Microbes and Infection 13:983-991 (2011)
The immune system, to protect the body, must discriminate between the pathogenic and non-pathogenic microbes and respond to them in different ways. How the mucosal immune system manages to make this distinction is poorly understood. We suggest here that the distinction between pathogenic and non-pathogenic microbes is made by an integrated system rather than by single types of cells or single types of receptors; a systems biology approach is needed to understand immune recognition.
|Keywords||Immune recognition Systems immunology Pathogen Pathogen-associated molecular motif|
|Categories||categorize this paper)|
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Immune Balance: The Development of the Idea and its Applications.Bartlomiej Swiatczak - 2014 - Journal of the History of Biology 47:411-442.
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