Evolving scientific epistemologies and the artifacts of empirical philosophy of science: A reply concerning mesosomes [Book Review]

Biology and Philosophy 16 (5):627-652 (2001)
In a 1993 paper, I argued that empirical treatments of the epistemologyused by scientists in experimental work are too abstract in practice tocounter relativist efforts to explain the outcome of scientificcontroversies by reference to sociological forces. This was because, atthe rarefied level at which the methodology of scientists is treated byphilosophers, multiple mutually inconsistent instantiations of theprinciples described by philosophers are employed by contestingscientists. These multiple construals change within a scientificcommunity over short time frames, and these different versions ofscientific methodology can determine the outcome of a controversy. Iillustrated with a comparatively detailed analysis of the methodologyused by biologists debating the existence of an entity called thebacterial mesosome between the mid-1950s and the mid-1970s. This 1993piece has drawn several critiques in the philosophical literature. Inthis present piece I respond to these critiques and argue that they failto address the core argument of the original paper, and I reflectfurther on the methodologies of philosophers of science pursuingempirical or `naturalistic' epistemology.
Keywords electron microscopy  experiment  mesosomes  naturalized epistemology  relativism  robustness
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DOI 10.1023/A:1012038815107
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Jutta Schickore & Klodian Coko (2014). Using Multiple Means of Determination. International Studies in the Philosophy of Science 27 (3):295-313.
Hubertus Nederbragt (2003). Strategies to Improve the Reliability of a Theory: The Experiment of Bacterial Invasion Into Cultured Epithelial Cells. Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 34 (4):593-614.

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