Asian Bioethics Review 11 (3):275-288 (2019)

G. Owen Schaefer
National University of Singapore
As opposed to a ‘one size fits all’ approach, precision medicine uses relevant biological, medical, behavioural and environmental information about a person to further personalize their healthcare. This could mean better prediction of someone’s disease risk and more effective diagnosis and treatment if they have a condition. Big data allows for far more precision and tailoring than was ever before possible by linking together diverse datasets to reveal hitherto-unknown correlations and causal pathways. But it also raises ethical issues relating to the balancing of interests, viability of anonymization, familial and group implications, as well as genetic discrimination. This article analyses these issues in light of the values of public benefit, justice, harm minimization, transparency, engagement and reflexivity and applies the deliberative balancing approach found in the Ethical Framework for Big Data in Health and Research to a case study on clinical genomic data sharing. Please refer to that article for an explanation of how this framework is to be used, including a full explanation of the key values involved and the balancing approach used in the case study at the end. Our discussion is meant to be of use to those involved in the practice as well as governance and oversight of precision medicine to address ethical concerns that arise in a coherent and systematic manner.
Keywords No keywords specified (fix it)
Categories (categorize this paper)
DOI 10.1007/s41649-019-00094-2
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy

 PhilArchive page | Other versions
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

Can Broad Consent Be Informed Consent?M. Sheehan - 2011 - Public Health Ethics 4 (3):226-235.
Broadening Consent--And Diluting Ethics?B. Hofmann - 2009 - Journal of Medical Ethics 35 (2):125-129.

View all 7 references / Add more references

Citations of this work BETA

Add more citations

Similar books and articles

The Precision Medicine Nation.Maya Sabatello & Paul S. Appelbaum - 2017 - Hastings Center Report 47 (4):19-29.
The Imaginary of Precision Public Health.Martha Kenney & Laura Mamo - 2020 - Medical Humanities 46 (3):192-203.
Precision Medicine Research: An Exception or An Exemplar?Emily A. Largent - 2019 - Journal of Law, Medicine and Ethics 47 (1):149-151.
Towards Precision Medicine; a New Biomedical Cosmology.M. W. Vegter - 2018 - Medicine, Health Care and Philosophy 21 (4):443-456.
Some Lingering Concerns About the Precision Medicine Initiative.Mark A. Rothstein - 2016 - Journal of Law, Medicine and Ethics 44 (3):520-525.
Structural Challenges of Precision Medicine.Mark A. Rothstein - 2017 - Journal of Law, Medicine and Ethics 45 (2):274-279.
The Potential of Medicine as a Resource for Philosophy.K. W. M. Fulford - 1991 - Theoretical Medicine and Bioethics 12 (1).


Added to PP index

Total views
120 ( #92,201 of 2,462,436 )

Recent downloads (6 months)
12 ( #60,443 of 2,462,436 )

How can I increase my downloads?


My notes