Bioethics 29 (9):631-638 (2015)

Authors
Anthony Wrigley
Keele University
John Appleby
King's College London
Abstract
Mitochondrial replacement techniques have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer and Maternal Spindle Transfer. It examines how questions of identity impact on the ethical evaluation of each technique and argues that there is an important difference between the two. PNT, it is argued, is a form of therapy based on embryo modification while MST is, instead, an instance of selective reproduction. The article's main ethical conclusion is that, in some circumstances, there is a stronger obligation to use PNT than MST
Keywords reproductive technology  identity  ethics  mitochondrial replacement  genetics
Categories (categorize this paper)
DOI 10.1111/bioe.12187
Options
Edit this record
Mark as duplicate
Export citation
Find it on Scholar
Request removal from index
Revision history

Download options

Our Archive


Upload a copy of this paper     Check publisher's policy     Papers currently archived: 50,447
Through your library

References found in this work BETA

Naming and Necessity.Saul Kripke - 1981 - Philosophy 56 (217):431-433.
Naming and Necessity.S. Kripke - 1972 - Tijdschrift Voor Filosofie 45 (4):665-666.
On The Plurality of Worlds.Graeme Forbes - 1988 - Philosophical Quarterly 38 (151):222-240.

View all 7 references / Add more references

Citations of this work BETA

Can Reproductive Genetic Manipulation Save Lives?G. Owen Schaefer - 2020 - Medicine, Health Care and Philosophy.
What Is the Value of Three-Parent IVF?Tina Rulli - 2016 - Hastings Center Report 46 (4):38-47.
Should Mitochondrial Donation Be Anonymous?John B. Appleby - 2018 - Journal of Medicine and Philosophy 43 (2):261-280.

View all 15 citations / Add more citations

Similar books and articles

Gene Replacement Therapy in the CNS: A View From the Retina.Gail M. Seigel - 1995 - Behavioral and Brain Sciences 18 (1):69-69.
Identity, Harm, and the Ethics of Reproductive Technology.Janet Malek - 2006 - Journal of Medicine and Philosophy 31 (1):83 – 95.
Choosing Future People: Reproductive Technologies and Identity.Mark Greene - 2009 - In Vardit Ravitsky, Autumn Fiester & Arthur L. Caplan (eds.), The Penn Center Guide to Bioethics. Springer Publishing Company. pp. 307-317.
Germ-Line Therapy for Mitochondrial Disease: Some Ethical Objections.Helen Watt - 1999 - Cambridge Quarterly of Healthcare Ethics 8 (1):88.
Respect for Persons, Identity, and Information Technology.Robin S. Dillon - 2010 - Ethics and Information Technology 12 (1):17-28.

Analytics

Added to PP index
2015-10-20

Total views
27 ( #359,782 of 2,326,399 )

Recent downloads (6 months)
4 ( #210,918 of 2,326,399 )

How can I increase my downloads?

Downloads

My notes