Applied Ontology 10 (2):79-105 (2015)

Robert J. Rovetto
American Military University
The goal of this paper is two-fold: first, to emphasize causality in disease ontology and knowledge representation, presenting a general and cursory discussion of causality and causal chains; and second, to clarify and develop the River Flow Model of Diseases (RFM). The RFM is an ontological account of disease, representing the causal structure of pathology. It applies general knowledge of causality using the concept of causal chains. The river analogy of disease is explained, formal descriptions are offered, and the RFM disease definition is refined by describing causal chains in terms of causal relations. The definition is updated to coincide with the actual RFM classes found in its upper-level ontology, YAMATO, which brings to light some challenges in developing both YAMATO and the RFM. The RFM is also discussed in relation to another ontological account of disease. Strategies are offered toward interoperability between these theories.
Keywords ontology  applied ontology  philosophy of biology  biomedical ontology  metaphysics  causality  causation  knowledge representation  informatics  formal ontology
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DOI 10.3233/ao-150147
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References found in this work BETA

Causation as Simultaneous and Continuous.Michael Huemer & Ben Kovitz - 2003 - Philosophical Quarterly 53 (213):556–565.
Causation, Nomic Subsumption, and the Concept of Event.Jaegwon Kim - 1973 - Journal of Philosophy 70 (8):217-236.
The Facts of Causation.Max Urchs - 1997 - Erkenntnis 46 (2):277-279.

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