Article published in Progress in Human Geography, Aug 2017. This is a pre-publication version of the article ; please see early online version at publisher website for final version.: This article examines rhythmanalysis within the context of Henri Lefebvre's critique of everyday life and identifies gaps in his framework from the vantage point of intersectional feminist scholarship. Intersectional rhythmanalysis, I argue, provides a framework - Géographie – Nouvel article.

This book provides an introduction to Plato’s work that gives a clear statement of what Plato has to say about the problems of thought and life. In particular, it tells the reader just what Plato says, and makes no attempt to force a system on the Platonic text or to trim Plato’s works to suit contemporary philosophical tastes. The author also gives an account that has historical fidelity - we cannot really understand the Republic or the Gorgias if we forget (...) that the Athens of the conversations is meant to be the Athens of Nicias or Cleon, not the very different Athens of Plato’s own manhood. To understand Plato’s thought we must see it in the right historical perspective. (shrink)

This book provides an introduction to Plato’s work that gives a clear statement of what Plato has to say about the problems of thought and life. In particular, it tells the reader just what Plato says, and makes no attempt to force a system on the Platonic text or to trim Plato’s works to suit contemporary philosophical tastes. The author also gives an account that has historical fidelity - we cannot really understand the Republic or the Gorgias if we forget (...) that the Athens of the conversations is meant to be the Athens of Nicias or Cleon, not the very different Athens of Plato’s own manhood. To understand Plato’s thought we must see it in the right historical perspective. (shrink)

Objectives To evaluate whether the requirement of “minimal risk and burden” for paediatric research without direct benefit to the subjects compromises the ability to obtain data necessary for improving paediatric care. To provide evidence-based reflections on the EU recommendation that allows for a higher level of risk. Design and setting Systematic analysis of the approval/rejection decisions made by the Dutch Central Committee on Research involving Human Subjects (CCMO). Review methods The analysis included 165 proposals for paediatric research without direct benefit (...) that were reviewed by the CCMO between January, 2000, and July, 2007. A separate, in-depth analysis of all drug studies included 18 early phase drug studies and nine other drug studies without direct benefit. Results 11 out of 165 studies were definitively rejected because the CCMO did not regard the risk and/or burden to be minimal. In three of these 11 cases (including two early phase drug studies) the requirement of minimal risk and burden was cited as the only reason for rejection. Four other early phase drug studies also involved risks and/or burdens that were not regarded to be minimal but were nevertheless approved. Conclusions The requirement of minimal risk and burden, aiming to protect research subjects, occasionally leads to rejection of protocols. Early phase drug studies relatively often do not comply with the requirement. Committees may find ways to approve important studies that formally should be rejected, but that is not a desirable solution. The regulatory framework should be revised to make such occasional exceptions to the requirement legitimate and transparent. (shrink)

Research involving children or other incompetent subjects who are deemed unable to provide informed consent is complex, particularly in the case of research that does not directly benefit the research subjects themselves. The Helsinki Declaration, the World Medical Association's landmark document for research ethics, therefore states that incompetent research subjects must not be included in such research unless it entails only minimal risk and minimal burden. In this paper, we argue that now that research in these groups is expected to (...) expand, this undifferentiated minimal risk and burden requirement does not suffice any more. In the upcoming revision of the Declaration, the paragraph at stake should be refined in such a way that it is not unnecessarily restrictive or more permissive than can be ethically justified. Our first recommendation is to stimulate research ethics committees to identify more accurately those risks and burdens that the research subjects must undergo solely for research purposes by distinguishing between two types of study procedures instead of between two types of studies. Our second recommendation is to allow for exceptions to the minimal risk and burden requirement in cases of exceptionally valuable studies that involve subjects who can give their assent to participate in the study and that involve at most a minor increase over minimal risk and/or burden. (shrink)

OBJECTIVES: To report the outcome of applications to 43 research ethics committees. SETTING: Four regional health authorities in England. FINDINGS: The research ethics committees varied considerably in their practices. The time lapse until notification of the outcome of the approval ranged from just under one week to 23 weeks with a mean of 8.6 weeks. Four research ethics committees failed to notify the research team of an outcome of their request for approval. CONCLUSION: A national research ethics committee is needed (...) to review national and multi-location research studies in the light of the fragmented and variable practice of local research ethics committees. (shrink)

In this paper, I will reread the history of molecular genetics from a psychoanalytical angle, analysing it as a case history. Building on the developmental theories of Freud and his followers, I will distinguish four stages, namely: (1) oedipal childhood, notably the epoch of model building (1943–1953); (2) the latency period, with a focus on the development of basic skills (1953–1989); (3) adolescence, exemplified by the Human Genome Project, with its fierce conflicts, great expectations and grandiose claims (1989–2003) and (4) (...) adulthood (2003–present) during which revolutionary research areas such as molecular biology and genomics have achieved a certain level of normalcy—have evolved into a normal science. I will indicate how a psychoanalytical assessment conducted in this manner may help us to interpret and address some of the key normative issues that have been raised with regard to molecular genetics over the years, such as ‘relevance’, ‘responsible innovation’ and ‘promise management’. (shrink)

In classical writing the description of personal appearance was attempted in various ways. At one extreme the mere ‘passport-identification’ was concernedto enumerate distinguishing characteristics in order to ensure, for example, that a runaway slave or a recalcitrant taxpayer could be identified.

It is a point of some interest to the historian of the social and intellectual development of Athens to determine, if possible, the exact dates between which the philosopher Anaxagoras made that city his home. As everyone knows, the tradition of the third and later centuries was not uniform. The dates from which the Alexandrian chronologists had to arrive at their results may be conveniently summed up under three headings, date of Anaxagoras' arrival at Athens, date of his prosecution and (...) escape to Lampsacus, length of his residence at Athens, The received account , was that Anaxagoras was twenty years old at the date of the invasion of Xerxes and lived to be seventy-two. This was apparently why Apollodorus placed his birth in Olympiad 70 and his death in Ol. 88. I, thus giving the years 500–428 B.C. of our reckoning, The further statement of Apollodorus that Anaxagoras xs1F24ρξατο xs03D5ιλοσοxs03D5εxs1FD6ν xs22EFπxs22EF Καλλίον has given rise to discussion; but when we remember that Demetrius of Phalerum had made what ‘Diogenes’ regards as an equivalent statement in his register of archons, and had said that Anaxagoras was twenty years old at the time, I think there can be no doubt of the meaning. Demetrius had clearly mentioned something about Anaxagoras which was looked on as giving the date at which he ‘began to philosophize,’ and had given his age at the time. The natural interpretation is that Demetrius mentioned the year of Anaxagoras’ arrival at Athens, and that this was taken as the time at which he ρξαtο φιλοσοφεlσ And it is further reasonable to suppose that this date was the source of the further statement of Demetrius, that Anaxagoras was born in or about 500 B.C. We may, I think, infer that Demetrius recorded the arrival of Anaxagoras in Athens under the year 480, giving his approximate age at that time. (shrink)

Modern scholars have been concerned with the hostility shown to Alexander by the Hellenistic schools of philosophy. Two literary portraits have been distinguished, the Peripatetic and the Stoic, the former deriving from Theophrastus' book on Callisthenes, or starting with this work the Peripatetics worked out a theory of and applied it to Alexander, in order to belittle his achievements. It was a case of giving sophisticated expression to the kind of crude resentment expressed by Demades.

More than simply a listing and abstract discussion of ideas, the book presents a searching analysis of Aristotle's thought, both in terms of its historical ...