Music-based interventions (MBI) have become increasingly widely adopted for dementia and related disorders. Previous research shows that music engages reward-related regions through functional connectivity with the auditory system, but evidence for the effectiveness of MBI is mixed in older adults with mild cognitive impairment (MCI) and Alzheimer’s disease (AD). This underscores the need for a unified mechanistic understanding to motivate MBIs. The main objective of the present study is to characterize the intrinsic connectivity of the auditory and reward systems in (...) healthy aging individuals with MCI, and those with AD. Using resting-state fMRI data from the Alzheimer’s Database Neuroimaging Initiative, we tested resting-state functional connectivity within and between auditory and reward systems in older adults with MCI, AD, and age-matched healthy controls (N = 105). Seed-based correlations were assessed from regions of interest (ROIs) in the auditory network (i.e., anterior superior temporal gyrus, posterior superior temporal gyrus, Heschl’s Gyrus), and the reward network (i.e., nucleus accumbens, caudate, putamen, and orbitofrontal cortex). AD individuals were lower in both within-network and between-network functional connectivity in the auditory network and reward networks compared to MCI and controls. Furthermore, graph theory analyses showed that the MCI group had higher clustering and local efficiency than both AD and control groups, whereas AD individuals had lo... (shrink)

Seit dem 2. nachchristlichen Jahrhundert werden die Schriften von Aristoteles kommentiert. Diese Ausgabe enthält griechische Kommentare zu seinem Werk vom 3. bis 8. Jahrhundert n. Chr., u. a. von Alexander von Aphrodiensias, Themistios, Joh. Philoponus, Simplicius in griechischer Sprache.

It is argued that Weyl’s theory of gravitation and electricity came out of ‘mathematical justice’: out of the equal rights direction and length. Such mathematical justice was manifestly at work in the context of discovery, and is enough to derive all of source-free electromagnetism. Weyl’s repeated references to coordinates and gauge are taken to express equal treatment of direction and length.

This chapter contains sections titled: Introduction Necessity and Essence Naming and Reference Rules and Meaning Conclusion References.

Can we have a posteriori knowledge of modal facts? And if so, is that knowledge fundamentally a posteriori, or does a priori intuition provide the modal component of what is known? Though the latter view seems more straightforward, there are also reasons for taking the first option seriously.

Metaphors involve immense explanatory power and positive impact predominantly in the scientific education and popularization. Still the use of metaphors in science might be a double-edged sword. Introduction of the computer metaphor to many scientific fields in the last century resulted in reductionist approaches, oversimplifications and mechanistic explanations in science as well as in humanities. In this short commentary we developed further the computer metaphor by prof. Noble and the illusions this metaphor led to in genetics, linguistics and consequently DNA (...) linguistics. (shrink)

This article describes a qualitative inquiry into the historical reception of Flemish television fiction broadcast by the monopolistic Flemish broadcaster BRT between 1953 and 1989. This is a relatively homogeneous period, both in terms of broadcasting policies and fiction output. What do viewers remember of this period? Can patterns be discerned in these memories, and if so, why? To answer these questions, this research uses semi-structured interviews with older viewers. First, the article discusses the particular problems of this method, mostly (...) ‘faulty’ memory and nostalgic reinterpretation. Then, the findings are presented, reflecting on processes of memory formation. One clear finding concerns the selective and homogeneous nature of memories; the same few serials are remembered in similar ways by most, leading to clichéd memories of the past. (shrink)

The article provides a reply to critical remarks made during the discussion about creativity and scientific knowledge. The authors propose to consider their concept of creativity not as antagonistic or incommensurable with the alternative, but rather co-existing through the complementarity principle. Responding to a comment about the socio-cultural conditionality of a particular cognitive situation, the authors question whether globalization seriously influence this matter in science. They support the statement about the importance of the interaction between science and art, science and (...) philosophy as an opportunity to consider scientific problems from the outside, in an unusual way. Regarding the comment about serendipity, the authors note that in certain cases we need exactly epistemological randomization, since we cannot consciously induce serendipity. In conclusion, thanks are expressed to all participants in the discussion. (shrink)

Christianity has understood the environment as a gift to nurture and steward, a book of divine revelation disclosing the divine mind, a wild garden in need of cultivation and betterment, and as a resource for the creation of a new Eden. This Cambridge Companion details how Christianity, one of the world's most important religions, has shaped one of the existential issues of our age, the environment. Engaging with contemporary issues, including gender, traditional knowledge, and enchantment, it brings together the work (...) of international scholars on the subject of Christianity and the Environment from a diversity of fields. Together, their work offers a comprehensive guide to the complex relationship between Christianity and the environment that moves beyond disciplinary boundaries. To do this, the volume explains the key concepts concerning Christianity and the environment, outlines the historical development of this relationship from antiquity to the present, and explores important contemporary issues. (shrink)

The author considers the thesis about the opposition between the universal (philosophy of science) and particular (history of science), and about the retreat of epistemology in their juxtaposition to the transformations in contemporary philosophy during last decades and its links to science studies. He claims that in order to define historical epistemology project a reason to support this project is to be found.