Why continuing uncertainties are no reason to postpone challenge trials for coronavirus vaccines

Journal of Medical Ethics 46 (12):808-812 (2020)

Abstract

To counter the pandemic caused by severe acute respiratory syndrome coronavirus 2, some have proposed accelerating SARS-CoV-2 vaccine development through controlled human infection trials. These trials would involve the deliberate exposure of relatively few young, healthy volunteers to SARS-CoV-2. We defend this proposal against the charge that there is still too much uncertainty surrounding the risks of COVID-19 to responsibly run such a trial.

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Author Profiles

Nir Eyal
Harvard University
Lara Buchak
Princeton University

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