Bayesian Inference and its Application to Meta-Analysis of Epidemiologic Data

Dissertation, The University of Texas Health Sciences Center at Houston School of Public Health (1991)

In Part One, the foundations of Bayesian inference are reviewed, and the technicalities of the Bayesian method are illustrated. Part Two applies the Bayesian meta-analysis program, the Confidence Profile Method , to clinical trial data and evaluates the merits of using Bayesian meta-analysis for overviews of clinical trials. ;The Bayesian method of meta-analysis produced similar results to the classical results because of the large sample size, along with the input of a non-preferential prior probability distribution. These results were anticipated through explanations in Part One of the mechanics of the Bayesian approach
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