Rethinking the History of Peptic Ulcer Disease and its Relevance for Network Epistemology

History and Philosophy of the Life Sciences (forthcoming)
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The history of the research on peptic ulcer disease is characterized by a premature abandonment of the bacterial hypothesis, which subsequently had its comeback, leading to the discovery of Helicobacter pylori – the major cause of the disease. In this paper we examine the received view on this case, according to which the primary reason for the abandonment of the bacterial hypothesis in the mid-twentieth century was a large-scale study by a prominent gastroenterologist Palmer, which suggested no bacteria could be found in the human stomach. To this end, we employ the methodof digital textual analysis and study the literature on the etiology of PUD published in the decade prior to Palmer’s article. Our findings suggest that the bacterial hypothesis had already been abandoned before the publication of Palmer’s paper, which challenges the widely held view that his study played a crucial role in the development of this episode. In view of this result, we argue that the PUD case does not illustrate harmful effects of a high degree of information flow, as it has frequently been claimed in the literature on network epistemology. Moreover, we argue that alternative examples of harmful effects of a high degree of information flow may be hard to find in the history of science.



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Dunja Šešelja
Eindhoven University of Technology
Bartosz Michal Radomski
Ruhr-Universität Bochum

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References found in this work

The Fate of Knowledge.Helen E. Longino - 2001 - Princeton University Press.
Is Water H2O? Evidence, Realism and Pluralism.Hasok Chang - 2012 - Boston Studies in the Philosophy and History of Science.
Illegitimate Values, Confirmation Bias, and Mandevillian Cognition in Science.Uwe Peters - 2021 - British Journal for the Philosophy of Science 72 (4):1061-1081.

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