Since the arrival of Translational Medicine, as both a term and movement in the late 1990s, it has been associated almost exclusively with attempts to accelerate the “translation” of research-laboratory findings to improve efficacy and outcomes in clinical practice. This framing privileges one source of change in medicine, that from bench-to-bedside. In this article we dig into the history of translation research to identify and discuss three other types of translational work in medicine that can also reshape ideas, practices, institutions, behaviours, or all of these, to produce transformations in clinical effectiveness. These are: making accessible state-of-the-art knowledge and best practice across the medical profession; remodelling and creating institutions to better develop and make available specialist knowledge and practice; and improving public and patient understandings of disease prevention, symptoms and treatments. We do so by examining the work of William S. C. Copeman, a dominant figure in British rheumatology from the 1930 through the late 1960s. Throughout his long career, Copeman blended approaches to “translation” in order to produce transformative change in clinical medicine, making his work an exemplar of our expanded notion of TM.
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DOI 10.1007/s40656-020-00330-1
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Phenylbutazone : one drug across two species.Michael Worboys & Elizabeth Toon - 2018 - History and Philosophy of the Life Sciences 40 (2):27.
Cortisone Therapy: A Challenge to Academic Medicine in 1949-1952.G. Hetenyi & J. Karsh - 1996 - Perspectives in Biology and Medicine 40 (3):426-439.

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