human–animal chimera  public policy  research ethics
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DOI 10.1111/bioe.12797
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On Human Nature.David L. Hull - 1986 - PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1986:3-13.
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At the Edge of Humanity: Human Stem Cells, Chimeras, and Moral Status.Robert Streiffer - 2005 - Kennedy Institute of Ethics Journal 15 (4):347-370.

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