Arsenic and phosphorus are group 15 elements with similar chemical properties. Is it possible that arsenate could replace phosphate in some of the chemicals that are required for life? Phosphate esters are ubiquitous in biomolecules and are essential for life, from the sugar phosphates of intermediary metabolism to ATP to phospholipids to the phosphate backbone of DNA and RNA. Some enzymes that form phosphate esters catalyze the formation of arsenate esters. Arsenate esters hydrolyze very rapidly in aqueous solution, which makes (...) it improbable that phosphorous could be completely replaced with arsenic to support life. Studies of bacterial growth at high arsenic:phosphorus ratios demonstrate that relatively high arsenic concentrations can be tolerated, and that arsenic can become involved in vital functions in the cell, though likely much less efficiently than phosphorus. Recently Wolfe‐Simon et al. 1 reported the isolation of a microorganism that they maintain uses arsenic in place of phosphorus for growth. Here, we examine and evaluate their data and conclusions. (shrink)

I have attempted to present a meta-theory for ethical theories which naturally fits in with a general pragmatic philosophical orientation. There are standard problems for such philosophical views to which I have tried to offer solutions. In addition to the meta-theory one would like to see an actual ethical theory which would exemplify that meta-theory, but that is a topic more appropriate for another time.

Bernard Rosen argues Mill's critics and supporters address one level or another, often without noting which one it is. The positions of important ethical theorists who have been influenced by, or who criticize Mill are presented."--BOOK JACKET.

A summary is out of place because of the outlinish nature of the presentation. I have presented a taxonomy or general theory of ethics. The view is acceptable or not depending on how well it competes with rival theories. One thing that hinders such a comparison is the absence of sufficiently clearly articulated rivals. Perhaps this paper will stimulate the production of some rival views.

The protection of employee rights in the workplace is one of the fundamental ethical questions facing organizations today. Organizations differ in the extent to which they protect the rights of both employees and themselves as employers, yet little research has examined the types of organizations that have rights protection policies. Instead of the classic normative approach to ethical issues, this study took a contextual approach to the management of rights in the workplace through human resource policies. Associations were found between (...) the organizational characteristics of size, industry, unionization, business condition, and the existence of employee and employer rights policies. Additional analyses revealed underlying dimensions in right policies and the relationship of organizational characteristics to these aspects of rights management were examined. The results are discussed in terms of understanding human resource rights management within an organizational context. (shrink)