The importance of modeling comorbidity using an intra-individual, time-series approach

Behavioral and Brain Sciences 33 (2-3):172-173 (2010)
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Abstract

We suggest that the network approach to comorbidity (Cramer et al.) is best examined by using longitudinal, multi-measurement, intra-individual data. Employment of time-series analysis to the examination of the generalized anxiety disorder and major depressive disorder comorbidity enables a detailed appreciation of fluctuations and causal trajectories in terms of both symptoms and cognitive vulnerability

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