34 found
Order:
Disambiguations
Anneke Lucassen [24]Anneke M. Lucassen [11]
  1.  20
    Focusing attention on physicians’ climate-related duties may risk missing the bigger picture: towards a systems approach to health and climate.Gabby Samuel, Sarah Briggs, Kate Lyle & Anneke M. Lucassen - 2024 - Journal of Medical Ethics 50 (6):380-381.
    Gils-Schmidt and Salloch recognise that human and climate health are inextricably linked, and that mitigating healthcare-associated climate harms is essential for protecting human health.1 They argue that physicians have a duty to consider how their own practices contribute to climate change, including during their interactions with patients. Acknowledging the potential for conflicts between this duty and the provision of individual patient care, they propose the application of Korsgaard’s neo-Kantian account of practical identities to help navigate such scenarios. In this commentary, (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  2.  8
    Ethical preparedness in genomic medicine: how NHS clinical scientists navigate ethical issues.Kate Sahan, Kate Lyle, Helena Carley, Nina Hallowell, Michael J. Parker & Anneke M. Lucassen - forthcoming - Journal of Medical Ethics.
    Much has been published about the ethical issues encountered by clinicians in genetics/genomics, but those experienced by clinical laboratory scientists are less well described. Clinical laboratory scientists now frequently face navigating ethical problems in their work, but how they should be best supported to do this is underexplored. This lack of attention is also reflected in the ethics tools available to clinical laboratory scientists such as guidance and deliberative ethics forums, developed primarily to manage issues arising within the clinic.We explore (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  3.  13
    Beyond regulatory approaches to ethics: making space for ethical preparedness in healthcare research.Kate Lyle, Susie Weller, Gabby Samuel & Anneke M. Lucassen - 2023 - Journal of Medical Ethics 49 (5):352-356.
    Centralised, compliance-focused approaches to research ethics have been normalised in practice. In this paper, we argue that the dominance of such systems has been driven by neoliberal approaches to governance, where the focus on controlling and individualising risk has led to an overemphasis of decontextualised ethical principles and the conflation of ethical requirements with the documentation of ‘informed consent’. Using a UK-based case study, involving a point-of-care-genetic test as an illustration, we argue that rather than ensuring ethical practice such compliance-focused (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   5 citations  
  4.  16
    ‘Is this knowledge mine and nobody else's? I don't feel that.’ Patient views about consent, confidentiality and information-sharing in genetic medicine: Table 1.Sandi Dheensa, Angela Fenwick & Anneke Lucassen - 2016 - Journal of Medical Ethics 42 (3):174-179.
    Direct download (9 more)  
     
    Export citation  
     
    Bookmark   12 citations  
  5.  4
    Ethical Considerations in Research with Genomic Data.Rachel Horton & Anneke Lucassen - 2022 - The New Bioethics 29 (1):37-51.
    Our ability to generate genomic data is currently well ahead of our ability to understand what they mean, raising challenges about how best to engage with them. This article considers ethical aspects of work with such data, focussing on research contexts that are intertwined with clinical care. We discuss the identifying nature of genomic data, the medical information intrinsic within them, and their linking of people within a biological family. We go on to consider what this means for consent, the (...)
    No categories
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  6.  10
    Familial genetic risks: how can we better navigate patient confidentiality and appropriate risk disclosure to relatives?Edward S. Dove, Vicky Chico, Michael Fay, Graeme Laurie, Anneke M. Lucassen & Emily Postan - 2019 - Journal of Medical Ethics 45 (8):504-507.
    This article investigates a high-profile and ongoing dilemma for healthcare professionals, namely whether the existence of a duty of care to genetic relatives of a patient is a help or a hindrance in deciding what to do in cases where a patient’s genetic information may have relevance to the health of the patient’s family members. The English case ABC v St George’s Healthcare NHS Trust and others considered if a duty of confidentiality owed to the patient and a putative duty (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   6 citations  
  7.  9
    Is it acceptable to contact an anonymous egg donor to facilitate diagnostic genetic testing for the donor-conceived child?Rachel Horton, Benjamin Bell, Angela Fenwick & Anneke M. Lucassen - 2019 - Journal of Medical Ethics 45 (6):357-360.
    We discuss a case where medically optimal investigations of health problems in a donor-conceived child would require their egg donor to participate in genetic testing. We argue that it would be justified to contact the egg donor to ask whether she would consider this, despite her indicating on a historical consent form that she did not wish to take part in future research and that she did not wish to be informed if she was found to be a carrier of (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   6 citations  
  8.  9
    Ethical preparedness and developments in genomic healthcare.Bobbie Farsides & Anneke M. Lucassen - forthcoming - Journal of Medical Ethics.
    Considerations of the notion of preparedness have come to the fore in the recent pandemic, highlighting a need to be better prepared to deal with sudden, unexpected and unwanted events. However, the concept of preparedness is also important in relation to planned for and desired interventions resulting from healthcare innovations. We describe ethical preparedness as a necessary component for the successful delivery of novel healthcare innovations, and use recent advances in genomic healthcare as an example. We suggest that practitioners and (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   2 citations  
  9.  5
    Using biomarkers in acute medicine to prevent hearing loss: should this require specific consent?Peta Coulson-Smith & Anneke Lucassen - 2020 - Journal of Medical Ethics 46 (8):536-537.
    In this round table response, we discuss some of the problems inherent in insisting on specific consent for an activity that needs to happen rapidly as part of a package of care. The Human Tissue Authority consider that specific consent is mandatory to assess which antibiotics are appropriate on the neonatal unit, but this insistence may actually limit the autonomy which consent aims to promote. While genetic testing to determine which child will react adversely to particular antibiotics has been available (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   4 citations  
  10.  2
    The moral argument for heritable genome editing requires an inappropriately deterministic view of genetics.Rachel Horton & Anneke M. Lucassen - 2019 - Journal of Medical Ethics 45 (8):526-527.
    Gyngell and colleagues consider that the recent Nuffield Council report does not go far enough: heritable genome editing is not just justifiable in a few rare cases; instead, there is a moral imperative to undertake it. We agree that there is a moral argument for this, but in the real world it is mitigated by the fact that it is not usually possible to ensure a better life. We suggest that a moral imperative for HGE can currently only be concluded (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  11.  10
    In Defense of Best Interests: When Parents and Clinicians Disagree.Peta Coulson-Smith, Angela Fenwick & Anneke Lucassen - 2018 - American Journal of Bioethics 18 (8):67-69.
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  12.  18
    The Road to Clinical Fantasy: A UK Perspective.Angela Fenwick, Peta Coulson-Smith & Anneke Lucassen - 2018 - American Journal of Bioethics 18 (1):26-27.
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  13.  10
    Testing children for adult onset conditions: the importance of contextual clinical judgement.Anneke Lucassen & Angela Fenwick - 2012 - Journal of Medical Ethics 38 (9):531-532.
  14.  18
    Genetic Testing of Children: The Need for a Family Perspective.Anneke Lucassen, Guy Widdershoven, Suzanne Metselaar, Angela Fenwick & Michael Parker - 2014 - American Journal of Bioethics 14 (3):26-28.
  15.  13
    Recall of participation in research projects in cancer genetics: some implications for research ethics.Sarah Cooke, Gillian Crawford, Michael Parker, Anneke Lucassen & Nina Hallowell - 2008 - Clinical Ethics 3 (4):180-184.
    The aim of this study is to assess patients' recall of their previous research participation. Recall was established during interviews and compared with entries from clinical notes. Participants were 49 patients who had previously participated in different types of research. Of the 49 patients, 45 (92%) interviewees recalled 69 of 109 (63%) study participations. Level of recall varied according to the type of research, some participants clearly recalled the details of research aims, giving consent and research procedures. Others recalled procedures (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   5 citations  
  16.  8
    Advocating for a Context Specific Approach to Tackle Inequities.Gabrielle Samuel, Faranak Hardcastle & Anneke Lucassen - 2024 - American Journal of Bioethics 24 (3):109-111.
    In her paper, Galasso contends that transitioning precision medicine from its current emphasis on healthcare benefits, to a focus on precision public health, may help address the equity concerns th...
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  17.  16
    Dimensions of responsibility in medical genetics: exploring the complexity of the “duty to recontact”.Shane Doheny, Angus Clarke, Daniele Carrieri, Sandi Dheensa, Naomi Hawkins, Anneke Lucassen, Peter Turnpenny & Susan Kelly - 2018 - New Genetics and Society 37 (3):187-206.
    Discussion of a “duty to recontact” emerged as technological advances left professionals considering getting back in touch with patients they had seen in the past. While there has been much discussion of the duty to recontact as a matter of theory and ethics, there has been rather little empirically based analysis of what this “duty” consists of. Drawing on interviews with 34 professionals working in, or closely with, genetics services, this paper explores what the “duty to recontact” means for healthcare (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  18.  9
    Ethics and research governance: the views of researchers, health-care professionals and other stakeholders.Nina Hallowell, Sarah Cooke, Gill Crawford, Michael Parker & Anneke Lucassen - 2008 - Clinical Ethics 3 (2):85-90.
    The objective of this study is to describe researchers', health-care providers' and other stakeholders' views of ethical review and research governance procedures. The study design involved qualitative semi-structured interviews. Participants included 60 individuals who either undertook research in the subspecialty of cancer genetics (n = 40) or were involved in biomedical research in other capacities (n = 20), e.g. research governance and oversight, patient support groups or research funding. While all interviewees observed that oversight is necessary to protect research participants, (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   3 citations  
  19.  8
    The UK Genethics Club: clinical ethics support for genetic services.Anneke Lucassen & Michael Parker - 2006 - Clinical Ethics 1 (4):219-223.
    The UK Genethics Club was established in November 2001 in order to provide a national forum of ethics support for the profession of clinical genetics in the UK. The forum brings together health professionals, medical ethicists and lawyers and support is provided through detailed discussion of cases and sharing of good practice. Clinical genetics professionals had previously voiced concerns about making extremely difficult ethical decisions, with profound implications, in something of a vacuum. Professionals saw a lack of guidance in the (...)
    Direct download  
     
    Export citation  
     
    Bookmark   3 citations  
  20.  15
    Relative Risk and Relatives' Risks in Genomic Medicine.Angela Fenwick, Shiri Shkedi-Rafid & Anneke Lucassen - 2016 - American Journal of Bioethics 16 (2):25-27.
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  21.  12
    Rescue Obligations and Collective Approaches: Complexities in Genomics.Angela Fenwick, Sandi Dheensa, Gillian Crawford, Shiri Shkedi-Rafid & Anneke Lucassen - 2015 - American Journal of Bioethics 15 (2):23-25.
  22.  4
    I Had Genetic Testing for Alzheimer’s Disease Without My Consent.Anneke Lucassen - 2015 - Narrative Inquiry in Bioethics 5 (3):214-216.
  23.  7
    Discussion of off-target and tentative genomic findings may sometimes be necessary to allow evaluation of their clinical significance.Rachel H. Horton, William L. Macken, Robert D. S. Pitceathly & Anneke M. Lucassen - 2024 - Journal of Medical Ethics 50 (5):295-298.
    We discuss a case where clinical genomic investigation of muscle weakness unexpectedly found a genetic variant that might (or might not) predispose to kidney cancer. We argue that despite its off-target and uncertain nature, this variant should be discussed with the man who had the test, not because it is medical information, but because this discussion would allow the further clinical evaluation that might lead it to becoming so. We argue that while prominent ethical debates around genomics often take ‘results’ (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  24.  8
    Narrative Symposium: Patient and Research Participant experiences with Genetic Testing.Dena Davis, Sarah Foye, Sarah M. Hartz, Carla C. Keirns, Christopher M. Lietz, Anneke Lucassen, Jacqueline Savard, K. A. Strong, Kiri Sunde, Michael J. Young, Anonymous One & Anonymous Two - 2015 - Narrative Inquiry in Bioethics 5 (3):203-228.
    No categories
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark  
  25.  10
    Unpacking the Concept of a Genomic Result.Angela Fenwick, Anneke Lucassen & Rachel Horton - 2019 - American Journal of Bioethics 19 (1):70-71.
    Direct download (4 more)  
     
    Export citation  
     
    Bookmark  
  26.  5
    Old consent and new developments: health professionals should ask and not presume.Rachel Horton, Angela Fenwick & Anneke M. Lucassen - 2020 - Journal of Medical Ethics 46 (6):412-413.
    We thank Lucy Frith for her thought-provoking response1 to our paper, where we argued that it would be ethically acceptable to contact an anonymous egg donor to help facilitate diagnostic genetic testing for a donor-conceived child.2 While we read Frith’s commentary with interest, we still think that the egg donor should be contacted in the case that we describe. Frith raises concerns as to whether contact would constitute ‘ overriding consent ’, thus ’ potentially set a dangerous precedent ’ for (...)
    Direct download (5 more)  
     
    Export citation  
     
    Bookmark  
  27.  3
    Families and genetic testing: the case of Jane and Phyllis.Anneke Lucassen - 2005 - In Richard E. Ashcroft (ed.), Case analysis in clinical ethics. New York: Cambridge University Press. pp. 7--26.
    Direct download  
     
    Export citation  
     
    Bookmark  
  28.  3
    Response to ethical dissections of the case.Anneke Lucassen - 2005 - In Richard E. Ashcroft (ed.), Case analysis in clinical ethics. New York: Cambridge University Press. pp. 213.
    Direct download  
     
    Export citation  
     
    Bookmark  
  29.  10
    Using a biomarker acutely to identify babies at risk of serious adverse effects from antibiotics: where is the ‘Terrible Moral and Medical Dilemma’?Anneke M. Lucassen, John Henry McDermott & William Newman - 2021 - Journal of Medical Ethics 47 (2):117-118.
    We thank Parker and Wright for engaging in this roundtable debate in such a spirited way. The ‘Pharmacogenetic [test] to Avoid Loss of Hearing’ Trial is the first time a genetic point of care test has been applied in the acute neonatal setting; therefore, it is not surprising that questions have been raised which require debate, discussion and clarification. Parker and Wright misattribute several assumptions to the roundtable authors, which we would like to clarify here. Since they raise wider questions (...)
    Direct download (3 more)  
     
    Export citation  
     
    Bookmark  
  30.  5
    Mainstreaming genetics: the potential for miscommunication.Donna McBride & Anneke Lucassen - 2011 - Clinical Ethics 6 (4):159-161.
  31.  8
    Clinical Ethics Committee Case 14: How should we transfer a euthanasia request between general practice and a hospital setting?Bert Molewijk & Anneke Lucassen - 2011 - Clinical Ethics 6 (2):58-63.
  32.  11
    The shifting sands of patient autonomy and public interest considerations in health care.Robert Wheeler, Paul Spargo & Anneke Lucassen - 2011 - Clinical Ethics 6 (4):203-206.
    The past few decades have seen patient autonomy ascend to a prime position in health care. Patient consent is seen as a key component to expression of autonomy. Yet, interventions may also be justified without consent because they are deemed to be in the public interest. We observe some subtle shifts in balance in these justifications in health care and illustrate these with a range of examples. We hope thereby to stimulate a more explicit debate so that health-care professionals can (...)
    Direct download (2 more)  
     
    Export citation  
     
    Bookmark   1 citation  
  33.  13
    Towards a national genomics medicine service: the challenges facing clinical-research hybrid practices and the case of the 100 000 genomes project. [REVIEW]Sandi Dheensa, Gabrielle Samuel, Anneke M. Lucassen & Bobbie Farsides - 2018 - Journal of Medical Ethics 44 (6):397-403.
    Clinical practice and research are governed by distinct rules and regulations and have different approaches to, for example, consent and providing results. However, genomics is an example of where research and clinical practice have become codependent. The 100 000 genomes project is a hybrid venture where a person can obtain a clinical investigation only if he or she agrees to also participate in ongoing research—including research by industry and commercial companies. In this paper, which draws on 20 interviews with professional (...)
    Direct download (8 more)  
     
    Export citation  
     
    Bookmark   6 citations  
  34.  9
    The Troubled Helix: Social and Psychological Implications of the New Human Genetics: Edited by Theresa Marteau and Martin Richards, Cambridge, UK, Cambridge University Press, 1999, 359 pages, pound18.95/US$29.95 (pb). [REVIEW]Anneke Lucassen - 2000 - Journal of Medical Ethics 26 (6):479-1.
    This excellent compilation of essays covers a broad range of genetic topics and is a must for anyone interested in the ethical, social, legal, and historical perspectives of human genetics. This is not a new edition but a paperback version of the 1996 edition. The book begins with a section on “the voices of family members whose lives have been deeply touched by genetic disease”. There are ten very moving accounts of individuals' experiences of a range of different ….
    Direct download (8 more)  
     
    Export citation  
     
    Bookmark