Some Ethical Concerns About Human Induced Pluripotent Stem Cells

Science and Engineering Ethics 22 (5):1277-1284 (2016)

Abstract
Human induced pluripotent stem cells can be obtained from somatic cells, and their derivation does not require destruction of embryos, thus avoiding ethical problems arising from the destruction of human embryos. This type of stem cell may provide an important tool for stem cell therapy, but it also results in some ethical concerns. It is likely that abnormal reprogramming occurs in the induction of human induced pluripotent stem cells, and that the stem cells generate tumors in the process of stem cell therapy. Human induced pluripotent stem cells should not be used to clone human beings, to produce human germ cells, nor to make human embryos. Informed consent should be obtained from patients in stem cell therapy.
Keywords Ethical concerns  Human induced pluripotent stem cells  Reprogramming  Tumorigenicity  Human cloning  Human germ cell  Human embryo  Informed consent
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DOI 10.1007/s11948-015-9693-6
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