Curing cancer? Patrick Lee's path to the reovirus treatment


Authors
Paul Thagard
University of Waterloo
Abstract
This article provides a historical, philosophical, and psychological analysis of the recent discovery that reoviruses are oncolytic, capable of infecting and destroying many kinds of cancer cells. After describing Patrick Lee's very indirect path to this discovery, I discuss the implications of this case for understanding the nature of scientific discovery, including the economy of research, anomaly recognition, hypothesis formation, and the role of emotion in scientific thinking. Lee's discoveries involved a combination of serendipity, abductive and deductive inference, and emotional cognition.
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DOI 10.1080/02698590120118846
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References found in this work BETA

Coherence in Thought and Action (M. Amini).P. Thagard - 2000 - Philosophical Books 43 (2):136-140.
How Scientists Explain Disease.Paul Thagard - 1999 - Princeton University Press.
Beauty & Revolution in Science.James W. McAllister - 1996 - Cornell University Press.
Collected Papers.Charles S. Peirce - 1931 - Cambridge: Belknap Press of Harvard University Press.

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Citations of this work BETA

Pathways to Biomedical Discovery.Paul Thagard - 2003 - Philosophy of Science 70 (2):235-254.
How to Be a Successful Scientist.Paul Thagard - 2005 - In M. Gorman, R. Tweney, D. Gooding & A. Kincannon (eds.), Scientific and Technological Thinking. Erlbaum. pp. 159--171.

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