Consciousness and Cognition 20 (4):1050-1054 (2011)
Authors |
|
Abstract |
Previous work employing graph theory and nonlinear analysis has found increased spatial and temporal disorder, respectively, of functional brain connectivity in schizophrenia. We present a new method combining graph theory and nonlinear techniques that measures the temporal disorder of functional brain connections. Multichannel electroencephalographic data were windowed and functional networks were reconstructed using the minimum spanning trees of correlation matrices. Using a method based on Shannon entropy, we found elevated connection entropy in gamma activity of patients with schizophrenia; however, gamma connection entropy remained elevated in patients with schizophrenia even after a reduction in symptoms due to treatment with antipsychotics. Our results are consistent with several possibilities: aberrant functional connectivity is epiphenomenal to schizophrenia, aberrant functional connectivity is a central feature but antipsychotics reduce symptoms by an independent mechanism, or connection entropy is not an appropriately sensitive measure of brain abnormalities in schizophrenia
|
Keywords | No keywords specified (fix it) |
Categories | (categorize this paper) |
DOI | 10.1016/j.concog.2010.05.009 |
Options |
![]() ![]() ![]() ![]() |
Download options
References found in this work BETA
No references found.
Citations of this work BETA
Time Engineering in the Schizophrenias.Paul Brown - 2011 - Consciousness and Cognition 20 (4):1055-1058.
Similar books and articles
The Directionality and Functional Organization of Frontoparietal Connectivity During Consciousness and Anesthesia in Humans.UnCheol Lee, Seunghwan Kim, Gyu-Jeong Noh, Byung-Moon Choi, Eunjin Hwang & George A. Mashour - 2009 - Consciousness and Cognition 18 (4):1069-1078.
Schizophrenia is a Disease of General Connectivity More Than a Specifically “Social Brain” Network.Conrado Bosman, Enzo Brunetti & Francisco Aboitiz - 2004 - Behavioral and Brain Sciences 27 (6):856-856.
Cortex Functional Connectivity as a Neurophysiological Correlate of Hypnosis: An EEG Case Study.Andrew A. Fingelkurts, Alexander A. Fingelkurts, Sakari Kallio & Antti Revonsuo - 2007 - Neuropsychologia 45 (7):14521462.
Principles of Brain Connectivity Organization.Claus C. Hilgetag - 2006 - Behavioral and Brain Sciences 29 (1):18-19.
Probing Cortico-Cortical Interactions That Underlie the Multiple Sensory, Cognitive, and Everyday Functional Deficits in Schizophrenia.Gregory A. Light - 2004 - Behavioral and Brain Sciences 27 (6):799-799.
The Key Role of Prefrontal Cortex Structure and Function.Antonino Raffone & Gary L. Brase - 2006 - Behavioral and Brain Sciences 29 (1):22-22.
Persistent Operational Synchrony Within Brain Default-Mode Network and Self-Processing Operations in Healthy Subjects.Andrew A. Fingelkurts & Alexander A. Fingelkurts - 2011 - Brain and Cognition 75 (2):79-90.
Auditory Hallucinations, Network Connectivity, and Schizophrenia.Ralph E. Hoffman, Maxine Varanko, Thomas H. McGlashan & Michelle Hampson - 2004 - Behavioral and Brain Sciences 27 (6):860-861.
Functional Connectivity in the Brain and Human Intelligence.Vincent J. Schmithorst - 2007 - Behavioral and Brain Sciences 30 (2):169-170.
Backward Masking in Schizophrenia: Neuropsychological, Electrophysiological, and Functional Neuroimaging Findings.Jonathan K. Wynn & Michael F. Green - 2006 - In Gmen, Haluk; Breitmeyer, Bruno G. (2006). The First Half Second: The Microgenesis and Temporal Dynamics of Unconscious and Conscious Visual Processes. (Pp. 171-184). Cambridge, Ma, Us: Mit Press. Xi, 410 Pp.
Lifting the Screen on Neural Organization: Is Computational Functional Modeling Necessary?Damian Keil & Keith Davids - 2000 - Behavioral and Brain Sciences 23 (4):544-545.
Functional Connectivity of the Medial Temporal Lobe Relates to Learning and Awareness.Anthony Randal McIntosh, M. Natasha Rajah & Nancy J. Lobaugh - 2003 - Journal of Neuroscience 23 (16):6520-6528.
The Role of Psychology in Functional Localization Research.Barbara V. E. Klein - 1978 - PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1978:119 - 133.
NMDA-Receptor Hypofunction Versus Excessive Synaptic Elimination as Models of Schizophrenia.Ralph E. Hoffman & Thomas H. McGlashan - 2003 - Behavioral and Brain Sciences 26 (1):92-92.
An Evolutionary Theory of Schizophrenia: Cortical Connectivity, Metarepresentation, and the Social Brain.Jonathan Kenneth Burns - 2004 - Behavioral and Brain Sciences 27 (6):831-855.
Analytics
Added to PP index
2010-09-13
Total views
43 ( #261,271 of 2,499,305 )
Recent downloads (6 months)
1 ( #418,195 of 2,499,305 )
2010-09-13
Total views
43 ( #261,271 of 2,499,305 )
Recent downloads (6 months)
1 ( #418,195 of 2,499,305 )
How can I increase my downloads?
Downloads