Philosophy of Science 85 (00):1090-1101 (2018)

Authors
Jacqueline Anne Sullivan
University of Western Ontario
Abstract
Optogenetic techniques are described as “revolutionary” for the unprecedented causal control they allow neuroscientists to exert over neural activity in awake behaving animals. In this paper, I demonstrate by means of a case study that optogenetic techniques will only illuminate causal links between the brain and behavior to the extent that their error characteristics are known and, further, that determining these error characteristics requires comparison of optogenetic techniques with techniques having well known error characteristics and consideration of the broader neural and behavioral context in which the targets of optogenetic interventions are situated.
Keywords optogenetics  pluralism  experimentation  neuroscience  error
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Reprint years 2018
DOI 10.1086/699724
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Is Water H2O? Evidence, Realism and Pluralism.Hasok Chang - 2012 - Boston Studies in the Philosophy and History of Science.
Making Things Happen. A Theory of Causal Explanation.Michael Strevens - 2007 - Philosophy and Phenomenological Research 74 (1):233-249.
Scientific Perspectivism.Ronald N. Giere - 2006 - University of Chicago Press.

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