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  1.  71
    Three Problems with Big Data and Artificial Intelligence in Medicine.Benjamin Chin-Yee & Ross Upshur - 2019 - Perspectives in Biology and Medicine 62 (2):237-256.
    We live in the Age of Big Data. In medicine, artificial intelligence and machine learning algorithms, fueled by big data, promise to change how physicians make diagnoses, determine prognoses, and develop new treatments. An exponential rise in articles on these topics is seen in the medical literature. Recent applications range from the use of deep learning neural networks to diagnose diabetic retinopathy and skin cancer from image databases, to the use of various machine learning algorithms for prognostication in cancer and (...)
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  2.  43
    Re-evaluating concepts of biological function in clinical medicine: towards a new naturalistic theory of disease.Benjamin Chin-Yee & Ross E. G. Upshur - 2017 - Theoretical Medicine and Bioethics 38 (4):245-264.
    Naturalistic theories of disease appeal to concepts of biological function, and use the notion of dysfunction as the basis of their definitions. Debates in the philosophy of biology demonstrate how attributing functions in organisms and establishing the function-dysfunction distinction is by no means straightforward. This problematization of functional ascription has undermined naturalistic theories and led some authors to abandon the concept of dysfunction, favoring instead definitions based in normative criteria or phenomenological approaches. Although this work has enhanced our understanding of (...)
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  3.  9
    Re-evaluating Concepts of Biological Function in Clinical Medicine: Towards a New Naturalistic Theory of Disease.Benjamin Chin-Yee & Ross E. G. Upshur - 2017 - Theoretical Medicine and Bioethics: Philosophy of Medical Research and Practice 38 (4):245-264.
    Naturalistic theories of disease appeal to concepts of biological function, and use the notion of dysfunction as the basis of their definitions. Debates in the philosophy of biology demonstrate how attributing functions in organisms and establishing the function-dysfunction distinction is by no means straightforward. This problematization of functional ascription has undermined naturalistic theories and led some authors to abandon the concept of dysfunction, favoring instead definitions based in normative criteria or phenomenological approaches. Although this work has enhanced our understanding of (...)
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  4.  21
    Reuniting philosophy and science to advance cancer research.Thomas Pradeu, Bertrand Daignan-Fornier, Andrew Ewald, Pierre-Luc Germain, Samir Okasha, Anya Plutynski, Sébastien Benzekry, Marta Bertolaso, Mina Bissell, Joel S. Brown, Benjamin Chin-Yee, Ian Chin-Yee, Hans Clevers, Laurent Cognet, Marie Darrason, Emmanuel Farge, Jean Feunteun, Jérôme Galon, Elodie Giroux, Sara Green, Fridolin Gross, Fanny Jaulin, Rob Knight, Ezio Laconi, Nicolas Larmonier, Carlo Maley, Alberto Mantovani, Violaine Moreau, Pierre Nassoy, Elena Rondeau, David Santamaria, Catherine M. Sawai, Andrei Seluanov, Gregory D. Sepich-Poore, Vanja Sisirak, Eric Solary, Sarah Yvonnet & Lucie Laplane - 2023 - Biological Reviews 98 (5):1668-1686.
    Cancers rely on multiple, heterogeneous processes at different scales, pertaining to many biomedical fields. Therefore, understanding cancer is necessarily an interdisciplinary task that requires placing specialised experimental and clinical research into a broader conceptual, theoretical, and methodological framework. Without such a framework, oncology will collect piecemeal results, with scant dialogue between the different scientific communities studying cancer. We argue that one important way forward in service of a more successful dialogue is through greater integration of applied sciences (experimental and clinical) (...)
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  5. Clinical judgment.Ross Upshur & Benjamin Chin-Yee - 2016 - In Miriam Solomon, Jeremy R. Simon & Harold Kincaid (eds.), The Routledge Companion to Philosophy of Medicine. Routledge.
     
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  6.  12
    COVID-19, digital health technology and the politics of the unprecedented.Benjamin Chin-Yee & Dillon Wamsley - 2021 - Big Data and Society 8 (1).
    The COVID-19 global pandemic has stretched the capacities of public health institutions and health systems around the world, opening the door to a range of technologically-driven solutions. In this article, we seek to historicize the expanding role of digital health technologies and examine the political-economic context from which they have emerged. Drawing on critical insights from science and technology studies, we maintain that the rise of digital health technologies has been catalyzed by broad shifts in global health governance that have (...)
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