Should post-trial provision of beneficial experimental interventions be mandatory in developing countries?

Journal of Medical Ethics 34 (3):188-192 (2008)
  Copy   BIBTEX


The need for continuing provision of beneficial experimental interventions after research is concluded remains a controversial topic in bioethics for research. Based on the principle of beneficence, justice as reciprocity, concerns about exploitation and fair benefits, participants should be able to have continuing access to benefits beyond the research period. However, there is no consensus about whether or not post-trial provision of beneficial interventions should be mandatory for participants from developing countries. This paper summarises recommendations from international and national guidelines. Ethical principles and practical issues relating to post-trial provision are also discussed. In conclusion, post-trial provision is not necessary in all situations and a set of criteria are proposed to identify the situations that beneficial interventions should be provided beyond the research period. However, mandatory post-trial supply of beneficial experimental interventions should be assured for those who still need and are able to benefit from them but have no alternative access. Mandatory provision is based on universal bioethical principles such as beneficence and justice. Furthermore, difficulties associated with implementation of post-trial provision are not unmanageable. Careful advanced planning and a comprehensive partnership among relevant parties would be very helpful in solving these difficulties in practice, which therefore should not be taken as an excuse to escape post-trial responsibility



    Upload a copy of this work     Papers currently archived: 94,678

External links

Setup an account with your affiliations in order to access resources via your University's proxy server

Through your library

Similar books and articles

Post-trial access to treatment: corporate best practices.Irene Schipper & Silvia Colona - 2015 - SOMO Centre for Research on Multinational Corporations.


Added to PP

28 (#570,287)

6 months
10 (#396,711)

Historical graph of downloads
How can I increase my downloads?