A fast method to estimate kinetic constants for enzyme inhibitors

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Acta Biotheoretica 49 (2):109-113 (2001)
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Abstract

We present a method to determine the reaction type and kinetic constants for enzyme inhibitors that decreases the number of experimental assays by at least a factor of five. It is based on a new theoretical formalism in terms of concentrations that dismisses the requirement of estimating initial velocities. Expressions for the time evolution of the concentrations of all the reactants are also given.

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2004

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10.1023/a:1010219527831

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