In their article “The Rise of Citizen Science in Health and Biomedical Research,” Wiggins and Wilbanks (2019) present a new typology for understanding the complex landscape of health and biomedical...

Background Citizen science is increasingly prevalent in the biomedical sciences, including the field of human genomics. Genomic citizen science initiatives present new opportunities to engage individuals in scientific discovery, but they also are provoking new questions regarding who owns the outputs of the research, including intangible ideas and discoveries and tangible writings, tools, technologies, and products. The legal and ethical claims of participants to research outputs become stronger—and also more likely to conflict with those of institution-based researchers and other stakeholders—as (...) participants become more involved, quantitatively and qualitatively, in the research process. It is not yet known, however, how genomic citizen science initiatives are managing the interests of their participants in accessing and controlling research outputs in practice. To help fill this gap, we conducted an in-depth review of relevant policies and practices of U.S.-based genomic citizen science initiatives. Methods We queried the peer-reviewed literature and grey literature to identify 22 genomic citizen science initiatives that satisfied six inclusion criteria. A data collection form was used to capture initiative features, policies, and practices relevant to participants’ access to and control over research outputs. Results This analysis revealed that the genomic citizen science landscape is diverse and includes many initiatives that do not have institutional affiliations. Two trends that are in apparent tension were identified: commercialization and operationalization of a philosophy of openness. While most initiatives supported participants’ access to research outputs, including datasets and published findings, none supported participants’ control over results via intellectual property, licensing, or commercialization rights. However, several initiatives disclaimed their own rights to profit from outputs. Conclusions There are opportunities for citizen science initiatives to incorporate more features that support participants’ access to and control over research outputs, consistent with their specific objectives, operations, and technical capabilities. (shrink)

It is often noted that institutional objects and artifacts depend on human beliefs and intentions and so fail to meet the realist paradigm of mind-independent objects. In this paper I draw out exactly in what ways the thesis of mind-independence fails, and show that it has some surprising consequences. For the specific forms of mind-dependence involved entail that we have certain forms of epistemic privilege with regard to our own institutional and artifactual kinds, protecting us from certain possibilities of ignorance (...) and error; they also demonstrate that not all cases of reference to these kinds can proceed along a causal model. As a result, realist views in ontology, epistemology, and semantics that were developed with natural scientific kinds in mind cannot fully apply to the everyday world. In closing I consider some wider consequences of these results for social science and philosophy. (shrink)

The perspectives of genomic citizen scientists on ownership of research outputs are not well understood, yet they are useful for identifying alignment of participant expectations and project practices and can help guide efforts to develop innovative tools and strategies for managing ownership claims. Here, we report findings from 52 interviews conducted in 2018 and 2019 to understand genomic citizen science stakeholders’ conceptualizations of, experiences with, and preferences for ownership of research outputs. Interviewees identified four approaches for recognizing genomic citizen scientists’ (...) ownership and related credit interests in research outputs: shared governance via commons models; fractional ownership of benefits; full and creative attribution; and offensive and defensive patenting. Interviewees also agreed that the model selected by any project should at least maximize access to research outputs and, as appropriate and to the extent possible, broadly distribute rights of control and entitlements to research benefits. (shrink)

Modality presents notorious philosophical problems, including the epistemic problem of how we could come to know modal facts and metaphysical problems about how to place modal facts in the natural world. These problems arise from thinking of modal claims as attempts to describe modal features of this world that explain what makes them true. Here I propose a different view of modal discourse in which talk about what is “metaphysically necessary” does not aim to describe modal features of the world, (...) but, rather, provides a particularly useful way of expressing constitutive semantic and conceptual rules in the object language. The result is a “modal normativist” view that enables us to avoid the epistemic problems of modality and mitigate the metaphysical worries, while also leaving open the possibility of a unified account of the function of modal language. Finally, I address a serious challenge: we have the norms we do in order to track the modal facts of the world, so that the order of explanation must go in the opposite direction. I close by showing how the normativist may answer that challenge. (shrink)

This challenging study places fiction squarely at the centre of the discussion of metaphysics. Philosophers have traditionally treated fiction as involving a set of narrow problems in logic or the philosophy of language. By contrast Amie Thomasson argues that fiction has far-reaching implications for central problems of metaphysics. The book develops an 'artifactual' theory of fiction, whereby fictional characters are abstract artifacts as ordinary as laws or symphonies or works of literature. By understanding fictional characters we come to understand how (...) other cultural and social objects are established on the basis of the independent physical world and the mental states of human beings. (shrink)

Arguments that ordinary inanimate objects such as tables and chairs, sticks and stones, simply do not exist have become increasingly common and increasingly prominent. Some are based on demands for parsimony or for a non-arbitrary answer to the special composition question; others arise from prohibitions against causal redundancy, ontological vagueness, or co-location; and others still come from worries that a common sense ontology would be a rival to a scientific one. Until now, little has been done to address these arguments (...) in a unified and systematic way. Ordinary Objects is designed to fill this gap, demonstrating that the mistakes behind all of these superficially diverse eliminativist arguments may be traced to a common source. It aims to develop an ontology of ordinary objects subject to no such problems, providing perhaps the first sustained defense of a common sense ontology in two generations. The work done along the way addresses a number of major issues in philosophy of language and metaphysics, contributing to debates about analyticity, identity conditions, co-location and the grounding problem, vagueness, overdetermination, parsimony, and ontological commitment. In the end, the most important result of addressing these eliminativist arguments is not merely avoiding their conclusions; examining their failings also gives us reason to suspect that many apparent disputes in ontology are pseudo-debates. For it brings into question widely-held assumptions about which uses of metaphysical principles are appropriate, which metaphysical demands are answerable, and how we should go about addressing such fundamental questions as "What exists?". As a result, the work of Ordinary Objects promises to provide not only the route to a reflective understanding of our unreflective common-sense view, but also a better understanding of the proper methods and limits of metaphysics. (shrink)

Philosophical theories often hinge on claims about what is necessary or possible. But what are possibilities and necessities, and how could we come to know about them? This book aims to help demystify the methodology of philosophy, by treating such claims not as attempted descriptions of strange facts or distant 'possible worlds', but rather as ways of expressing rules or norms.

L’article publié ici se propose d’emprunter une voie qui n’avait pas été empruntée dans les explorations précédentes de l’auteur. En effet, on verra qu’il s’agit ici de surmonter les difficultés auxquelles sont confrontées les théories réalistes de la fiction et en particulier la théorie artefactuelle dont Amie Thomasson est l’auteur. La question principale s’édicte en ces termes : s’il y a des personnages de fiction, comment se fait-il qu’il nous soit naturel de dire que tel ou tel personnage n’existe pas (...) ? Comment rendre compte des affirmations de non-existence des personnages de fiction, en particulier lorsqu’on est un réaliste de la fiction ? L’auteur confronte trois manières de traiter ces affirmations : l’approche par la quantification restreinte et l’approche linguistique et enfin l’approche des conditions d’application, point de vue auquel l’auteur se rallie. La première approche consiste à faire des restrictions spatiales ou catégorielles afin de cerner le champ de la référence. La seconde approche, qui est celle que les théoriciens de la référence directe emploient majoritairement, consiste à passer par le métalangage, c’est-à-dire de passer à un niveau sémantique supérieur. La dernière approche, celle par les conditions d’application, est construite sur les vertus des deux premières approches. Enfin, l’auteur élargira l’apport de cette dernière approche aux débats métaphysiques. (shrink)

The COVID-19 pandemic has raised a host of ethical challenges, but key among these has been the possibility that health care systems might need to ration scarce critical care resources. Rationing p...

Amie L. Thomasson; The Ontology of Art and Knowledge in Aesthetics: Thomasson The Ontology of Art and Knowledge in Aesthetics, The Journal of Aesthetics and Art.

Inequitable access to health care, social inequities, and racist and discriminatory care has resulted in the trend toward poorer health outcomes for Indigenous infants and their families when compared to non‐Indigenous families in Canada. How Indigenous mothers experience care during an admission of their infant to the Neonatal Intensive Care Unit has implications for future health‐seeking behaviors which may influence infant health outcomes. Nurses are well positioned to promote positive health care interactions and improve health outcomes by effectively meeting the (...) needs of Indigenous families. This qualitative study was guided by interpretive description and the Two‐Eyed Seeing framework and aimed to understand how Indigenous mothers experience accessing and using the health care system for their infants. Data were collected by way of interviews and a discussion group with self‐identifying Indigenous mothers of infants less than two years of age living in Hamilton, Ontario, Canada. Data underwent thematic analysis, identifying nursing strategies to support positive health care interactions and promote the health and wellness of Indigenous infants and their families. Building relationships, providing holistic care, and taking a trauma‐informed approach to the involvement of child protection services are three key strategies that nurses can use to positively impact health care experiences for Indigenous families. (shrink)

Higher-order theories and neo-Brentanian theories of consciousness both consider conscious states to be states of which we have some sort of.

Two major questions have dominated work on the metaphysics of social groups: first, Are there any? And second, What are they? I will begin by arguing that the answer to the ontological question is an easy and obvious ‘yes’. We do better to turn our efforts elsewhere, addressing the question: “What are social groups?” One might worry, however, about this question on grounds that the general term ‘social group’ seems like a term of art—not a well-used concept we can analyze, (...) or can presuppose corresponds to a real kind we can investigate. But while the general notion of ‘social group’ may be a term of art, our terms for clubs and courts, races and genders, are not. It is worth stepping back to ask what function these social group concepts serve. I will argue that individual social group concepts function to give normative structure to our lives together. Paying attention to the role of norms in social groups, I will argue, can enable us to provide a unified understanding of the importance of core social groups, while still respecting the great differences among social groups of different kinds. (shrink)

Talk of the functions of language or concepts plays a central role in developing an appealing pragmatic approach to conceptual engineering. But some have expressed skepticism that we can make any good sense of the idea of function as applied to concepts or language, or argued that the most we can say is that the function of ‘F’ is to refer to the Fs. In this paper, however, I argue that identifying linguistic functions is not hopeless, and that we can (...) make progress by working at the level of system functions, and drawing on work in systemic functional linguistics. For that enables us to develop a better framework for thinking about the functions that language serves, and the ways its subsystems contribute to those functions. This approach to understanding linguistic functions enables us to develop a pragmatic approach to conceptual engineering that provides standards for conceptual engineering without metaphysical mysteries. It also enables us to make progress in figuring out what functions certain philosophically interesting parts of language serve, and how they are introduced into language, in ways that may disentangle us from a range of old philosophical problems. (shrink)

This article presents the ancient Mesopotamian Mīs Pî ceremony as a case study in the relationship between ritual and the natural world using Roy Rappaport’s framework of Ecological Anthropology as a guide. Rappaport’s premise is that human populations do not operate independently but are instead, “ecological populations in an ecosystem that also includes the other living organisms and the nonliving substances found within the boundaries of [their] territory.” In Rappaport’s framework, rituals involving the use of animal, plant, and other organic (...) materials link human communities to the ecosystems in which they dwell and to that which they seek to ritualize. Applying this mode of analysis to the Mīs Pî ritual yields the thesis that, from the perspective of the Mīs Pî, nature is integral to the ritual maintenance and well-being of the divine and human realms, and, in effect, the well-being of the cosmos. (shrink)

The critics in this volume raise several important challenges to the modal normativist position developed in Norms and Necessity, including whether the relation I claim holds between semantic rules and necessity claims generates spurious claims of metaphysical necessity, whether the view is circular (implicitly relying on a more 'robust' form of modal realism), and whether it conflicts with truth-conditional semantics. They also raise probing questions about how it compares to other views of modality, including a Lewisian view and an essentialist (...) view. In these replies, I respond to these challenges in ways that precisify the relevant understanding of ‘semantic rules' and the forms they can take, that make clearer the direction of explanation in modal normativism in ways that show the view doesn't rely on a more ‘robust’ form of modal realism, and that give reason for thinking that there is actually no conflict between modal normativism and truth-conditional semantics. I also aim to give a fuller assessment of how it compares to other approaches to modality, including an essentialist approach. (shrink)

Philosophy Compass, Volume 1. Oxford: Blackwell, 2006.

It is argued that the work of Husserl offers a model for self-knowledge that avoids the disadvantages of standard introspectionist accounts and of a Sellarsian view of the relation between our perceptual judgements and derived judgements about appearances. Self-knowledge is based on externally directed knowledge of the world that is then subjected to a cognitive transformation analogous to the move from a statement to the activity of stating. Appearance talk is (contra Sellars) not an epistemically non-committal form of speech, but (...) talk to which we are fully committed. However, it is a commitment to a certain kind of claim about our experiences, viewed as cognitive phenomena, after a process of transformation. Such reductive and hypostatizing transformations can exhibit the intentional structure of consciousness. Phenomenology thus gives a form of knowledge about our mental states that is first personal but not introspective knowledge in any philosophically problematic sense. The account offered is also, in key respects, dissimilar to Sellars's outer directed view of the origin of self-knowledge. (shrink)

Microscale techniques have been applied to biological assays for nearly two decades, but haven't been widely integrated as common tools in biological laboratories. The significant differences between several physical phenomena at the microscale versus the macroscale have been exploited to provide a variety of new types of assays (such as gradient production or spatial cell patterning). However, the use of these devices by biologists seems to be limited by issues regarding biological validation, ease of use, and the limited available readouts (...) for assays done using microtechnology. Critical validation work has been done recently that highlights the current challenges for microfluidic methods and suggest ways in which future devices might be improved to better integrate with biological assays. With more validation and improved designs, microscale techniques hold immense promise as a platform to study aspects of cell biology that are not possible using current macroscale techniques. BioEssays 30:811–821, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

Alice considered [the idea of un-birthday presents] a little. “I llke birthday presents best,” she said at last.“You don’t know what you’re talking about!” cried Humpty Dumpty. … “[There are three hundred and sixty-four days when you might get un-birthday presents… And only one for birthday presents, you know. There’s a ‘glory’ for you!”“I don’t know what you mean by ‘glory,’” Alice said.Humpty Dumpty smiled contemptuously. “Of course you don’t—till I tell you. I meant ‘there’s a nice knock-down argument for (...) you!’”“But ‘glory’ doesn’t mean ‘a nice knock-down argument,’” Alice objected.“When I use a word,” Humpty Dumpty said in a rather scornful tone, “it means just what I choose it to mean—neither more nor less.”. (shrink)

[ES] Los trabajos recientes de Stephen Schiffer en el desarrollo de una explicación pleonástica de proposiciones producen resultados importantes que cambian el significado tanto de la ontología de primer orden como de la meta-ontología. El objetivo del presente trabajo es dejar en claro cuáles son estas consecuencias y por qué son tan importantes. Según mi punto de vista, la mayor amenaza para los partidarios de la metafísica proviene de un punto de vista que yo he llamado en otro trabajo el (...) acercamiento «fácil» a la ontología: los argumentos de Schiffer a favor de proposiciones «pleonásticas», propiedades, estados, eventos y personajes ficticios; los argumentos neo-fregeanos a favor de la existencia de números; y mis propios argumentos a favor de objetos sociales, culturales, y personajes ficticios, y objetos ordinarios como mesas y sillas. El trabajo expande estas tres diferentes formas de ontología fácil, mostrando sus interrelaciones y argumenta que estos acercamientos nos dan un realismo ciento por ciento directo, sobre las entidades en cuestión. A un nivel meta-ontológico, sin embargo, el trabajo sugiere que el debate ontológico serio es confundido porque sus preguntas ontológicas tienen respuestas tan directas. Este acercamiento podría ser la amenaza más importante para la metafísica seria, pero también es extremadamente prometedor como una manera de disolver misterios y clarificar la epistemología de la metafísica. [EN] Stephen Schiffer’s recent work in developing a pleonastic account of propositions leads to major, game-changing results in both first-order ontology and meta-ontology. This paper aims to clarify what these consequences are and why they are so important. In my view, the biggest threat to the metaphysical party comes from a view I have elsewhere called the «easy» approach to ontology: Schiffer’s arguments for «pleonastic» propositions, properties, fictional characters, states and events; the neo-Fregean’s arguments for the existence of numbers; and my own arguments for fictional characters, social and cultural objects, and ordinary objects such as tables and chairs. The paper draws out these three different forms of easy ontology, showing their interrelations, and argues that these approaches really give us a straightforward, out and out realism about the entities in question. On the meta-ontological level however, it suggests that serious ontological debate in metaphysics is confused because its ontological questions have so straightforward answers. This approach may be the most important threat to serious metaphysics but it is also extremely promising as a way of dissolving mysteries and clarifying the epistemology of metaphysics. (shrink)

In _The Significance of Consciousness_ , Charles Siewert proposes a novel understanding of consciousness by arguing against higher-order views of consciousness and rejecting the traditional taxonomy of the mental into qualitative and intentional aspects. I discuss two puzzles that arise from these changes: first, how to account for first-person knowledge of our conscious states while denying that these are typically accompanied by higher-order states directed towards them; second, how to understand his claim that phenomenal features are intentional features without either (...) risking consciousness neglect or retreating to a more traditional understanding of the relation between qualitative and intentional character. (shrink)

Increasingly, genomic analysis is being utilized to diagnose children with developmental delay or dysmorphic facial features suggestive of a congenital disorder. Genetic testing has rapidly evolved, and the genome-wide tests that we use today are significantly different from the more targeted single-gene tests of the last decade. Chromosomal microarray analysis is now a first line test for children with multiple birth defects, children with intellectual impairment, and children with an unusual constellation of symptoms that do not fit with a known (...) disease. There are three types of CMA that are currently clinically available. CMA by oligonucleotide array-based comparative genomic hybridization compares the hybridization signal from the patient's DNA to that of a reference DNA sample for each oligonucleotide on the array. Depending on the specific array, this can range from tens of thousands to hundreds of thousands of oligonucleotides. (shrink)

As therapeutic advances in the treatment of AIDS began to emerge in the late 1980s and public health began to have more to offer than just the threat, or the perceived threat, of quarantine or partner notification, fissures began to appear in the alliance against named HIV reporting that had emerged a few years earlier. In 1989, New York City’s Health Commissioner stated that the prospects of early clinical intervention warranted “a shift toward a disease-control approach to HIV infection along (...) the lines of classic tuberculosis practices,” including the “reporting of seropositives.”Although his proposal met with fierce and effective resistance, it is now clear that his call represented part of a national trend. The CDC continued to press for cases of HIV to he reported by name to health departments, an effort that assumed the dimensions of a campaign. It was supported by a growing number of public health officials. (shrink)

The existence of a social world raises both the metaphysical puzzle: how can there be a “reality” of facts and objects that are genuinely created by human intentionality? and the epistemological puzzle: how can such a product of human intentionality include objective facts available for investigation and discovery by the social sciences? I argue that Searle’s story about the creation of social facts in The Construction of Social Reality is too narrow to fully solve either side of the puzzle. By (...) acknowledging different forms of rules for constructing social reality paralleling rules for creating ‘make-believe’ truths, we can build a more comprehensive social ontology and allow for a more appropriate range of discovery for the social sciences. Nonetheless, I argue that despite the parallels between methods for constructing make-believe and social facts, it would be mistaken to treat talk about social reality as involving a mere pretense to refer. (shrink)

In his Gospel, John reveals this key leadership principle: effective leaders harness the power of narrative to illuminate the metanarrative and connect people to it. John uses narrative techniques to make invisible spiritual realities visible and thus succeeds in connecting people to the metanarrative. John forges a link between people and the metanarrative by showing individuals how their own stories fit into the biblical metanarrative, fulfilling his purpose: ‘These are written that you may believe…’. The church is transmitted through the (...) ages by leaders who write. Because the metanarrative is a story and story is accessible to all audiences, the biblical metanarrative is not dependent on culture, time, or context; it transcends the ages, enabling John to lead and write from the present as well as for the future. Thus, John illuminates the metanarrative not only for the infant church but for all Christians to come. Christian leaders today also need to communicate so their people can see their place in the metanarrative of Scripture. (shrink)

In “The Standing to Blame: A Critique” (2013), Macalester Bell challenges theories that claim that ‘standing’ plays a central role in blaming practices. These standard accounts posit that it is not enough for the target of blame to be blameworthy; the blamer also must have the proper standing to blame the wrongdoer. Bell identifies and criticizes four different standing conditions, (1) the Business Condition, (2) the Contemporary Condition, (3) the Nonhypocricy Condition, and (4) the Noncomplicity Condition. According to standard accounts, (...) these conditions must be met in order for a would-be blamer to properly blame a wrongdoer. In this paper, I defend the Business Condition against Bell’s critique. My argument, then, is that some version of the standard account survives and ‘standing’ should be part of our theory of properly-wielded blame. I conclude by raising two additional concerns regarding the agency of blamers and the possibility that, without proper standing, a blamer could make things worse. (shrink)

The challenge of handling fictional discourse is to find the best way to resolve the apparent inconsistencies in our ways of speaking about fiction. A promising approach is to take at least some such discourse to involve pretense, but does all fictional discourse involve pretense? I will argue that a better, less revisionary, solution is to take internal and fictionalizing discourse to involve pretense, while allowing that in external critical discourse, fictional names are used seriously to refer to fictional characters. (...) I then address two objections to such realist theories of fiction: One, that they can’t adequately account for the truth of singular nonexistence claims involving fictional names, and two, that accepting that there are fictional characters to which we refer is implausible or ontologically profligate. (shrink)

While fights about ontology rage on in the ring, there’s long been a suspicion whispered in certain corners of the stadium that some of the fights aren’t real. Granted the disputants all think they are really disagreeing—it’s not the sincerity of the serious ontologists that’s in question, but rather their judgment that they are engaged in a real debate about genuine issues of substance.

My purpose in this dissertation is to investigate the workings of the imagination. As I argue in Chapter One, such an investigation reveals that we cannot adequately account for the phenomenon of imagining without invoking mental imagery. I thus develop and defend an imagery-based account of the imagination, which I call the imagery model. ;Despite its intuitive appeal and a long philosophical history, the imagery model has nonetheless fallen into disfavor in contemporary discussions of the imagination. This is due, at (...) least in part, to a strong presumption against mental images that has developed in this century. Overcoming this presumption is the primary task of Chapter Two. In Chapter Three, I address a second motivation for the rejection of the imagery model, namely, that there seem to be some mental exercises which are clearly exercises of the imagination but yet which do not consist of imagery. By separating the imagery model from several controversial theses with which it has been associated, I show how the imagery model can protect itself from the threat of these counterexamples. ;Once these obstacles to the acceptance of the imagery model have been removed, the need remains to provide an explanation of the role that the image plays in imagining. As I suggest, although the image is not what is imagined, it is in virtue of the image that anything is imagined at all. More specifically, the image serves to capture the subject of the imagining. My discussion of this claim in Chapter Four is heavily influenced by recent work in the philosophy of language; in particular, I rely on many of the insights of the causal theory of reference developed by Saul Kripke and Keith Donnellan. ;Ultimately, having developed a picture of the workings of the imagination, I take up what I call the question of imaginability, namely, "What can we imagine?" The imagery model yields the obvious result that the imaginable is limited to the imageable. I explore the consequences of this result and, in particular, the consequences it has for the use of the imagination as an epistemological guide to modality. (shrink)

Fairchild, Center for the History and Ethics of Public Health in the Department of Sociomedical Sciences at Columbia University's Mailman School of Public Health Abstract Surveillance is a cornerstone of public health. It permits us to recognize disease outbreaks, to track the incidence and prevalence of threats to public health, and to monitor the effectiveness of our interventions. But surveillance also challenges our understandings of the significance and role of privacy in a liberal democracy. In this paper we trace the (...) century-long history of public health surveillance in the United States situating that history in the context of the broad social, political, and ideological forces that have shaped our conceptions of privacy. Although we focus here on the United States, the debates over privacy that unfolded in the 1960s were repeated in many European nations. The themes we explore here, then, provide a framework for examining the relationship between privacy and public health in other contexts. CiteULike Connotea Del.icio.us What's this? (shrink)