Results for 'Adrian M. Thorogood'

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  1.  36
    Introduction: Sharing Data in a Medical Information Commons.Amy L. McGuire, Mary A. Majumder, Angela G. Villanueva, Jessica Bardill, Juli M. Bollinger, Eric Boerwinkle, Tania Bubela, Patricia A. Deverka, Barbara J. Evans, Nanibaa' A. Garrison, David Glazer, Melissa M. Goldstein, Henry T. Greely, Scott D. Kahn, Bartha M. Knoppers, Barbara A. Koenig, J. Mark Lambright, John E. Mattison, Christopher O'Donnell, Arti K. Rai, Laura L. Rodriguez, Tania Simoncelli, Sharon F. Terry, Adrian M. Thorogood, Michael S. Watson, John T. Wilbanks & Robert Cook-Deegan - 2019 - Journal of Law, Medicine and Ethics 47 (1):12-20.
    Drawing on a landscape analysis of existing data-sharing initiatives, in-depth interviews with expert stakeholders, and public deliberations with community advisory panels across the U.S., we describe features of the evolving medical information commons. We identify participant-centricity and trustworthiness as the most important features of an MIC and discuss the implications for those seeking to create a sustainable, useful, and widely available collection of linked resources for research and other purposes.
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  2. Rationality and the Structure of the Self Volume II: A Kantian Conception.Adrian M. S. Piper - 2013 - APRA Foundation.
    Adrian Piper argues that the Humean conception can be made to work only if it is placed in the context of a wider and genuinely universal conception of the self, whose origins are to be found in Kant’s Critique of Pure Reason. This conception comprises the basic canons of classical logic, which provide both a model of motivation and a model of rationality. These supply necessary conditions both for the coherence and integrity of the self and also for unified (...)
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  3. Detecting Awareness in the Conscious State.Adrian M. Owen, Martin R. Coleman, Melanie Boly, Matthew H. Davis, Steven Laureys, Dietsje Jolles & John D. Pickard - 2006 - Science 313:1402.
  4. Impartiality, Compassion, and Modal Imagination.Adrian M. S. Piper - 1991 - Ethics 101 (4):726-757.
    We need modal imagination in order to extend our conception of reality - and, in particular, of human beings - beyond our immediate experience in the indexical present; and we need to do this in order to preserve the significance of human interaction. To make this leap of imagination successfully is to achieve not only insight but also an impartial perspective on our own and others' inner states. This perspective is a necessary condition of experiencing compassion for others. This is (...)
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  5. Rationality and the Structure of the Self, Volume I: The Humean Conception.Adrian M. S. Piper - 2008 - APRA Foundation Berlin.
    The Humean conception of the self consists in the belief-desire model of motivation and the utility-maximizing model of rationality. This conception has dominated Western thought in philosophy and the social sciences ever since Hobbes’ initial formulation in Leviathan and Hume’s elaboration in the Treatise of Human Nature. Bentham, Freud, Ramsey, Skinner, Allais, von Neumann and Morgenstern and others have added further refinements that have brought it to a high degree of formal sophistication. Late twentieth century moral philosophers such as Rawls, (...)
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  6.  30
    An Implementation Framework for the Feedback of Individual Research Results and Incidental Findings in Research.Adrian Thorogood, Yann Joly, Bartha Maria Knoppers, Tommy Nilsson, Peter Metrakos, Anthoula Lazaris & Ayat Salman - 2014 - BMC Medical Ethics 15 (1):88.
    This article outlines procedures for the feedback of individual research data to participants. This feedback framework was developed in the context of a personalized medicine research project in Canada. Researchers in this domain have an ethical obligation to return individual research results and/or material incidental findings that are clinically significant, valid and actionable to participants. Communication of individual research data must proceed in an ethical and efficient manner. Feedback involves three procedural steps: assessing the health relevance of a finding, re-identifying (...)
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  7.  21
    Legal Frameworks for Addressing the Well-Being of Terminally Ill Children.Adrian M. Viens & Jeffrey R. Bibbee - 2005 - American Journal of Bioethics 5 (1):74-76.
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  8.  13
    Socio-Economic Status and Inducement to Participate.Adrian M. Viens - 2001 - American Journal of Bioethics 1 (2):1f-2f.
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  9. “Seeing Things”.Adrian M. S. Piper - 1991 - Southern Journal of Philosophy 29 (S1):29-60.
    In an earlier discussion, I argued that Kant's moral theory satisfies some of the basic criteria for being a genuine theory: it includes testable hypotheses, nomological higher-and lower-level laws, theoretical constructs, internal principles, and bridge principles. I tried to show that Kant's moral theory is an ideal, descriptive deductive-nomological theory that explains the behavior of a fully rational being and generates testable hypotheses about the moral behavior of actual agents whom we initially assume to conform to its theoretical constructs. I (...)
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  10.  64
    Response to Comments on "Detecting Awareness in the Vegetative State".Adrian M. Owen, Martin R. Coleman, Melanie Boly, Matthew H. Davis, Steven Laureys, Dietsje Jolles & John D. Pickard - 2007 - Science 315 (5816).
  11. Moral Theory and Moral Alienation.Adrian M. S. Piper - 1987 - Journal of Philosophy 84 (2):102-118.
    Most moral theories share certain features in common with other theories. They consist of a set of propositions that are universal, general, and hence impartial. The propositions that constitute a typical moral theory are (1) universal, in that they apply to all subjects designated as within their scope. They are (2) general, in that they include no proper names or definite descriptions. They are therefore (3) impartial, in that they accord no special privilege to any particular agent's situation which cannot (...)
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  12. Using Functional Magnetic Resonance Imaging to Detect Covert Awareness in the Vegetative State.Adrian M. Owen, Martin R. Coleman, Melanie Boly, Matthew H. Davis, Steven Laureys & John D. Pickard - 2007 - Archives of Neurology 64 (8):1098-1102.
  13. Utility, Publicity, and Manipulation.Adrian M. S. Piper - 1978 - Ethics 88 (3):189-206.
    In our dealings with young children, we often get them to do or think things by arranging their environments in certain ways; by dissembling, simplifying, or ambiguating the facts in answer to their queries; by carefully selecting the states of affairs, behavior of others, and utterances to which they shall be privy. We rightly justify these practices by pointing out a child's malleability, and the necessity of paying close attention to formative influences during its years of growth. This filtering of (...)
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  14. Kant's Self-Legislation Procedure Reconsidered.Adrian M. S. Piper - 2012 - Kant Studies Online 2012 (1):203-277.
    Most published discussions in contemporary metaethics include some textual exegesis of the relevant contemporary authors, but little or none of the historical authors who provide the underpinnings of their general approach. The latter is usually relegated to the historical, or dismissed as expository. Sometimes this can be a useful division of labor. But it can also lead to grave confusion about the views under discussion, and even about whose views are, in fact, under discussion. Elijah Millgram’s article, “Does the Categorical (...)
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  15.  27
    Using a Hierarchical Approach to Investigate Residual Auditory Cognition in Persistent Vegetative State.Adrian M. Owen, Martin R. Coleman, D. K. Menon, E. L. Berry, I. S. Johnsrude, J. M. Rodd, Matthew H. Davis & John D. Pickard - 2006 - In Steven Laureys (ed.), Boundaries of Consciousness. Elsevier.
  16. Higher-Order Discrimination.Adrian M. S. Piper - 1990 - In Amelie O. Rorty & Owen Flanagan (eds.), Identity, Character and Morality. Cambridge, Mass: MIT Press. pp. 285-309.
    This discussion treats a set of familiar social derelictions as consequences of the perversion of a universalistic moral theory in the service of an ill-considered or insufficiently examined personal agenda.The set includes racism, sexism, anti-Semitism, homophobia, and class elitism, among other similar pathologies, under the general heading of discrimination. The perversion of moral theory from which these derelictions arise, I argue, involves restricting its scope of application to some preferred subgroup of the moral community of human beings. -/- The following (...)
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  17.  12
    Alive Inside.Andrew Peterson, Adrian M. Owen & Jason Karlawish - 2020 - Bioethics 34 (3):295-305.
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  18. Xenophobia and Kantian Rationalism.Adrian M. S. Piper - 1993 - Philosophical Forum 24 (1-3):188-232.
    The purpose of this discussion is twofold. First, I want to shed some light on Kant's concept of personhood as rational agency, by situating it in the context of the first Critique's conception of the self as defined by its rational dispositions. I hope to suggest that this concept of personhood cannot be simply grafted onto an essentially Humean conception of the self that is inherently inimical to it, as I believe Rawls, Gewirth, and others have tried to do. Instead (...)
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  19.  20
    International Guidelines for Privacy in Genomic Biobanking.Adrian Thorogood & Ma'N. H. Zawati - 2015 - Journal of Law, Medicine and Ethics 43 (4):690-702.
    In an era of unrivalled sequencing, computation and networking capability, international sharing of genomic samples and data is becoming a modus operandi for modern medical research. Researchers are collaborating to establish large collections with global scale. Having never before set foot outside the cell, the molecules that shape us are being digitized and launched across the globe. Protecting individual privacy interests in this information is a central challenge of the genomic research era. This article reviews international privacy norms governing human (...)
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  20.  72
    Brain Function in Coma, Vegetative State, and Related Disorders.Steven Laureys, Adrian M. Owen & Nicholas D. Schiff - 2004 - Lancet Neurology 3:537-546.
  21.  20
    HERA Today, Gone Tomorrow?Adrian M. Owen - 2003 - Trends in Cognitive Sciences 7 (9):383-384.
  22. A Distinction Without a Difference.Adrian M. S. Piper - 1982 - Midwest Studies in Philosophy 7 (1):403-435.
    I wish to defend the claim that given the content and structure of any moral theory we are likely to find palatable, there is no way of uniquely breaking down that theory into either consequentialist or deontological elements. Indeed, once we examine the actual structure of any such theory more closely, we see that it can be classified in either way arbitrarily. Hence if we ignore the metaethical pronouncements often made by adherents of the consequentialist-deontological distinction, we are quickly led (...)
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  23. Intellektuelle Intuition in Kants erster Kritik und Samkhya-Philosophie.Adrian M. S. Piper - 2007 - In Elke Falat & Thomas Thiel (eds.), into it. Hildesheim, Germany: Kunstverein Hildesheim/Kehrerverlag Heidelberg. pp. 94-104.
  24. Kant's Two Solutions to the Free Rider Problem.Adrian M. S. Piper - 2012 - Kant Yearbook 4 (1).
    Kant identifies what are in fact Free Riders as the most noxious species of polemicists. Kant thinks polemic reduces the stature and authority of reason to a method of squabbling that destabilizes social equilibrium and portends disintegration into the Hobessian state of nature. In the first Critique, Kant proposes two textually related solutions to the Free Rider problem.
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  25.  13
    Functional Magnetic Resonance Imaging, Covert Awareness, and Brain Iniury.Adrian M. Owen - 2011 - In Judy Illes & Barbara J. Sahakian (eds.), Oxford Handbook of Neuroethics. Oxford University Press. pp. 135.
    Rapid technological advances have produced a variety of novel techniques that allow a comprehensive assessment of brain function to be combined with detailed information about brain structure and connectivity. Any assessment that is based on exhibited behavior after brain injury will be prone to error for a number of reasons. These questions are explored in the context of recent studies in both healthy populations and brain injured patients that have sought to investigate covert awareness through the use of functional neuroimaging. (...)
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  26.  5
    When Thoughts Become Actions : Neuroimaging in Non-Responsive Patients.Adrian M. Owen - 2012 - In Sarah Richmond, Geraint Rees & Sarah J. L. Edwards (eds.), I Know What You're Thinking: Brain Imaging and Mental Privacy. Oxford University Press. pp. 73.
  27. Property and the Limits of the Self.Adrian M. S. Piper - 1980 - Political Theory 8 (1):39-64.
    THE MAIN OBJECTIVES of the following discussions are, first, to show the logical inconsistency of Hegel’s theory of the necessity of private property and, second, to show its exegetical inconsistency with the most plausible and consistent interpretations of Hegel’s theory of the self and its relation to the state in Ethical Life. I begin with the latter objective, by distinguishing three basic conceptions of the self that can be gleaned from various passages in the Philosophy of Right. I suggest viable (...)
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  28. Instrumentalism, Objectivity, and Moral Justification.Adrian M. S. Piper - 1986 - American Philosophical Quarterly 23 (4):373 - 381.
    I want to examine critically a certain strategy of moral justification which I shall call instrumentalism. By this I mean the view that a moral theory is rationally justified if the actions, life-plan, or set of social arrangements it prescribes can be shown to be the best means to the achievement of an agent's final ends, whatever these may be. Instrumentalism presupposes a commitment to what I shall call the Humean conception of the self. By this I mean a certain (...)
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  29.  17
    Goods and Virtues.Adrian M. S. Piper - 1986 - Journal of Philosophy 83 (8):468-473.
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  30. Personal Continuity and Instrumental Rationality in Rawls’ Theory of Justice.Adrian M. S. Piper - 1987 - Social Theory and Practice 13 (1):49-76.
    I want to examine the implications of a metaphysical thesis which is presupposed in various objections to Rawls' theory of justice.Although their criticisms differ in many respects, they concur in employing what I shall refer to as the continuity thesis. This consists of the following claims conjointly: (1) The parties in the original position (henceforth the OP) are, and know themselves to be, fully mature persons who will be among the members of the well-ordered society (henceforth the WOS) which is (...)
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  31. Government Support for Unconventional Works of Art.Adrian M. S. Piper - 1992 - In Andrew Buchwalter (ed.), Culture and Democracy: Social and Ethical Issues in Public Support for the Arts and Humanities. Boulder: Westview Press. pp. 217-222.
    My aim in this discussion is to argue, not only that government should provide funding for the arts, but a fortiori that it should provide funding for unconventional, disruptive works of art.
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  32. Hume on Rational Final Ends.Adrian M. S. Piper - 1988 - Philosophy Research Archives 14:193-228.
    Historically, the view, prevalent in contemporary economics and decision theory as well as philosophy, that rational action consists simply in satisfying one’s desires, whatever they may be, as efficiently as possible, is to be found first in Book II of Hume’s Treatise of Human Nature. This view has counterintuitive and self-refuting implications, in that it recognizes as rational behavior that may reveal a clear degree of irresponsibility or psychological instability. Accordingly, many Hume scholars have tried to show recently that this (...)
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  33.  93
    The Emergence of Norms.Adrian M. S. Piper - 1988 - Philosophical Review 97 (1):99.
    Book review of "The Emergence of Norms.
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  34. Pseudorationality.Adrian M. S. Piper - 1988 - In Brian P. McLaughlin & Amelie O. Rorty (eds.), Perspectives on Self-Deception. University of California Press. pp. 173--197.
    I want to argue that self-deception is a species of a more general phenomenon, which I shall call pseudorationality, which in turn is necessitated by what I shall describe as our highest-order disposition to literal self-preservation. By "literal self-preservation," I mean preservation of the rational intelligibility of the self, in the face of recalcitrant facts that invariably threaten it.
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  35. Kant on the Objectivity of the Moral Law (1994).Adrian M. S. Piper - 1997 - In Andrews Reath, Barbara Herman & Christine Korsgaard (eds.), Reclaiming the History of Ethics: Essays for John Rawls. Cambridge University Press.
    In 1951 John Rawls expressed these convictions about the fundamental issues in metaethics: [T]he objectivity or the subjectivity of moral knowledge turns, not on the question whether ideal value entities exist or whether moral judgments are caused by emotions or whether there is a variety of moral codes the world over, but simply on the question: does there exist a reasonable method for validating and invalidating given or proposed moral rules and those decisions made on the basis of them? For (...)
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  36.  81
    The Enterprise of Socratic Metaethics.Adrian M. S. Piper - 2000 - In Naomi Zack (ed.), Women of Color and Philosophy, A Critical Reader. London: Blackwell. pp. 91-131.
    That human beings have the potential for rationality and the ability to cultivate it is a fact of human nature. But to value rationality and its subsidiary character dispositions - impartiality, intellectual discrimination, foresight, deliberation, prudence, self-reflection, self-control - is another matter entirely. -/- I am going to take it as a given that if a person's freedom to act on her impulses and gratify her desires is constrained by the existence of others' equal, or more powerful, conflicting impulses and (...)
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  37.  37
    Justice, Liberal Neutrality, and the New Genetics.Adrian M. Viens - 2005 - Journal of Philosophical Research 30 (Supplement):135-145.
  38. Jeremy Waldron, God, Locke, and Equality: Christian Foundations in Locke's Political Thought Reviewed By.Adrian M. Viens - 2004 - Philosophy in Review 24 (3):230-231.
     
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  39. Keith Graham, Practical Reasoning in a Social World: How We Act Together Reviewed By.Adrian M. Viens - 2003 - Philosophy in Review 23 (1):28-30.
     
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  40.  12
    Operation of Justice in a Public Healthcare System.Adrian M. Viens - 2001 - American Journal of Bioethics 1 (2):1c-2c.
  41.  21
    On Rawls.Adrian M. Viens - 2001 - Newsletter of the Society for the Advancement of American Philosophy 29 (89):54-55.
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  42. On Rawls: A Liberal Theory of Justice and Justification. [REVIEW]Adrian M. Viens - 2001 - Newsletter of the Society for the Advancement of American Philosophy 29 (89):54-55.
  43. Peter Baumann and Monika Betzler, Eds., Practical Conflicts: New Philosophical Essays Reviewed By.Adrian M. Viens - 2005 - Philosophy in Review 25 (3):159-161.
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  44.  18
    Prudential Motives and Reciprocal Altruism.Adrian M. Viens - 2004 - American Journal of Bioethics 4 (4):44 – 46.
  45.  24
    Marcia Lind, 1951-2000.Adrian M. S. Piper - 2001 - Proceedings and Addresses of the American Philosophical Association 75 (2):118 - 121.
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  46. Are There Levels of Consciousness?Tim Bayne, Jakob Hohwy & Adrian M. Owen - 2016 - Trends in Cognitive Sciences 20 (6):405-413.
    The notion of a level of consciousness is a key construct in the science of consciousness. Not only is the term employed to describe the global states of consciousness that are associated with post-comatose disorders, epileptic absence seizures, anaesthesia, and sleep, it plays an increasingly influential role in theoretical and methodological contexts. However, it is far from clear what precisely a level of consciousness is supposed to be. This paper argues that the levels-based framework for conceptualizing global states of consciousness (...)
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  47.  3
    Kon-Tiki Experiments.Aaron Novick, Adrian M. Currie, Eden W. McQueen & Nathan L. Brouwer - 2020 - Philosophy of Science 87 (2):213-236.
    We identify a species of experiment—Kon-Tiki experiments—used to demonstrate the competence of a cause to produce a certain effect, and we examine their role in the historical sciences. We argue that Kon-Tiki experiments are used to test middle-range theory, to test assumptions within historical narratives, and to open new avenues of inquiry. We show how the results of Kon-Tiki experiments are involved in projective inferences, and we argue that reliance on projective inferences does not provide historical scientists with any special (...)
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  48.  14
    The Dissociation Between Command Following and Communication in Disorders of Consciousness: An fMRI Study in Healthy Subjects.Natalie R. Osborne, Adrian M. Owen & Davinia Fernández-Espejo - 2015 - Frontiers in Human Neuroscience 9.
  49.  45
    Ethics of Neuroimaging After Serious Brain Injury.Charles Weijer, Andrew Peterson, Fiona Webster, Mackenzie Graham, Damian Cruse, Davinia Fernández-Espejo, Teneille Gofton, Laura E. Gonzalez-Lara, Andrea Lazosky, Lorina Naci, Loretta Norton, Kathy Speechley, Bryan Young & Adrian M. Owen - 2014 - BMC Medical Ethics 15 (1):41.
    Patient outcome after serious brain injury is highly variable. Following a period of coma, some patients recover while others progress into a vegetative state (unresponsive wakefulness syndrome) or minimally conscious state. In both cases, assessment is difficult and misdiagnosis may be as high as 43%. Recent advances in neuroimaging suggest a solution. Both functional magnetic resonance imaging and electroencephalography have been used to detect residual cognitive function in vegetative and minimally conscious patients. Neuroimaging may improve diagnosis and prognostication. These techniques (...)
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  50. Ethical Considerations in Functional Magnetic Resonance Imaging Research in Acutely Comatose Patients.Charles Weijer, Tommaso Bruni, Teneille Gofton, G. Bryan Young, Loretta Norton, Andrew Peterson & Adrian M. Owen - 2015 - Brain:0-0.
    After severe brain injury, one of the key challenges for medical doctors is to determine the patient’s prognosis. Who will do well? Who will not do well? Physicians need to know this, and families need to do this too, to address choices regarding the continuation of life supporting therapies. However, current prognostication methods are insufficient to provide a reliable prognosis. -/- Functional Magnetic Resonance Imaging (MRI) holds considerable promise for improving the accuracy of prognosis in acute brain injury patients. Nonetheless, (...)
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