When deciding what disorders to screen newborns for, we should be guided by evidence of real effectiveness, take opportunity cost into account, distribute costs and benefits fairly, and respect human rights. Current newborn screening policy does not meet these requirements.

Bishop is a professor of nursing; Scudder is a professor of philosophy.

From a post-structuralist position, it is problematic and seemingly impossible to refer to God as the Trinity. This article describes possibilities for thinking about the Trinity (religion and God) within a post-structuralist context. As an example of such thinking, the 2015 culture-critique film, The Brand New Testament, will be analysed. It is a creative retelling of the Christian story and of the Trinity in a secular and post-metaphysical vein. This ‘Brand New Testament’ reveals God as ‘one’ – as the encompassing (...) love, hope and life which we may experience in this life. The life-giving characteristics of this ‘god’ are surprisingly close to the biblical understanding of the Trinity. In the ‘Brand New Testament’, however, the Trinity is portrayed radically differently than in the Christian tradition. The personae of father, son and spirit are deconstructed in the film, in that a daughter and a mother also form part of the godhead. This deconstruction of the Trinity, which should not be confused with blasphemy, opens up a possible post-structuralist imagining of God. It playfully reveals a powerless god who shares some fundamental characteristics with the Trinity – such as love, joy and life. It allows for the ‘oneness of god’ to include more, and less, than the ‘Holy Trinity’. (shrink)

In our multicultural, globalised and increasingly postmodern world, people live within competing and contradicting philosophies, and the question of ethics becomes extremely pertinent. It is within this context that this article sheds light on ethics by comparing ubuntu, as part of the African philosophical tradition, and transimmanence, as part of the Western deconstructionist philosophical tradition. As divergent as these traditions may be, ethics are a key feature in both and a crucial point of overlap. Notions of identity, personhood, the community (...) and sense (meaning), for example, play a pivotal role in ubuntu and transimmanence. A reading of these two contrasting philosophical traditions (ubuntu and transimmanence), each through the lens of the other, helps one to develop a better understanding of each of these traditions with regard to their respective ethics and eventually to develop a better understanding of ethics per se. (shrink)

Advocacy has been positioned as an ideal within the practice of nursing, with national guidelines and professional standards obliging nurses to respect patients' autonomous choices and to act as their advocates. However, the meaning of advocacy and autonomy is not well defined or understood, leading to uncertainty regarding what is required, expected and feasible for nurses in clinical practice. In this article, a feminist ethics perspective is used to examine how moral responsibilities are enacted in the perinatal nurse—patient relationship and (...) to explore the interaction between the various threads that influence, and are in turn affected by, this relationship. This perspective allows for consideration of contextual and relational factors that impact on the way perinatal nursing care is given and received, and provides a framework for exploring the ways in which patient autonomy, advocacy and choice are experienced by childbearing women and their nurses during labour and birth. (shrink)

It is postulated from different philosophical traditions, and explicitly in recent literature, that there is no further need for doing philosophy of religion – it has become an impossible task. I argue, however, that there remains a philosophical space for this practice and that this space determines greatly how philosophy of religion can be done. The starting point of my argument is the current discussion in the SAJP between De Wet and Giddy and the significance of my article is that (...) it puts this debate within the broader international philosophical context by engaging the work of Trakakis and Desmond to resolve some of the apparently intractable issues raised. Trakakis discusses the divide between the analytic and continental philosophical traditions in which De Wet and Giddy’s work is further contextualized and clarified. Desmond’s work is seminal in its search for a metaxology wherein he advocates a new ‘in between’ position for doing philosophy of religion. I take this view of Desmond further by applying it to the current debate in South Africa and also using it to indicate some possibilities of speaking about the impossible. (shrink)

This article brings into perspective the need to decolonise the concept of the Trinity (as the specific doctrine and Christian name of God) as a crucial step in decolonising the religious education curriculum. It discusses the concept of decolonisation and its applicability to religious education, specifically Christianity, within higher education (e.g. in Teacher Education Programmes) in the South African context. God as the Trinity has throughout the history of Atlantic slavery and colonialism been employed to legitimise colonial rule and it, (...) therefore, needs to be decolonised. To decolonise the concept of the Trinity is, however, highly problematic, as the historic relation between Christianity and African traditional religions (ATRs) indicates. Decolonising the concept of the Trinity can quickly develop into a tension between a position of either continuity or discontinuity (of ATR with Christianity). Contribution: This article argues for an alternative approach for the decolonisation of the concept of the Trinity, namely to allow for the deconstruction of the concept of the Trinity, and by implication of other concepts – like decolonisation and religion – as well. This approach is proposed to develop more openness and playfulness with regard to religious beliefs in general. I argue that this may provide a hopeful, open and just vision of life which should be part of the decolonised religious education curriculum. (shrink)

Wynn's model for the evolution of spatial cognition is well supported by fossil evidence from brain endocasts, and from neurological studies of the cerebellum and the posterior parietal region of the cerebral cortex. Wynn's intriguing hypothesis that the spatial skill reflected in artifacts is an index of navigational ability, could be further explored by an analysis of lithic transport patterns.

Although international research is increasing in volume and importance, there remains a dearth of knowledge on similarities and differences in “national human research ethics”, that is, national ethical guidelines, Institutional Review Boards, and research stakeholder’ ethical attitudes and behaviors. We begin to address this situation by reporting upon our experiences in conducting a multinational study into the mental health of children who had a parent/carer in prison. The study was conducted in 4 countries: Germany, Great Britain, Romania, and Sweden. Data (...) on NHREs were gathered via a questionnaire survey, two ethics-related seminars, and ongoing contact between members of the research consortium. There was correspondence but even more so divergence between countries in the availability of NEGs and IRBs and in researcher’ EABs. Differences in NHREs have implications particularly in terms of harmonization but also for ethical philosophy and practice and for research integrity. (shrink)

AimWhite matter changes in individuals at ultra-high risk for psychosis may be involved in the transition to psychosis. Sleep-wake disturbances commonly precede the first psychotic episode and predict development of psychosis. We examined associations between white matter microstructure and sleep-wake disturbances in UHR individuals compared to healthy controls, as well as explored the confounding effect of medication, substance use, and level of psychopathology.MethodsSixty-four UHR individuals and 35 HC underwent clinical interviews and diffusion weighted imaging. Group differences on global and callosal (...) mean fractional anisotropy was tested using general linear modeling. Sleep-wake disturbances were evaluated using the subjective measures disturbed sleep index and disturbed awakening index from the Karolinska Sleep Questionnaire, supported by objective sleep measures from one-night actigraphy. The primary analyses comprised partial correlation analyses between global FA/callosal FA and sleep-wake measures. Secondary analyses investigated multivariate patterns of covariance between measures of sleep-wake disturbances and FA in 48 white matter regions of interest using partial least square correlations.ResultsUltra-high risk for psychosis individuals displayed lower global FA and lower callosal FA compared to HC. Subjective sleep-wake disturbances were significantly higher among the UHR individuals. Lower callosal FA was correlated with increased wake after sleep onset and increased sleep fragmentation index in UHR individuals. Multivariate analyses identified a pattern of covariance in regional FA which were associated with DSI and AWI in UHR individuals, but not in HC. Substance use, sleep medication and antipsychotic medication did not significantly confound these associations. The association with objective sleep-wake measures was sustained when controlling for level of depressive and UHR symptoms, but symptom level confounded the covariation between FA and subjective sleep-wake measures in the multivariate analyses.ConclusionCompromised callosal microstructure in UHR individuals was related to objectively observed disruptions in sleep-wake functioning. Lower FA in ventrally located regions was associated with subjectively measured sleep-wake disturbances and was partly explained by psychopathology. These findings call for further investigation of sleep disturbances as a potential treatment target. (shrink)