To prepare for potential human infection challenge studies involving SARS-CoV-2, we convened a multidisciplinary working group to address ethical questions regarding whether and how much SAR...

The peer commentaries on our Target Article, “Promoting Ethical Payment in Human Infection Challenge Studies,” offer a number of insights that will help advance the co...

Volume 20, Issue 9, September 2020, Page 33-36.

Intersectionality has become a significant intellectual approach for those thinking about the ways that race, gender, and other social identities converge in order to create unique forms of oppression. Although the initial work on intersectionality addressed the unique position of black women relative to both black men and white women, the concept has since been expanded to address a range of social identities. Here we consider how to apply some of the theoretical tools provided by intersectionality to the clinical context. (...) We begin with a brief discussion of intersectionality and how it might be useful in a clinical context. We then discuss two clinical scenarios that highlight how we think considering intersectionality could lead to more successful patient–clinician interactions. Finally, we extrapolate general strategies for applying intersectionality to the clinical context before considering objections and replies. (shrink)

Thomas Jefferson is among the most important and controversial of American political thinkers: his influence (libertarian, democratic, participatory, and agrarian-republican) is still felt today. A prolific writer, Jefferson left 18,000 letters, Notes on the State of Virginia, an Autobiography, and numerous other papers. Joyce Appleby and Terence Ball have selected the most important of these for presentation in the Cambridge Texts series: Jefferson's views on topics such as revolution, self-government, the role of women and African-American and Native (...) Americans emerge to give a fascinating insight into a man who owned slaves, yet advocated the abolition of slavery. The texts are supported by a concise introduction, suggestions for further reading and short biographies of key figures, all providing invaluable assistance to the student encountering the breadth and richness of Jefferson's thought for the first time. (shrink)

This important and comprehensive work of 18th-century Islamic religious thought written in Arabic by a pre-eminent South Asian scholar provides an extensive and detailed picture of Muslim theology and interpretive strategies on the eve of the modern period.

Believing that p, assuming that p, and imagining that p involve regarding p as true—or, as we shall call it, accepting p. What distinguishes belief from the other modes of acceptance? We claim that conceiving of an attitude as a belief, rather than an assumption or an instance of imagining, entails conceiving of it as an acceptance that is regulated for truth, while also applying to it the standard of being correct if and only if it is true. We argue (...) that the second half of this claim, according to which the concept of belief includes a standard of correctness, is required to explain the fact that the deliberative question whether to believe that p is transparent to the question whether p. This argument raises various questions. Is there such a thing as deliberating whether to believe? Is the transparency of the deliberative question whether to believe that p the same as the transparency of the factual question whether I do believe that p? We will begin by answering these questions and then turn to a series of possible objections to our argument. (shrink)

Why, when asking oneself whether to believe that p, must one immediately recognize that this question is settled by, and only by, answering the question whether p is true? Truth is not an optional end for first-personal doxastic deliberation, providing an instrumental or extrinsic reason that an agent may take or leave at will. Otherwise there would be an inferential step between discovering the truth with respect to p and determining whether to believe that p, involving a bridge premise that (...) it is good (in whichever sense of good one likes, moral, prudential, aesthetic, allthings-considered, etc.) to believe the truth with respect to p. But there is no such gap between the two questions within the first-personal deliberative perspective; the question whether to believe that p seems to collapse into the question whether p is true. (shrink)

Why, when asking oneself whether to believe that p, must one immediately recognize that this question is settled by, and only by, answering the question whether p is true? Truth is not an optional end for first-personal doxastic deliberation, providing an instrumental or extrinsic reason that an agent may take or leave at will. Otherwise there would be an inferential step between discovering the truth with respect to p and determining whether to believe that p, involving a bridge premise that (...) it is good to believe the truth with respect to p. But there is no such gap between the two questions within the first-personal deliberative perspective; the question whether to believe that p seems to collapse into the question whether p is true. (shrink)

This experiment investigated the effect of format (line vs. bar), viewers’ familiarity with variables, and viewers’ graphicacy (graphical literacy) skills on the comprehension of multivariate (three variable) data presented in graphs. Fifty-five undergraduates provided written descriptions of data for a set of 14 line or bar graphs, half of which depicted variables familiar to the population and half of which depicted variables unfamiliar to the population. Participants then took a test of graphicacy skills. As predicted, the format influenced viewers’ interpretations (...) of data. Specifically, viewers were more likely to describe x–y interactions when viewing line graphs than when viewing bar graphs, and they were more likely to describe main effects and “z–y” (the variable in the legend) interactions when viewing bar graphs than when viewing line graphs. Familiarity of data presented and individuals’ graphicacy skills interacted with the influence of graph format. Specifically, viewers were most likely to generate inferences only when they had high graphicacy skills, the data were familiar and thus the information inferred was expected, and the format supported those inferences. Implications for multivariate data display are discussed. (shrink)

George, feeling stressed and anxious about the criminal investigation into his firm’s accounting practices, decides that it would do him good to get away and take a long, relaxing vacation in Bermuda. According to popular informed-desire accounts of a person’s good, if George would desire to take a vacation to Bermuda upon being made fully aware of what his experience of the vacation would be like and of all the consequences therein, then this course of action would benefit him. This (...) does not mean that George must actually be privy to whether his fully informed self would desire to travel to Bermuda, but whether he would, according to such an account, determines whether going to Bermuda would benefit George, whether he or anyone else is capable of knowing it. (shrink)

I defend an instrumentalist account of moral responsibility and adopt Manuel Vargas’ idea that our responsibility practices are justified by their effects. However, whereas Vargas gives an independent account of morally responsible agency, on my account, responsible agency is defined as the susceptibility to developing and maintaining moral agency through being held responsible. I show that the instrumentalism I propose can avoid some problems more crude forms of instrumentalism encounter by adopting aspects of Strawsonian accounts. I then show the implications (...) for our understanding of responsibility: my account requires us to adopt a graded notion of responsibility and accept the claim that certain individuals may not be responsible because they are not susceptible to being influenced by our moral responsibility practices. Finally, I discuss whether the account is committed to allowing the instrumentalization of non-responsible individuals in cases where blaming them may benefit others’ moral agency. (shrink)

Research teams have made considerable progress in treating absolute uterine factor infertility through uterus transplantation, though studies have differed on the choice of either deceased or living donors. While researchers continue to analyze the medical feasibility of both approaches, little attention has been paid to the ethics of using deceased versus living donors as well as the protections that must be in place for each. Both types of uterus donation also pose unique regulatory challenges, including how to allocate donated organs; (...) whether the donor / donor's family has any rights to the uterus and resulting child; how to manage contact between the donor / donor's family, recipient, and resulting child; and how to track outcomes moving forward. (shrink)

Thomas Jefferson’s argument against long-term debt and his theory of usufruct are used to show why each generation is obligated to protect the independence of future generations. This argument forms the theory of “Jeffersonian generational independence.” The theory has wide implications for the environmental movement because most environmental problems result in limitations on the liberty of future generations. I compare and defend Jeffersonian generational independence from two alternatives including the investment theory raised by James Madison and the problem of (...) generational interdependence raised by John Passmore or Edmund Burke. When the obligation to protect the independence of future generations is taken seriously, liberalism can no longer reasonably be used to defend environmental exploitation, since such exploitation amounts to an attack on the liberty and independence which form its core values. (shrink)

In this paper, I address the question whether mental disorders should be understood to be brain disorders and what conditions need to be met for a disorder to be rightly described as a brain disorder. I defend the view that mental disorders are autonomous and that a condition can be a mental disorder without at the same time being a brain disorder. I then show the consequences of this view. The most important of these is that brain differences underlying mental (...) disorders derive their status as disordered from the fact that they realize mental dysfunction and are therefore non-autonomous or dependent on the level of the mental. I defend this view of brain disorders against the objection that only conditions whose pathological character can be identified independently of the mental level of description count as brain disorders. The understanding of brain disorders I propose requires a certain amount of conceptual revision and is at odds with approaches which take the notion of brain disorder to be fundamental or look to neuroscience to provide us with a purely physiological understanding of mental illness. It also entails a pluralistic understanding of psychiatric illness, according to which a condition can be both a mental disorder and a brain disorder. (shrink)

The subject matter of this paper is the view that it is correct, in an absolute sense, to believe a proposition just in case the proposition is true. I take issue with arguments in support of this view put forward by Nishi Shah and David Velleman.

Shah ʿAbbas: The King who Refashioned Iran By QuinnSholeh A., xvii + 142 pp. Price HB £30.00. EAN 978–1851684250.

The question of whether psychopaths are criminally and morally responsible has generated significant controversy in the literature. In this paper, we discuss what relevance a psychopathy diagnosis has for criminal responsibility. It has been argued that figuring out whether psychopathy is a mental illness is of fundamental importance, because it is a precondition for psychopaths’ eligibility to be excused via the legal insanity defense. But even if psychopathy counts as a mental illness, this alone is not sufficient to show the (...) insanity defense is applicable; it must also be shown that, as a result of the illness, specific deficits in moral understanding or control are present. In this paper, we show that a diagnosis of psychopathy will generally not indicate that a defendant is eligible for an insanity defense. This is because the group of individuals subsumed under the diagnosis is so heterogeneous that while some psychopaths do show significant impairments in affect and control which may impact on their responsibility, many psychopaths are not incapacitated in a way relevant to responsibility. (shrink)

This paper contributes to the debate over the so-called “easy argument for numbers”, an argument that uses evidence from natural language to support the metaphysically significant claim that numbers exist. It presents novel data showing that critical examples in the literature are ambiguous between two readings, contrary to previous assumptions. It then accounts for these data using independently motivated linguistic theory. The account developed rescues the easy argument from the primary challenges leveled against it in the literature and sets the (...) agenda for future work to determine whether or not the argument is valid. (shrink)

When we deliberate whether to believe some proposition, we feel immediately compelled to look for evidence of its truth. Philosophers have labelled this feature of doxastic deliberation 'transparency'. I argue that resolving the disagreement in the ethics of belief between evidentialists and pragmatists turns on the correct explanation of transparency. My hypothesis is that it reflects a conceptual truth about belief: a belief that p is correct if and only if p. This normative truth entails that only evidence can be (...) a reason for belief. Although evidentialism does not follow directly from the mere psychological truth that we cannot believe for non-evidential reasons, it does follow directly from the normative conceptual truth about belief which explains why we cannot do so. (shrink)

Slippery slope arguments are frequently dismissed as fallacious or weak arguments but are nevertheless commonly used in political and bioethical debates. This paper gives an overview of different variants of the argument commonly found in the literature and addresses their argumentative strength and the interrelations between them. The most common variant, the empirical slippery slope argument, predicts that if we do A, at some point the highly undesirable B will follow. I discuss both the question which factors affect likelihood of (...) slippage and the relation between the strength of the prediction and the justificatory power of the argument. (shrink)

Current formal dialectical models postulate normative rules that enable discussants to conduct dialogical interactions without committing fallacies. Though the rules for conducting a dialogue are supposed to apply to interactions between actual arguers, they are without exception theoretically motivated. This creates a gap between model and reality, because dialogue participants typically leave important content-related elements implicit. Therefore, analysts cannot readily relate normative rules to actual debates in ways that will be empirically confirmable. This paper details a new, data-driven method for (...) describing discussants’ actual reply structures, wherein corpus studies serve to acknowledge the complexity of natural argumentation. Rather than refer exclusively to propositional content as an indicator of arguing pro/contra a given claim, the proposed approach to dialogue structure tracks the sequence of dialogical moves itself. This arguably improves the applicability of theoretical dialectical models to empirical data, and thus advances the study of dialogue systems. (shrink)

From the start, Americans were wrestling with the proper connections between "private and public felicity." On its face, the first line of the First Amendment to the Constitution seems to settle the issue: "Congress shall make no law respecting the establishment of religion or prohibiting the free exercise thereof." Thomas Jefferson declared that this provision "buil[t] a wall of separation between church and state." While the proscription against meddling with religion originally applied only to the national government, the Fourteenth (...) Amendment extended the Constitution—and, in theory, Jefferson's wall—to the state governments. But the Constitution is just the start of the story. America's boisterous, protean religious life sends waves of fervor breaking against Jefferson's wall. Religious fervor provokes moralistic attitudes that filter through American politics. This paper examines the reach of this moralizing effect with a glance at two very unlikely—that is, apparently secular—policy domains: health care and jails. (shrink)

Allocating access to unapproved COVID-19 drugs available via Pre-Approval Access pathways or Emergency Use Authorization raises unique challenges at the intersection of clinical care and research....

A collection of late 20th-century scholarship devoted to Thomas Jefferson as a politician, writer, philosopher, Christian and economist.

This paper examines how the latest mega plan and the Belt and Road Initiative will impact the geopolitics of energy and infrastructural development. With a massive change in the supply and demand of global energy and its infrastructure, the transition of international energy order is in the making. While the US is going towards a more isolationist path from its traditional superpower role, there are rising economies such as China, India, Japan, and Russia which are undoubtedly playing a vital role (...) in the geopolitical stage and the other development endeavors. Several regions such as Central Asia, the Arctic, Eastern Mediterranean, and the South China Sea are offering substantial natural gas and oil reserves and drawing global attention to develop energy cooperation. This situation is profoundly influencing the transition of energy order. In this transition, BRI is supposed to play an important role. As a mega development strategy with a robust geostrategic dimension, it purposes to advocate interconnectivity collaboration in framework, exchange, and advancement among the partaking nations. This super arrangement offers a lot of ventures, foundation developments, and modern reconciliation in the energy sector. The country is trying to establish a multilateral platform for endorsing and shielding energy cooperation under BRI. This paper, therefore, attempts to observe how this mega plan will contribute to reshaping the existing energy order as well as the geopolitics of energy with motivation on multifaceted energy collaboration. (shrink)

Opponents of biomedical enhancement frequently adopt what Allen Buchanan has called the “Personal Goods Assumption.” On this assumption, the benefits of biomedical enhancement will accrue primarily to those individuals who undergo enhancements, not to wider society. Buchanan has argued that biomedical enhancements might in fact have substantial social benefits by increasing productivity. We outline another way in which enhancements might benefit wider society: by augmenting civic virtue and thus improving the functioning of our political communities. We thus directly confront critics (...) of biomedical enhancement who argue that it will lead to a loss of social cohesion and a breakdown in political life. (shrink)

Volume 20, Issue 6, June 2020, Page 17-19.

The history of the National News Council's creation and demise demonstrates that there are well?grounded rationales in social vision between those who supported the concept of the NNC and those who believe its etablishment was ill?founded. This article suggests that the root of the NNC controversy lies in the differences between Madison and Jefferson's perspectives on the place of information in society. Madison and Jefferson's view on press freedom and responsibility may be as important to the debate about (...) the NNC's status as the more frequently cited pragmatic considerations such as the Council's infrastructure or management. The philosophic issues raised here are ethical at base, and should be considered by critics contemplating vehicles for media accountability. (shrink)

A collection of essays and lectures from Henry Steele Commager, one of America's eminent historians. The focus is on the age of enlightenment, with particular attention to Thomas Jefferson, and how enlightenment philosophy shaped the birth of the United States.

Dissolution of tradition : the new affiliation -- Jefferson's communitarianism : in search of the affiliated man -- Consequences of communitarianism : the other side of love.

Thomas Jefferson and Philosophy: Essays on the Philosophical Cast of Jefferson’s Writings is a collection of essays on topics that relate to philosophical aspects of Jefferson’s thinking over the years. Much historical insight is given to ground the various philosophical strands in Jefferson’s thought and writing on topics such as political philosophy, moral philosophy, slavery, republicanism, wall of separation, liberty, educational philosophy, and architecture.