Biobanking is a relatively new concept in Egypt. Building a good relationship with different stakeholders is essential for the social sustainability of biobanks. To establish this relationship, it is necessary to assess the attitude of different groups towards this concept. The objective of this work is to assess the knowledge, attitude, and opinions of Egyptian patients towards biobanking issues. We designed a structured survey to be administered to patients coming to the outpatient clinics in 3 university hospitals in Egypt. The (...) survey included questions estimating the level of knowledge about the term “Biobank”, together with questions about the attitudes and opinions about related issues. Two hundred and fifty-nine patients participated in the survey. Eighty-one percent of participants reported that they never heard about the term before. About 85% expressed that they would be willing to donate their samples for research and about 87% thought that sample donation did not contradict their religious beliefs. Fifty eight percent were willing to participate in a genetic research project, 27.8% supported sharing their sample with pharmaceutical companies, and 32.4% agreed to share their samples with institutions abroad. Although there is limited knowledge about biobanking among Egyptian patients, many had a positive attitude towards sample donation and didn’t show religious concerns against it. However, they showed concerns regarding participation in genetic research and with sharing their samples across borders or with pharmaceutical companies. Public education about biobanking is possible, taking into consideration the specific cultural and legal framework in Egypt. (shrink)
BackgroundBiobanks have recently been established in several low- and middle-income countries in the Arab region of the Middle East. We aimed to explore the views of biobank managers regarding the challenges, ethical issues, and governance arrangements of their biobanks.MethodsIn-depth semi-structured qualitative interviews were conducted with a purposive sample of eight biobank managers from Egypt, Jordan, and Sudan. Interviews were performed either face-to-face, by phone, or via Zoom and lasted approximately 45–75 min. After verbal consent, interviews were recorded and then transcribed. (...) The authors performed a thematic analysis of the transcripts independently and then integrated the themes via a consensus process.ResultsBiobank managers discussed the main challenges in establishing their biobanks. These included the staff’s lack of experience and training, limited funds, deficit awareness of biobanks, obtaining funding from different sources. Only four reported they were active in distributing biospecimens and health data to researchers. Six biobanks used a broad consent model, one used tiered consent, and another allowed participants to opt-out of being recontacted. Five managers avoided partnerships with pharmaceutical companies due to concerns with unfavorable reactions from the community. Five managers did not have clear policies for returning research results to the donors. Five expressed challenges with sample and data sharing with international collaborators; all five used material transfer agreements. The biobank managers revealed variable governance arrangements and activities with community involving awareness and educational efforts rather than active engagement. Several expressed the importance of transparency with the operations of their biobanks and gaining the trust of their stakeholders.ConclusionManagers of biobanks in LMICs in the Arab Middle East encounter financial, operational, and social challenges toward their sustainability efforts. Discussions with key stakeholders are warranted to manage ethical issues involving informed consent, privacy, data sharing, and the return of results. We recommend that biobank managers in the Arab Middle East form collaborative networks within the region and internationally, develop trusting governance relationships with their stakeholders, and pursue engagement activities with their communities to enhance trust. (shrink)
Population-based genomics studies have proven successful in identifying genetic variants associated with diseases. High-quality biospecimens linked with informative health data from diverse segments of the population have made such research possible. However, the success of biobank research depends on the willingness of the public to participate in this type of research. We aimed to explore the factors associated with the willingness of the public to participate in biobank research from four low- and middle-income countries in the Arab region (Egypt, Jordan, (...) Morocco, and Sudan). We used a previously validated questionnaire to assess several constructs that included the public’s perceptions, attitudes, and willingness to participate in biobank research. We recruited 967 participants. More than half did not have prior awareness of biobanks. Participants’ willingness to donate biospecimens and health data was less than 10%. Our results also showed that participants harbored concerns with trust, privacy, and with data-sharing involving international researchers. Predictors of willingness to participate in biobank research included no previous involvement in research and positive attitudes toward biobanks. Finally, our study showed several differences between the four countries regarding several of the investigated constructs. We conclude there should be additional efforts to raise public awareness and enhance perceptions of the public in biobanking research to enhance trust. We further recommend qualitative research to explore the underlying factors that contribute to the public’s concerns with international data sharing that would enhance global health. (shrink)
Arif Ahmed’s paper claims moral neutrality for game theory. This is not true, however, of much of classical game theory, for example Ken Binmore’s Game Theory and the Social Contract. The field has changed comparatively recently. With respect to his own version, he claims that evolutionary explanation of cooperation is incompatible with theism, but this is because he thinks just about anything is compatible with it. It is important to see that this critique is the same as the logical (...) positivists’ critique in the 1950s, for example in Antony Flew’s parable of the invisible gardener. The logical positivists thought that a statement could only be meaningful if it is either a tautology or empirically verifiable or falsifiable. But a claim that God exists is not subject to empirical confirmation, because God is not that kind of being. To dismiss the claim on that basis is just to beg the question. (shrink)
ABSTRACTAdopting a temporally distant perspective on stressors reduces distress in adults. Here we investigate whether the extent to which individuals project themselves into the future influences distancing efficacy. We also examined modulating effects of age across adolescence and reactive aggression: factors associated with reduced future-thinking and poor emotion regulation. Participants read scenarios and rated negative affect when adopting a distant-future perspective, near-future perspective, or when reacting naturally. Self-report data revealed significant downregulation of negative affect during the distant-future condition, with a (...) similar though non-significant skin conductance pattern. Importantly, participants who projected further ahead showed the greatest distress reductions. While temporal distancing efficacy did not vary with age, participants reporting greater reactive aggression showed reduced distancing efficacy, and projected themselves less far into the future. Fi... (shrink)
ABSTRACTEvidence is currently mixed regarding the way in which cognitive conflict modulates the effect of emotion on task performance. The present study aimed to address methodological differences...
Frequent itemset mining is the most important step of association rule mining. It plays a very important role in incremental data environments. The massive volume of data creates an imminent need to design incremental algorithms for the maximal frequent itemset mining in order to handle incremental data over time. In this study, we propose an incremental maximal frequent itemset mining algorithms that integrate subjective interestingness criterion during the process of mining. The proposed framework is designed to deal with incremental data, (...) which usually come at different times. It extends FP-Max algorithm, which is based on FP-Growth method by pushing interesting measures during maximal frequent itemset mining, and performs dynamic and early pruning to leave uninteresting frequent itemsets in order to avoid uninteresting rule generation. The framework was implemented and tested on public databases, and the results found are promising. (shrink)
In this paper, I aim to articulate, at least in part, what makes Sara Ahmed’s uses and analyses of metaphors fruitful for thinking about problems in the social world. I argue that Ahmed’s these metaphorical concepts perform three functions. First, her analyses improve our understanding of the social world precisely because we already understand the world through metaphors. They draw out the metaphors we use to think about ourselves and others and, in doing so, allow us to think (...) more carefully about those metaphors. To support this claim, I will draw on the insights of George Lakoff and Mark Johnson in their seminal Metaphors We Live By. Second, one thing that Ahmed’s analyses of metaphors often allow us to see is that the movement and arrangement of bodies in the social world can be analyzed in poetic terms. To be clear, it is not just that we linguistically express and understand bodies through metaphor, metonymy, synecdoche, and the like, but also that the movement, arrangement, and reactions of our bodies are themselves experienced as metaphorical and metonymical, and that they provide the foundation for understanding social reality in metaphorical terms. Finally, as a result of the first two functions, Ahmed helps us imagine ways to intervene so that we can change how we live and interact with others. Specifically, to work toward positive social change, we might both rework the metaphorical concepts we use to understand the social world and alter our practices of movement that, all too often, reify existing social boundaries and inequalities. (shrink)
Errors have been the concern of providers and consumers of health care services. However, consumers' perception of medical errors in developing countries is rarely explored. The aim of this study is to assess community members' perceptions about medical errors and to analyse the factors affecting this perception in one Middle East country, Oman.
This article explores Leila Ahmed’s A Border Passage, and Nawal El Saadawi’s Memoirs from the Women’s Prison, A Daughter of Isis, and Walking Through Fire. It contrasts their works and argues that location and genderawareness play an important role in the writing of autobiographies. The focus is on showing how El Saadawi’s positioning as a feminist activist in Egypt and Ahmed’s location in the USA determine the texts’ themes and shape the construction of the autobiographical “I.”.
BackgroundA different ethos with respect to the perception of medical ethics prevails in societies in transition such as those in the Arabian Peninsula, which makes it difficult to apply international principles of bioethics in medical practice. This study aimed to develop and psychometrically test an instrument that measures physicians’ awareness of bioethics and medical law and their attitudes towards the practice of medical ethics. Additionally, it examined physician correlates influencing the awareness of bioethics.MethodsFollowing a rigorous review of relevant literature by (...) a panel of experts, a 13-item instrument, the Omani physicians’ bioethics and medical law awareness questionnaire was developed with the aim of assessing physicians’ awareness of bioethics and medical law. The study tool’s construct validity and internal consistency reliability were examined by exploratory factor analysis and Cronbach’s alpha. In a cross-sectional study, the questionnaire was distributed among a random sample of 200 physicians at a tertiary hospital in Muscat, Oman. Participant characteristics that may influence awareness of bioethics and medical law were explored.ResultsThe EFA of the OBMLA questionnaire resulted in three well-loading factors: Physicians’ bioethics practice subscale incentive related bioethics subscale and medical law awareness subscale. Internal consistency reliability ranged between Cronbach’s α: 0.73–0.8. Of the total 200 participants, 52% reported that teaching medical ethics during medical school was inadequate. The overall mean of the bioethics awareness score and Omani medical law awareness were 27.6 and 10.1 respectively. The majority of physicians reported that they frequently encountered ethical dilemmas in their practice and 24.5% endorsed the view that unethical decisions tended to occur in their practice.ConclusionThe study provides an insight into the practice of bioethics, and the awareness of bioethics and medical law among physicians in a teaching hospital in Oman. The OBMLA questionnaire appears to be a valid and reliable tool to assess a physician’s awareness of bioethics and medical law. In this preliminary study, it appears that participants have suboptimal scores on the indices which measure practice and awareness of bioethics and medical law. (shrink)
Abstract: Background: In spite of the fact that computers continue to improve in speed and functions operation, they remain complex to use. Problems frequently happen, and it is hard to resolve or find solutions for them. This paper outlines the significance and feasibility of building a desktop PC problems diagnosis system. The system gathers problem symptoms from users’ desktops, rather than the user describes his/her problems to primary search engines. It automatically searches global databases of problem symptoms and solutions, and (...) also allows ordinary users to contribute exact problem reports in a structured manner. Objectives: The main goal of this Knowledge Based System is to get the suitable problem desktop PC symptoms and the correct way to solve the errors. Methods: In this paper the design of the proposed Knowledge Based System which was produced to help users of desktop PC in knowing many of the problems and error such as : Power supply problems, CPU errors, RAM dumping error, hard disk errors and bad sectors and suddenly restarting PC. The proposed Knowledge Based System presents an overview about desktop PC hardware errors are given, the cause of fault are outlined and the solution to the problems whenever possible is given out. CLIPS Knowledge Based System language was used for designing and implementing the proposed expert system. Results: The proposed PC desktop troubleshooting Knowledge Based System was evaluated by IT students and they were satisfied with its performance. (shrink)
Buildings energy consumption is growing gradually and put away around 40% of total energy use. Predicting heating and cooling loads of a building in the initial phase of the design to find out optimal solutions amongst different designs is very important, as ell as in the operating phase after the building has been finished for efficient energy. In this study, an artificial neural network model was designed and developed for predicting heating and cooling loads of a building based on a (...) dataset for building energy performance. The main factors for input variables are: relative compactness, roof area, overall height, surface area, glazing are a, wall area, glazing area distribution of a building, orientation, and the output variables: heating and cooling loads of the building. The dataset used for training are the data published in the literature for various 768 residential buildings. The model was trained and validated, most important factors affecting heating load and cooling load are identified, and the accuracy for the validation was 99.60%. (shrink)
We give a new characterization of the class of completely representable cylindric algebras of dimension 2 < n ≤ ω via special neat embeddings. We prove an independence result connecting cylindric algebra to Martin's axiom. Finally we apply our results to finite-variable first order logic showing that Henkin and Orey's omitting types theorem fails for $L_{n}$, the first order logic restricted to the first n variables when 2 < n < ω. $L_{n}$ has been recently studied as a many-dimensional modal (...) logic. (shrink)
The study aimed at measuring the dominant pattern of leadership and its relation to the performance of the administrative staff in the Palestinian universities. The study community consists of all the administrative staff from Al-Azhar University and the Islamic University, and through the census of the study society it was found to consist of (655) administrative staff. In order to achieve the objectives of the study, the researchers used the method of random sample in the study, and the study was (...) conducted on a sample of (221) administrative staff of the surveyed universities and the response rate was (82.35%). The study found that there is a high degree of satisfaction with the Dominant Pattern of Leadership in the Palestinian universities in Gaza Strip from the point of view of the administrative staff, which reached (71.67%). There is a high level of performance from the point of view of administrative staff, with a percentage of (82.53%). There is a direct correlation between the dominant pattern of leadership and the functional Performance of Administrative Staff, the absence of differences between the sample according to the gender variable in their perception of the dominant pattern of leadership and the functional Performance of Administrative Staff, the absence of differences in the perception of employees of the dominant pattern of leadership and the functional Performance of Administrative Staff depending on the age variable. There are differences of statistical significance according to the variable of scientific qualification in the Dominant Pattern of Leadership, while there were no differences in performance, the differences in the dominant pattern of leadership according to the scientific qualification were in favor of those who obtained the diploma degree compared to other practical qualifications, the absence of differences in the perception of employees of the dominant pattern of leadership and the functional Performance of Administrative Staff depending on the variable years of service, the absence of differences in the perception of employees of the dominant pattern of leadership and the functional Performance of Administrative Staff depending on the variable level of career (Director, Head of Department, and Administrative Officer). There were differences in the perception of workers to the dominant pattern of leadership depending on the variable of the workplace, where there were differences in favor of workers in deanships and colleges compared with the workers in the technical departments. While there were no differences in job performance according to the workplace variable, the existence of differences in the perception of workers to the dominant pattern of leadership depending on the university in which they work in favor of the Islamic University and the absence of differences in performance between the Islamic University and Al-Azhar University. The study reached a number of recommendations, the most important of which is that the interest of the managements of the Palestinian universities in improving the dominant pattern of leadership, to give universities the opportunity to participate in decision-making, the continued administration of universities interest and continuous improvement of the performance of its employees, enhance the periodic evaluation of job performance and to inform employees and express their opinion, solving workers' problems and giving them the opportunity to contribute to solving their own problems, the use of the staff rotation method periodically and strengthening the democratic the dominant pattern of leadership and empowering university staff. -/- . (shrink)
The study aimed to know the relationship between the nature of the work and the type of communication among the Employees in the Palestinian universities. A comparative study between Al-Azhar University and Al-Aqsa University. The researchers used the analytical descriptive method through a questionnaire that is randomly distributed among the employees of Al-Azhar and Al-Aqsa universities in Gaza Strip. The study was conducted on a sample of (176) administrative employees from the surveyed universities. The response rate was (85.79%). The study (...) reached a number of results, the most important of which is that there is a high degree of satisfaction with the nature of work prevailing in the Palestinian universities in Gaza Strip from the point of view of the administrative staff, where the percentage was (68.15%). There is an Mean level of communication from the point of view of administrative staff, with a percentage of (67.50%). There is a direct correlation between the nature of the work and the prevailing pattern of communication. There is an absence of differences between the sample according to the gender variable in their perception of the nature of work and the prevailing pattern of communication. There is an absence of differences in the perception of Employees nature of work and the pattern of communication prevailing depending on the variables (age, years of service, job level, and university). There are statistically significant differences between Al-Azhar University and Al-Aqsa University in favor of Al-Azhar University. The study reached a number of recommendations, the most important of which is that the interest of the management of the Palestinian universities in Gaza Strip in general, and Al-Aqsa and Al-Azhar Universities in particular should be provided with a good nature of work and communication. There is a need for continuing the management of universities to pay attention and continuous improvement of the performance of employees. There is an importance of solving the problems of Employees and giving them the opportunity to contribute to solving their own problems. Staff rotation should be used periodically and the need to strengthen the democratic leadership style and empower university Employees. (shrink)
Tuberculosis is caused by bacillus Mycobacterium tuberculosis. In this study, a mathematical model of tuberculosis is analyzed. The numerical behaviour of the considered model is analyzed including basic reproduction number and stability. We applied three numerical techniques to this model, i.e., nonstandard finite difference scheme, Runge–Kutta method of order 4, and forward Euler scheme. NSFD scheme preserves all the essential properties of the model. Acquired results corroborate that NSFD scheme converges for each step size. While the other two schemes failed (...) to preserve some properties of the model such as positivity and convergence. A graphical comparison presented in this study confirms the numerical stability of the NSFD technique shown here is maintained over a large area. (shrink)
Despite the persistence of the theoretical model of the cathartic theory in psychoanalysis, it is not what we practice clinically. Freud’s Other Theory of Psychoanalysis deals with eliciting that other unarticulated theory from the Freudian text to replace the catharsis theory and open the theoretical impasse it created.
In a recent article, Sara Ahmed castigates so-called new materialist theorists for their accusations of a biophobia evident in feminism. Biophobia is taken simply to be the claim that feminists do not engage with biological detail in their theorizations, which is demonstrably not the case. However, an elaboration of new materialist usage of biophobia reveals that they are proposing a particular conceptualization of what an engagement with the biological means. They theorize an entanglement and non-separability of the biological with/in (...) sociality, and what they criticize in much feminism is the conventional assumption that the biological and the social are two separate and discrete systems that then somehow interact. If the new materialist arguments are fully contextualized and then applied to the supporting examples given in the article, the new materialist critique is actually borne out. (shrink)
Published in 1953, Wittgenstein's Philosophical Investigations had a deeply unsettling effect upon our most basic philosophical ideas concerning thought, sensation, and language. Its claim that philosophical questions of meaning necessitate a close analysis of the way we use language continues to influence Anglo-American philosophy today. However, its compressed and dialogic prose is not always easy to follow. This collection of essays deepens but also challenges our understanding of the work's major themes, such as the connection between meaning and use, the (...) nature of concepts, thought and intentionality, and language games. Bringing together leading philosophers and Wittgenstein scholars, it offers a genuinely critical approach, developing new perspectives and demonstrating Wittgenstein's relevance for contemporary philosophy. This volume will appeal to readers interested in the later Wittgenstein, in addition to those interested in the philosophy of language, the philosophy of mind, metaphysics and epistemology. (shrink)
Published in 1953, Wittgenstein's Philosophical Investigations had a deeply unsettling effect upon our most basic philosophical ideas concerning thought, sensation and language. Its claim that philosophical questions of meaning necessitate a close analysis of the way we use language continues to influence Anglo-American philosophy today. However, its compressed and dialogic prose is not always easy to follow. This collection of essays deepens but also challenges our understanding of the work's major themes, such as the connection between meaning and use, the (...) nature of concepts, thought and intentionality, and language games. Bringing together leading philosophers and Wittgenstein scholars, it offers a genuinely critical approach and demonstrating Wittgenstein's relevance for contemporary philosophy. This volume will appeal to readers interested in the later Wittgenstein, in addition to those interested in the philosophy of language, the philosophy of mind, metaphysics and epistemology. (shrink)
The overall policy and strategies of an organization i.e. employeepolicy or employee development strategies, resource management as well asmonitoring and control strategies characteristically have an effect on the qualitymanagement of the organization. These policies usually also have impact onthe stakeholders i.e. satisfaction of the wider community and employees ofthe particular organization. The aim of this paper is to examine the policyand strategies of the Chittagong City Corporation for quality improvementand how these policy and strategies impact on the needs of its (...) stakeholders.This paper is guided by the EFQM model as the theoretical underpinning thatprovides specific enabler criteria of quality management of organizations suchas employee policy, development of partnerships and resource management,and the monitoring of strategies. These enabler criteria help to explain the waysin which total quality management is implemented in any organization.Data for this study was collected from a total of 142 participants, includingselective officials of the Chittagong City Corporation, city dwellers,government officials and civil society representatives by using a structuredquestionnaire. The findings of this study reveal that the CCC has failed toconvey clearly its quality mission and objectives to its employees at all levels. (shrink)
We give a new characterization of the class of completely representable cylindric algebras of dimension 2 #lt; n w via special neat embeddings. We prove an independence result connecting cylindric algebra to Martin''s axiom. Finally we apply our results to finite-variable first order logic showing that Henkin and Orey''s omitting types theorem fails for L n, the first order logic restricted to the first n variables when 2 #lt; n#lt;w. L n has been recently (and quite extensively) studied as a (...) many-dimensional modal logic. (shrink)
In What's the Use? Sara Ahmed continues the work she began in The Promise of Happiness and Willful Subjects by taking up a single word--in this case, use--and following it around. She shows how use became associated with life and strength in nineteenth century biological and social thought and considers how utilitarianism offered a set of educational techniques for shaping individuals by directing them toward useful ends. Ahmed also explores how spaces become restricted to some uses and users (...) with specific reference to universities. She notes, however, the potential for queer use: how things can be used in ways that were not intended or by those for whom they were not intended. Ahmed posits queer use as way of reanimating the project of diversity work as the ordinary and painstaking work of opening up institutions to those who have historically been excluded from them. (shrink)
In this paper an Artificial Neural Network (ANN) model was used to help cars dealers recognize the many characteristics of cars, including manufacturers, their location and classification of cars according to several categories including: Buying, Maint, Doors, Persons, Lug_boot, Safety, and Overall. ANN was used in forecasting car acceptability. The results showed that ANN model was able to predict the car acceptability with 99.12 %. The factor of Safety has the most influence on car acceptability evaluation. Comparative study method is (...) suitable for the evaluation of car acceptability forecasting, can also be extended to all other areas. (shrink)
Newcomb's Problem is a controversial paradox of decision theory. It is easily explained and easily understood, and there is a strong chance that most of us have actually faced it in some form or other. And yet it has proven as thorny and intractable a puzzle as much older and better-known philosophical problems of consciousness, scepticism and fatalism. It brings into very sharp and focused disagreement several long-standing philosophical theories on practical rationality, on the nature of free will, and on (...) the direction and analysis of causation. This volume introduces readers to the nature of Newcomb's Problem, and ten chapters by leading scholars present the most recent debates around the Problem and analyse its ramifications for decision theory, metaphysics, philosophical psychology and political science. Their chapters highlight the status of Newcomb's Problem as a live and continuing issue in modern philosophy. (shrink)