Curing cancer? Patrick Lee's path to the reovirus treatment

Paul Thagard
University of Waterloo
This article provides a historical, philosophical, and psychological analysis of the recent discovery that reoviruses are oncolytic, capable of infecting and destroying many kinds of cancer cells. After describing Patrick Lee's very indirect path to this discovery, I discuss the implications of this case for understanding the nature of scientific discovery, including the economy of research, anomaly recognition, hypothesis formation, and the role of emotion in scientific thinking. Lee's discoveries involved a combination of serendipity, abductive and deductive inference, and emotional cognition.
Keywords No keywords specified (fix it)
Categories (categorize this paper)
DOI 10.1080/02698590120118846
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

Our Archive

Upload a copy of this paper     Check publisher's policy     Papers currently archived: 48,857
External links

Setup an account with your affiliations in order to access resources via your University's proxy server
Configure custom proxy (use this if your affiliation does not provide a proxy)
Through your library

References found in this work BETA

Coherence in Thought and Action (M. Amini).P. Thagard - 2000 - Philosophical Books 43 (2):136-140.
How Scientists Explain Disease.Paul Thagard - 1999 - Princeton University Press.
Beauty & Revolution in Science.James W. McAllister - 1996 - Cornell University Press.
Collected Papers.Charles S. Peirce - 1931 - Cambridge: Belknap Press of Harvard University Press.

View all 10 references / Add more references

Citations of this work BETA

Pathways to Biomedical Discovery.Paul Thagard - 2003 - Philosophy of Science 70 (2):235-254.
How to Be a Successful Scientist.Paul Thagard - 2005 - In M. Gorman, R. Tweney, D. Gooding & A. Kincannon (eds.), Scientific and Technological Thinking. Erlbaum. pp. 159--171.

View all 6 citations / Add more citations

Similar books and articles


Added to PP index

Total views
39 ( #238,241 of 2,309,545 )

Recent downloads (6 months)
5 ( #204,784 of 2,309,545 )

How can I increase my downloads?


My notes

Sign in to use this feature