Consciousness and Cognition 20 (4):1050-1054 (2011)

George Mashour
University of Michigan, Ann Arbor
Previous work employing graph theory and nonlinear analysis has found increased spatial and temporal disorder, respectively, of functional brain connectivity in schizophrenia. We present a new method combining graph theory and nonlinear techniques that measures the temporal disorder of functional brain connections. Multichannel electroencephalographic data were windowed and functional networks were reconstructed using the minimum spanning trees of correlation matrices. Using a method based on Shannon entropy, we found elevated connection entropy in gamma activity of patients with schizophrenia; however, gamma connection entropy remained elevated in patients with schizophrenia even after a reduction in symptoms due to treatment with antipsychotics. Our results are consistent with several possibilities: aberrant functional connectivity is epiphenomenal to schizophrenia, aberrant functional connectivity is a central feature but antipsychotics reduce symptoms by an independent mechanism, or connection entropy is not an appropriately sensitive measure of brain abnormalities in schizophrenia
Keywords No keywords specified (fix it)
Categories (categorize this paper)
DOI 10.1016/j.concog.2010.05.009
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

PhilArchive copy

Upload a copy of this paper     Check publisher's policy     Papers currently archived: 69,160
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

No references found.

Add more references

Citations of this work BETA

Time Engineering in the Schizophrenias.Paul Brown - 2011 - Consciousness and Cognition 20 (4):1055-1058.

Add more citations

Similar books and articles

Principles of Brain Connectivity Organization.Claus C. Hilgetag - 2006 - Behavioral and Brain Sciences 29 (1):18-19.
Functional Connectivity in the Brain and Human Intelligence.Vincent J. Schmithorst - 2007 - Behavioral and Brain Sciences 30 (2):169-170.
The Role of Psychology in Functional Localization Research.Barbara V. E. Klein - 1978 - PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1978:119 - 133.


Added to PP index

Total views
43 ( #261,271 of 2,499,305 )

Recent downloads (6 months)
1 ( #418,195 of 2,499,305 )

How can I increase my downloads?


My notes