39 found
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  1.  52
    Reframing Consent for Clinical Research: A Function-Based Approach.Scott Y. H. Kim, David Wendler, Kevin P. Weinfurt, Robert Silbergleit, Rebecca D. Pentz, Franklin G. Miller, Bernard Lo, Steven Joffe, Christine Grady, Sara F. Goldkind, Nir Eyal & Neal W. Dickert - 2017 - American Journal of Bioethics 17 (12):3-11.
    Although informed consent is important in clinical research, questions persist regarding when it is necessary, what it requires, and how it should be obtained. The standard view in research ethics is that the function of informed consent is to respect individual autonomy. However, consent processes are multidimensional and serve other ethical functions as well. These functions deserve particular attention when barriers to consent exist. We argue that consent serves seven ethically important and conceptually distinct functions. The first four functions pertain (...)
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  2.  29
    Resolving Ethical Dilemmas: A Guide for Clinicians.Bernard Lo - 1994 - Williams & Wilkins.
    Highlights of this edition include: / Important new material addressing federal privacy regulations, disclosure of medical errors, limits on residents'...
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  3.  17
    Behind Closed Doors: Promises and Pitfalls of Ethics Committees.Bernard Lo - forthcoming - Bioethics.
  4.  24
    The Future of Conflicts of Interest: A Call for Professional Standards.Bernard Lo - 2012 - Journal of Law, Medicine and Ethics 40 (3):441-451.
    Stricter policies regarding conflicts of interest policies will increase transparency but have limitations and unintended adverse consequences. Physicians and the medical profession should take the lead in developing policies, rather than responding to external regulations. The goal is to reduce significant risks of undue influence, while keeping the burdens and opportunity costs of policies acceptable.
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  5.  20
    The Future of Conflicts of Interest: A Call for Professional Standards.Bernard Lo - 2012 - Journal of Law, Medicine and Ethics 40 (3):441-451.
    Financial relationships between physicians and industry are widespread. Highly publicized financial relationships between physicians and industry raised disturbing questions about the trustworthiness of clinical research, practice guidelines, and clinical care decisions. Recent incidents spurred calls for stricter conflict of interest policies and led to new federal laws and NIH regulations. These stricter policies have evoked praise, concerns, and objections. Because these new federal requirements need to be interpreted and implemented, spirited discussions of conflicts of interest in medicine will continue.
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  6.  30
    The Task Force Responds.Baruch Brody, Nancy Dubler, Jeff Blustein, Arthur Caplan, Jeffrey P. Kahn, Nancy Kass, Bernard Lo, Jonathan Moreno, Jeremy Sugarman & Laurie Zoloth - 2002 - Hastings Center Report 32 (3):22-23.
  7.  24
    Resolving Ethical Issues in Stem Cell Clinical Trials: The Example of Parkinson Disease.Bernard Lo & Lindsay Parham - 2010 - Journal of Law, Medicine and Ethics 38 (2):257-266.
    Clinical trials of stem cell transplantation raise ethical issues that are intertwined with scientific and design issues, including choice of control group and intervention, background interventions, endpoints, and selection of subjects. We recommend that the review and IRB oversight of stem cell clinical trials should be strengthened. Scientific and ethics review should be integrated in order to better assess risks and potential benefits. Informed consent should be enhanced by assuring that participants comprehend key aspects of the trial. For the trial (...)
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  8.  36
    Assessing Decision-Making Capacity.Bernard Lo - 1990 - Journal of Law, Medicine and Ethics 18 (3):193-201.
  9.  10
    Resolving Ethical Issues in Stem Cell Clinical Trials: The Example of Parkinson Disease.Bernard Lo & Lindsay Parham - 2010 - Journal of Law, Medicine and Ethics 38 (2):257-266.
    Stem cells derived from pluripotent cells offer the hope of new treatments for diseases for which current therapy is inadequate. Clinical trials are essential in developing effective and safe stem cell therapies and fulfilling this promise. However, such clinical trials raise ethical issues that are more complex than those raised in clinical trials using drugs, cord blood stem cells, or adult stem cells. Several clinical trials are now being carried out with stem cells derived from pluripotent cells, and many more (...)
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  10.  22
    Assessing Decision-Making Capacity.Bernard Lo - 1990 - Journal of Law, Medicine and Ethics 18 (3):193-201.
  11.  56
    The Impact of Web 2.0 on the Doctor-Patient Relationship.Bernard Lo & Lindsay Parham - 2010 - Journal of Law, Medicine and Ethics 38 (1):17-26.
    Web 2.0 innovations may enhance informed patient decision-making, but also raise ethical concerns about inaccurate or misleading information, damage to the doctor-patient relationship, privacy and confidentiality, and health disparities. To increase the benefits and decrease the risks of these innovations, we recommend steps to help patients assess the quality of health information on the Internet; promote constructive doctor-patient communication about new information technologies; and set standards for privacy and data security in patient-controlled health records and for point-of-service advertising.
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  12.  10
    Medical Journals and Conflicts of Interest.Robert Steinbrook & Bernard Lo - 2012 - Journal of Law, Medicine and Ethics 40 (3):488-499.
    Physicians and patients rely on medical journals as trusted sources of medical information. Unfortunately, in multiple instances conflicts of interest have undermined the credibility of the medical literature.The primary sources of conflict of interest at medical journals are authors, reviewers, editors, and journals. Consider these examples.
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  13.  6
    Medical Journals and Conflicts of Interest.Robert Steinbrook & Bernard Lo - 2012 - Journal of Law, Medicine and Ethics 40 (3):488-499.
    Physicians and patients rely on medical journals as trusted sources of medical information. Unfortunately, conflicts of interest may undermine the credibility of the medical literature. Improved policies and practices at journals should address the conflicts of interest of authors, reviewers, editors, and journals. Medical journals should manage and eliminate conflicts, not just improve the disclosure of financial relationships.
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  14.  18
    Untapped Potential: IRB Guidance for the Ethical Research Use of Stored Biological Materials.Leslie E. Wolf & Bernard Lo - 2003 - IRB: Ethics & Human Research 26 (4):1-8.
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  15.  23
    Futility: Not Just a Medical Issue.Ann Alpers & Bernard Lo - 1992 - Journal of Law, Medicine and Ethics 20 (4):327-329.
  16.  11
    Legal Barriers to Implementing Recommendations for Universal, Routine Prenatal HIV Testing.Leslie E. Wolf, Bernard Lo & Lawrence O. Gostin - 2004 - Journal of Law, Medicine and Ethics 32 (1):137-147.
    Administraation of antiretroviral therapy to women during pregnancy, labor and delivery, and to infants postnatally can dramatidy reduce mother-to- child HIV transmission. However, pregnant women need to know that they are HIV-infected to take advantage of antiretroviral therapy, and many women do not know their HIV status. One-half of HIV-infected infants in the United States were bornto women who had not been tested for HIV or for whom the time of testing was not known. Although fewer than 400infants are infected (...)
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  17.  20
    Legal Barriers to Implementing Recommendations for Universal, Routine Prenatal HIV Testing.Leslie E. Wolf, Bernard Lo & Lawrence O. Gostin - 2004 - Journal of Law, Medicine and Ethics 32 (1):137-147.
    Administraation of antiretroviral therapy to women during pregnancy, labor and delivery, and to infants postnatally can dramatidy reduce mother-to- child HIV transmission. However, pregnant women need to know that they are HIV-infected to take advantage of antiretroviral therapy, and many women do not know their HIV status. One-half of HIV-infected infants in the United States were bornto women who had not been tested for HIV or for whom the time of testing was not known. Although fewer than 400infants are infected (...)
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  18.  16
    Futility: Not Just a Medical Issue.Ann Alpers & Bernard Lo - 1992 - Journal of Law, Medicine and Ethics 20 (4):327-329.
  19.  8
    Appropriate Management of Pain: Addressing the Clinical, Legal, and Regulatory Barriers.Bernard Lo & Karen H. Rothenberg - 1996 - Journal of Law, Medicine and Ethics 24 (4):285-286.
    Adequate treatment of pain is essential to alleviate suffering, yet studies show that patients with terminal or serious illness receive inadequate pain relief. In the case of terminally ill patients, adequate palliation of pain may be likely to reduce requests for physician-assisted suicide. This issue of the journal addresses barriers to effective pain relief and suggests how treatment of pain can be improved. The symposium features the Pain Relief Act, which is designed to provide practitioners who prescribe controlled substances for (...)
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  20.  6
    Appropriate Management of Pain: Addressing the Clinical, Legal, and Regulatory Barriers.Bernard Lo & Karen H. Rothenberg - 1996 - Journal of Law, Medicine and Ethics 24 (4):285-286.
    Adequate treatment of pain is essential to alleviate suffering, yet studies show that patients with terminal or serious illness receive inadequate pain relief. In the case of terminally ill patients, adequate palliation of pain may be likely to reduce requests for physician-assisted suicide. This issue of the journal addresses barriers to effective pain relief and suggests how treatment of pain can be improved. The symposium features the Pain Relief Act, which is designed to provide practitioners who prescribe controlled substances for (...)
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  21.  49
    A Middle Ground on Physician-Assisted Suicide.James A. Tulsky, Ann Alpers & Bernard Lo - 1996 - Cambridge Quarterly of Healthcare Ethics 5 (1):33.
    “[A] murder prosecution is a poor way to design an ethical and moral code for doctors,” observed the California Court of Appeal in 1983. Yet, physicians who have chosen to help terminally ill patients to commit suicide have trespassed on illegal ground. When skilled medical care fails to relieve the pain of terminally ill patients, some people believe that physicians may assist in these suicides. Others reject any kind of physician involvement. The debate on assisted suiczide and active euthanasia has (...)
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  22.  48
    The End of Therapeutic Privilege?Nicole Sirotin & Bernard Lo - 2006 - Journal of Clinical Ethics 17 (4):312.
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  23.  11
    Placebo Prescriptions Are Missed Opportunities for Doctor–Patient Communication.Yael Schenker, Alicia Fernandez & Bernard Lo - 2009 - American Journal of Bioethics 9 (12):48-50.
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  24.  19
    End‐of‐Life Care After Termination of SUPPORT.Bernard Lo - 1995 - Hastings Center Report 25 (6):6-8.
  25.  8
    Ethical Dilemmas in HIV Infection: What Have We Learned?Bernard Lo - 1992 - Journal of Law, Medicine and Ethics 20 (1-2):92-103.
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  26.  8
    Caring for Incompetent Patients: Is There a Physician on the Case?Bernard Lo - 1989 - Journal of Law, Medicine and Ethics 17 (3):214-220.
  27.  10
    Caring for Incompetent Patients: Is There a Physician on the Case?Bernard Lo - 1989 - Journal of Law, Medicine and Ethics 17 (3):214-220.
  28.  8
    Ethical Dilemmas in HIV Infection: What Have We Learned?Bernard Lo - 1992 - Journal of Law, Medicine and Ethics 20 (1-2):92-103.
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  29.  15
    Resolving Family-Clinician Disputes in the Context of Contested Definitions of Futility.Gabriel T. Bosslet, Bernard Lo & Douglas B. White - 2018 - Perspectives in Biology and Medicine 60 (3):314-318.
    We appreciate the opportunity to respond to Schneiderman and colleagues’ opinions on the recent Multiorganization Policy Statement, “An Official ATS/AACN/ACCP/ESICM/SCCM Policy Statement: Responding to Requests for Potentially Inappropriate Treatments in Intensive Care Units”. We will first point out three areas in which Schneiderman and colleagues seem to perceive a disagreement where there is none, then we will respond to their main criticisms of the Multiorganization Policy Statement. In doing so, we will point out areas in which we believe Schneiderman and (...)
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  30.  41
    Book Review: Assessing Genetic Risks: Implications for Health and Social Policy. [REVIEW]Bernard Lo - 1994 - Journal of Law, Medicine and Ethics 22 (4):343-344.
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  31.  19
    Medical Education: Yesterday's Reforms, Today's Problems. [REVIEW]Bernard Lo - 1988 - Hastings Center Report 18 (1):48.
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  32.  16
    Physician-Assisted Suicide in Context: Constitutional, Regulatory, and Professional Challenges.Bernard Lo, Karen H. Rothenberg & Michael Vasko - 1996 - Journal of Law, Medicine and Ethics 24 (3):181-182.
    Last month, a fifty-eight-year old man developed bleeding into his cheek and oozing from sites where previously he had had blood samples drawn. This bleeding was caused by disseminated intravascular coagulation, a complication of colon cancer that had spread to his liver and lungs. This complication occurred even though he was on chemotherapy for the cancer. In the hospital, he received transfusions and was administered medicine to stop the bleeding. However, his condition did not improve. He developed more bruises. When (...)
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  33.  7
    Physician-Assisted Suicide in Context: Constitutional, Regulatory, and Professional Challenges.Bernard Lo, Karen H. Rothenberg & Michael Vasko - 1996 - Journal of Law, Medicine and Ethics 24 (3):181-182.
    Last month, a fifty-eight-year old man developed bleeding into his cheek and oozing from sites where previously he had had blood samples drawn. This bleeding was caused by disseminated intravascular coagulation, a complication of colon cancer that had spread to his liver and lungs. This complication occurred even though he was on chemotherapy for the cancer. In the hospital, he received transfusions and was administered medicine to stop the bleeding. However, his condition did not improve. He developed more bruises. When (...)
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  34. Quality of Life Judgments in the Care of the Elderly.Bernard Lo - 1988 - In John F. Monagle & David C. Thomasma (eds.), Medical Ethics: A Guide for Health Professionals. Aspen Publishers. pp. 140--147.
     
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  35.  10
    Research with Ethnic and Minority Populations.Bernard Lo & N. Garan - 2008 - In Ezekiel J. Emanuel (ed.), The Oxford Textbook of Clinical Research Ethics. Oxford University Press. pp. 1--423.
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  36.  14
    The Unmasking of Medicine By Ian Kennedy, And: Philosophy in Medicine By Charles M. Culver and Bernard Gert.Bernard Lo - 1983 - Perspectives in Biology and Medicine 26 (4):676-677.
  37.  18
    The US Model for Oversight of Human Stem Cell Research.Lindsay Parham & Bernard Lo - 2010 - In John Elliott, W. Calvin Ho & Sylvia S. N. Lim (eds.), Bioethics in Singapore: The Ethical Microcosm. World Scientific. pp. 109.
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  38.  3
    A Middle Ground On Physician-Assisted Suicide.James Tulsky, Ann Alpers & Bernard Lo - 1996 - Cambridge Quarterly of Healthcare Ethics 5 (1):33-43.
    “[A] murder prosecution is a poor way to design an ethical and moral code for doctors,” observed the California Court of Appeal in 1983. Yet, physicians who have chosen to help terminally ill patients to commit suicide have trespassed on illegal ground. When skilled medical care fails to relieve the pain of terminally ill patients, some people believe that physicians may assist in these suicides. Others reject any kind of physician involvement. The debate on assisted suiczide and active euthanasia has (...)
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  39.  14
    Practicing Safer Research Using the Law to Protect the Confidentiality of Sensitive Research Data.Leslie E. Wolf & Bernard Lo - forthcoming - IRB: Ethics & Human Research.