We consider the problem of choosing the location of a public facility either (a) on a tree network or (b) in a Euclidean space. (a) (1996) characterize the class of target rules on a tree network by Pareto efficiency and population-monotonicity. Using Vohra's (1999) characterization of rules that satisfy Pareto efficiency and replacement-domination, we give a short proof of the previous characterization and show that it also holds on the domain of symmetric preferences. (b) The result obtained for model (a) (...) proves to be crucial for the analysis of the problem of choosing the location of a public facility in a Euclidean space. Our main result is the characterization of the class of coordinatewise target rules by unanimity, strategy-proofness, and either replacement-domination or population-monotonicity. (shrink)

We consider two-sided matching markets with couples. First, we extend a result by Klaus and Klijn (J Econ Theory 21: 75–106, 2005, Theorem 3.3) and show that for any weakly responsive couples market, there always exists a “double stable” matching, i.e., a matching that is stable for the couples market and for any associated singles market. Second, we show that for weakly responsive couples markets, the associated stable correspondence is (Maskin) monotonic and Nash implementable. In contrast, the correspondence that (...) assigns all double stable matchings is neither monotonic nor Nash implementable. (shrink)

“Die Gedanken sind frei,” in the words of the old song. But in Germany, thoughts are no longer free. Peter Singer, the “death ethicist,” has become a special target for activists attempting to silence bioethical debate in Germany. In the context of the trauma inflicted by National Socialism, a profound unease over issues at the end of life is accompanied by an insistence that these issues are not to be discussed.

“Die Gedanken sind frei,” in the words of the old song. But in Germany, thoughts are no longer free. Peter Singer, the “death ethicist,” has become a special target for activists attempting to silence bioethical debate in Germany. In the context of the trauma inflicted by National Socialism, a profound unease over issues at the end of life is accompanied by an insistence that these issues are not to be discussed.

Akt, a protein kinase hyperactivated in many tumors, plays a major role in both cell survival and resistance to tumor therapy. A recent study,1 along with other evidences, shows interestingly, that Akt is not a single‐function kinase, but may facilitate rather than inhibit cell death under certain conditions. This hitherto undetected function of Akt is accomplished by its ability to increase reactive oxygen species and to suppress antioxidant enzymes. The ability of Akt to down‐regulate antioxidant defenses uncovers a novel Achilles' (...) heel, which could be exploited by oxidant therapies in order to selectively eradicate tumor cells that express high levels of Akt activity. (shrink)

IntroductionSpatial navigation is a complex cognitive function that declines in older age. Finding one’s way around in familiar and new environments is crucial to live and function independently. However, the current literature illustrates the efficacy of spatial navigation interventions in rehabilitative contexts such as pathological aging and traumatic injury, but an overview of existing training studies for healthy older adults is missing. This scoping review aims to identify current evidence on existing spatial navigation interventions in healthy older adults and analyze (...) their efficacy.MethodsTo identify spatial navigation interventions and assessments and investigate their effectiveness, four electronic databases were searched. Two independent reviewers conducted a screening of title, abstract and full-texts and performed a quality assessment. Studies were eligible if published in English, the full text was accessible, at least one group of healthy older adults was included with mean age of 65 years or older, three or more spatial navigation-related training sessions were conducted and at least one spatial ability outcome was reported.ResultsTen studies were included, only healthy older adults were assessed further. Studies differed in sample size, type of training, total intervention duration, and intervention period.ConclusionThe spatial navigation abilities addressed and the measures applied to elicit intervention effects varied in quantity and methodology. Significant improvements were found for at least one spatial ability-related outcome in six of 10 interventions. Two interventions achieved a non-significant positive trend, another revealed no measurable post-training improvement, and one study did not report pre-post-differences. The results indicate that different types of spatial navigation interventions improve components of spatial abilities in healthy older adults. The existing body of research does not allow conclusions on transferability of the trained components on everyday life spatial navigation performance. Future research should focus on reproducing and extending the promising approaches of available evidence. From this, valuable insights on healthy aging could emerge.Trial RegistrationThis scoping review was preregistered at Open Science Framework. (shrink)

Although lie detection procedures have been fundamentally criticized since their inception at the beginning of the 20th century, they are still in use around the world. In addition, they have created some remarkable appeal in the context of counterterrorism policies. Thereby, the links between science and fiction in this topic are quite tight and by no means arbitrary: In the progressive narrative of the lie detection devices, there is a promise of changing society for the better, which is entangled in (...) a fictional narrative provided by many cinematic and literary examples. By drawing on the concept of “diegetic technologies” formulated by David Kirby, we want to highlight the role of science fictional narratives in the historical development and current application of lie detection procedures. We therefore aim to use this conceptual frame to analyze the role of prevention-oriented mind reading procedures, which are developed for or already used in the “war on terror” with reference to their fictional predecessors. One virulent factor has to be highlighted in this context: The fictional engagement with possible new lie detection practices is in itself creating a legitimating ground for future security technologies. (shrink)

Gibt es einen spezifisch "linken" Kitsch in Abgrenzung zu politisch "rechtem"? Dieser vernachlässigten, für das Verständnis "linken Denkens" seit der Französischen Revolution aber wichtigen Frage gehen die Beiträge dieses Bandes nach.0Gezeigt wird, dass "linkes" Denken aus ganz anderen Gründen kitschanfällig ist als sein "rechtes" Pendant, auch wenn die Pathosformeln sich mitunter frappierend ähneln. Denn während rechte Ideologien den Veränderungsdruck der Moderne kompensieren, streben linke eher danach, ihn nach dem Motto "Mehr desselben" zu überbieten. Dieses Phänomen »linker Kitsch± nimmt der Band (...) in historischer und theoretischer Hinsicht anhand von sprachlichen, bildlichen und filmischen Beispielen in den Blick, sodass es in seinem konstitutiv transmedialen Charakter zur Geltung kommt. (shrink)

This article is concerned with Klee’s belief that ‘intuition’ is indispensable to the artistic and scientific understanding of natural processes and laws of nature. Examples of his pictorial practice are discussed which derive from the as yet for the most part unpublished and little studied writings from the period at the Bauhaus. Taking the methodologically diverse literature about Klee into account, this paper tries to understand Klee’s ‘scientism’ in the cultural and theoretical context of his time.Keywords: Intuition; Genius; E. T. (...) A. Hoffmann; Wilhelm Worringer. (shrink)

Beauchamp and Childress’ definition of autonomous decision‐making includes the conditions of intentionality, understanding, and non‐control. In genetics, however, a relational conception of autonomy has been increasingly recognized. This article aims to empirically assess aspects of social influence in genetic testing decision‐making and to connect these with principlist and relational theories of autonomy. We interviewed 18 adult genetic counsellees without capacity issues considering predictive genetic testing for cancer predisposition for themselves and two counselling physicians in Switzerland. We conducted a qualitative analysis, (...) building on a grounded theory study about predictive genetic testing decision‐making. We found that some participants agreed to predictive genetic testing predominantly because relatives wanted them to do it, with some even acting contrary to their own convictions. Others, in contrast, based their decision on purely individualistic reasons but expressed difficulties in explaining their decision to their social environment. Healthcare professionals had a critical influence on decision‐making in many cases without being manipulative, as perceived by counsellees. Still, cases of coercion and social pressure occurred within social relationships. In conclusion, predictive genetic testing decision‐making includes relational and individualistic aspects, and both are compatible with autonomous decision‐making. While the principlist and relational notions of autonomy compete on a theoretical level, they are two sides of the same coin when used as analytical lenses for genetic testing decision‐making. Social acceptance of refusal of testing should be improved to mitigate social pressure. Individuals should be encouraged to decide for themselves how much their social environment influences their decision regarding predictive genetic testing. (shrink)

The aim of this book is to understand and critically appraise science-based transgression dynamics in their whole complexity. It includes contributions from experts with different disciplinary backgrounds, such as philosophy, history and sociology. Thus, it is in itself an example of boundary transgression. Scientific disciplines and their objects have tended to be seen as permanent and distinct. However, science is better conceived as an activity that constantly surpasses, erases and rebuilds all kinds of boundaries, either disciplinary, socio-ethical or ecological. This (...) transgressive capacity, a characteristic trait of science and its applications, defines us as "knowledge societies." However, scientific and technological developments are also sources of serious environmental and social concerns. Contents Disciplinary Transgression of Boundaries - Extra-Disciplinary Transgression of Boundaries - Radical Transgression of Boundaries Target Groups Scientists and students of philosophy, sociology, history of science, and interdisciplinary fields such as technology assessment, sustainable development, science and technology studies - Practitioners in research management Editors Bettina-Johanna Krings (MA in sociology, political science and anthropology; PhD in sociology) is head of the research department "Knowledge Society and Knowledge Policy" at the Institute for Technology Assessment and Systems Analysis (ITAS) at the Karlsruhe Institute of Technology (KIT). Hannot Rodríguez (PhD in philosophy) is Assistant Professor at the Department of Philosophy of the University of the Basque Country UPV/EHU. Anna Schleisiek (Dipl.-Soz.) is doing research on the role of economic principles in the scientific practice of research teams for her PhD project in sociology. <. (shrink)

Der Fokus auf die Sprache bestimmte die Philosophie des 20. Jahrhunderts, die sowohl die Dekonstruktion der Metaphysik als auch den Tod des Subjekts verkündete. Der Psychoanalytiker Jacques Lacan führte das Subjekt des Begehrens wieder in den philosophischen Diskurs ein und entwickelte aus der Struktur der Sprache eine neue, symbolische Logik des Unbewussten. Die Logik des Signifikanten, deren Geschichte diese Arbeit nachzeichnet, um sie zu transzendieren, stellt die Frage nach der Dialektik von Signifikant und Begriff, Sprache und Logik, Bewusstem und Unbewusstem, (...) Ich und Subjekt, Gesetz und Begehren, Denken und Sein. Durch die Funktionen der Metonymie, der Metapher und des Stepppunktes sowie über das Schema der vier Diskurse werden die Tropen der traditionellen philosophischen Logik - Begriff, Urteil und Schluss - neu interpretiert. Das Peirce'sche Konzept der Abduktion ermöglicht es, sowohl den Borromäischen Knoten Lacans - Imaginäres, Symbolisches und Reales - wie auch die transzendentale Dialektik und Ontologie der Moderne, die auf Kants und Hegels Revolutionen der Denkungsart zurückgehen, schlusslogisch zu begründen. (shrink)

Diese komparatistische Monographie stellt zentrale Kategorien und Theorien der Literaturwissenschaft dar. Sie synthetisiert und bewertet den Stand der Forschung und unterwirft viele Dogmen der neueren Forschung einer kritischen Analyse. Resultat ist eine Reformulierung des theoretischen Kernbestandes der Literaturwissenschaft für die zentralen Kategorien Interpretation, Fiktion, Performativität, Intertextualität, Gattung, Epoche. Der Band richtet sich an alle Wissenschaften, die mit Texten als Erkenntnisobjekten umgehen; neben der Literaturwissenschaft sind also auch die Theaterwissenschaft, die Sprachwissenschaft, die Sprachphilosophie, die Kunstwissenschaft, die Geschichtswissenschaft sowie Theologie und Jurisprudenz (...) angesprochen. (shrink)

Originally presented as the author's thesis (doctoral - Leipzig) under the title: Seinsvergessenheit im Narrativismus. Zur Bedeutung sprachlicher Tiefenstrukturen im Geschichtsdenken von...

​Für die Wahrnehmung von Politik und die Beteiligung am politischen Leben einer Gesellschaft ist politisches Wissen notwendig. Der Band bündelt aktuelle Studien zur Bedeutung, zur Messung sowie zu den Bestimmungsfaktoren und Konsequenzen des politischen Wissens. Die Beiträge geben erste Antworten auf drängende Fragen und weisen auf Lücken in der Forschung zum politischen Wissen in Deutschland hin.

Is Plato’s philosophy still relevant for current issues in politics and political science? In order to answer this question, the contributions to this volume endeavour to re-read the Platonic dialogues and to interpret them in terms of textual hermeneutics on the one hand. On the other hand, they refer to Plato from a systematic point of view and apply his philosophy, in particular the method of Socratic dialogue, to discussions on contemporary political issues. The volume is dedicated to Barbara Zehnpfennig, (...) whose works aim at making Socratic–Platonic philosophy fruitful for the present on the basis of a new interpretation of Plato’s philosophy. With contributions by Anke Adamik, Sarah Al-Taher, Viktoria Bachmann, Philip Breuer, Johanna Falk-Seifert, Bettina Fröhlich, Benjamin A. Hahn, Hendrik Hansen, Thomas Haslböck, Raul Heimann, Johannes Frank Hoerlin, Vanessa Jansche, Peter Kainz, Christina Kast, Eva-Maria Kaufmann, Ulrich Kühn, Laura Martena, Julian Obenauer, Victor Peneff und Thomas Wimmer. (shrink)

Was ist Wurde? Konnen auch nichtmenschliche Tiere Wurde haben? Bettina Huber geht diesen Fragen nach, indem sie sich mit verschiedenen Auffassungen von Wurde befasst und davon ausgehend genauer auf das Verstandnis von Wurde als einer Haltung eingeht: Uber Wurde als Haltung zu verfugen bedeutet, mit dem eigenen Selbstbild in Ubereinstimmung zu leben. Die Autorin zeigt, inwiefern bestimmte nichtmenschliche Tiere die notwendigen Fahigkeiten besitzen, um ein Selbstbild zu entwickeln und damit ubereinzustimmen. Anschliessend beschaftigt sie sich mit den Bedingungen, die fur (...) ein Leben in Wurde erfullt sein mussen. Am Ende geht es um ein konkretes Beispiel, namlich warum Grossaquarien Delfinen ein Leben in Wurde nicht ermoglichen konnen - und in bestimmten Fallen eine Wurdeverletzung oder gar eine Demutigung vorliegt. (shrink)

Goal-setting theory states that challenging, specific, and concrete goals (i.e., subordinate goals) are powerful motivators and boost performance in goal pursuit more than vague or abstract goals (i.e., superordinate goals). Goal-setting theory predominantly focuses on single, short-term goals and less on broad, long-term challenges. This review article extends goal-setting theory and argues that superordinate goals also fulfill a crucial role in motivating behavior, particularly when addressing broad, long-term challenges. The purpose of this article is to show theoretically that people pursue (...) long-term goals more successfully when they focus on subordinate and superordinate goals simultaneously than when they focus on either subordinate or superordinate goals alone. (shrink)

Die globalen Veränderungen fordern unser Wissen über die Welt und über uns selbst heraus. Der Klimawandel, die globale Covid-19-Pandemie und Konflikte um die Bedeutung wissenschaftlicher Erkenntnisse führen uns unweigerlich zu einer Vielzahl komplexer philosophischer Fragen. Dabei rücken verstärkt Themen der theoretischen Philosophie in den Vordergrund: Was ist eigentlich Wissen? Auf welche Informationen können wir uns verlassen? Ist die Wahrheit relativ? Was macht ExpertInnen aus? Was ist gute wissenschaftliche Praxis? Was bedeutet 'evidenzbasiert'? Welchen sozialen und globalen Einflüssen ist unser Wissenserwerb ausgesetzt? (...) In der Ausbildung von Philosophie- und Ethikstudierenden gibt es oft eine große Scheu, Disziplinen wie Erkenntnistheorie und Wissenschaftsphilosophie zu erlernen und zu unterrichten. Zu abstrakt und lebensweltlich irrelevant, sagen viele. Dieses Buch soll diese Berührungsängste beseitigen helfen, indem die theoretischen Grundlagen auf die Probleme der Gegenwart angewendet und mit vielseitigen Methoden erschlossen werden. Zwei Ziele stehen im Vordergrund: Zum einen soll deutlich werden, dass die Beschäftigung mit theoretischer Philosophie für das persönliche und das gesellschaftliche Zusammenleben von zentraler Bedeutung ist. Zum anderen zeigen eine Reihe didaktischer Tools, wie man Lernende dabei aktiv in den Lernprozess miteinbezieht. (shrink)

Music in the Flesh reimagines the lived experiences of music-making subjects (composers, musicians, listeners) in the long European seventeenth century. There are countless historical testimonies of the powerful effects of music upon early-modern bodies, described as moving, ravishing, painful, dangerous, curative, miraculous, and encompassing "the circulation of the humors, purification of the blood, dilation of the vessels and pores. In asking what this all meant at the time, the author considers musical scores and their surrounding texts as "somatic scripts" that (...) afford a range of somatic actions and reactions and can give us a glimpse into the historical embodied experience of organized sound. Starting from the Lutheran hymns and their accompanying intellectual traditions and ritual practices in German-speaking lands, the book moves with ease across repertories and regions, sacred and vernacular musics, domestic and public settings in order to sketch a "physiology of music" that is as historically illuminating as it is relevant for present-day performing practices and that sheds unprecedented light on how subjectivity was embodied through sound in early-modern Europe. (shrink)

This article explores how historians of emotions and historians of the senses can collaborate to write a history of emotional experience that takes seriously the corporeality of emotions. It invest...

Attention is automatically allocated to stimuli that are opposite in valence to the current motivational focus (Rothermund, 2003; Rothermund, Voss, & Wentura, 2008). We tested whether this incongruency effect is due to affective–motivational counter-regulation or to an increased salience of stimuli that mismatch with cognitively activated information. Affective processing biases were assessed with a search task in which participants had to detect the spatial position at which a positive or negative stimulus was presented. In the motivational condition, positive or negative (...) affective–motivational states were induced by performance feedback after each trial. In the cognitive activation condition, participants memorised the word “good” or “bad” during the search task. The affective incongruency effect was replicated in the motivational condition, whereas an affective congruency effect obtained in the cognitive activation condition. These findings support an explanation of affective incongruency effects in terms of automatic counter-regulation that is motivational in nature. (shrink)

Platons,Gorgias' hat eine höchst unterschiedliche Rezeption erfahren. In der Forschung gilt er als einer der schwierigsten Texte Platons. Dies ist vor allem der Fülle an Themen, die verhandelt werden, geschuldet. Sokrates spricht mit seinen drei Gesprächspartnern - mehr als in vielen anderen Dialogen Platons - über Rhetorik, Gerechtigkeit, Macht, Handlungsmotive, das glückliche und gelungene Leben, am Schluss findet sich ein Mythos über ein Seelengericht. Die scheinbare Unvereinbarkeit der verschiedenen Textelemente hat dazu geführt, dass der,Gorgias' als Vorstudie zur,Politeia' oder als Zeugnis (...) persönlicher Enttäuschung eingeschätzt wurde. In der Antike wurde der Dialog, fern solcher Kritik, viel rezipiert und kommentiert, insbesondere als Teil des neuplatonischen Lektüre- und Schulkanons. Überliefert ist aus dieser reichen Beschäftigung nur der Kommentar Olympiodors, dessen umfassende Deutung des Dialogs in dieser Studie modernen Deutungen gegenübergestellt wird. (shrink)

Die Philosophiedidaktik ist eine herausfordernde Disziplin. In ihrer Aufgabe als Vermittlungs- und Reflexionswissenschaft muss sie Entwicklungen der aktuellen Philosophie berücksichtigen, auf die komplexen Veränderungen unserer Lebenswelt reagieren, die Herausforderungen des Lernorts Schule ernst nehmen und die Erkenntnisse wesentlicher Bezugsdisziplinen einbeziehen. Diese Vernetzungsaufgabe verlangt nach systematischen philosophiedidaktischen Untersuchungen für die Lehrkräfteausbildung. Ziel dieses Bandes ist die Analyse und Diskussion der philosophischen, fachdidaktischen und bildungstheoretischen Fragestellungen einer Reihe komplexer Herausforderungen, die für die Ausbildung an der Hochschule, im Referendariat sowie in der Fort- (...) und Weiterbildung wirksam werden: Welche Rolle kann und soll philosophische Bildung in inter- und transdisziplinären Bezügen spielen, wie z.B. bei der Bildung für nachhaltige Entwicklung oder in einem Bildungslabor? Wie kann und sollte Philosophieren mit Kindern praktiziert werden? Wie kann und sollte mit der Forderung nach Inklusion umgegangen werden? Ist problemorientierter Unterricht der Goldstandard philosophischen Unterrichtens oder nicht? Auf diese und weitere Fragen geben die Beiträge der Autor*innen Antworten und Lösungsvorschläge, in denen alte und neue Kontroversen sichtbar werden. Der Band versteht sich als Beitrag zu lebendigen Grundsatzdiskursen, die ein Fundament liefern für die Entwicklung eines zeitgemäßen Philosophie- und Ethikunterrichts. (shrink)

The representation of history continues to evolve in the domain of museum exhibitions. This evolution is informed in part by the creation of new display methods—many of which depart from the traditional conventions used to achieve the “museum effect”—in part by an increased attention to the museum–visitor relationship. In this context the ethical force of bearing witness, at times a crucial aspect of the museum experience, has emerged as a particularly compelling issue. In seeking to represent and address atrocity, injustice, (...) and the abrogation of human rights, museums have the potential to become “sites of conscience” and to encourage “historical consciousness.” Through a series of three exhibitions devoted to slavery, the New-York Historical Society demonstrated how such sites can be constructed and how objects can be deployed to represent extreme or “limit cases.” In this review/essay I investigate and interrogate these exhibitions, looking closely at the use of objects as a source of “indirect testimony” and at the “dialogical situation” that might arise in an encounter among objects, exhibit narratives, and visitors. Thinking in terms of point of view, I look at the variety of rhetorical platforms from which objects speak in these exhibitions; thinking in terms of syntax, I look at the effects of ordering and of the radical juxtaposition of objects; thinking in terms of irony, I look at the provocations of double-voiced narratives and at how objects are used to support those historical sentences. (shrink)

In this book, linguists and philosophers combine to offer a unique insight not only into Grice's contribution to philosophy of language, but on his theories of natural and non-natural meaning, implicatures and the semantic-pragmatic distinction.

This chapter describes the phenomenology of the political world. Phenomenology must get underway with an analysis of the political world. The chapter evaluates more precisely the relation between the concept of world or worldliness and the openness of the political. Using the term ‘political world’ is preferred to utilising the traditional terms because it is less burdened by prejudice. The guiding impulse towards the clarification of the Sache of political philosophy as political world stems from Hannah Arendt, who does not (...) make use of the phenomenological conception of ‘horizon’. Science's confidence that it can attain a knowledge free of all horizonal plurality is among the most fundamental prejudices that phenomenology endeavours to overcome. Phenomenology is the decided present renewal of the most ancient idea of epistêmê. (shrink)

The achievement of unity and perfection in human action begins with a struggle for these ideals in human thought. Dr. Klaus Vondung in his collection of essays that span four decades explores examples of this in different fields of human inquiry: striving for harmonious existential unity of talents and morals, intellect and emotion; seeking to make natural sciences consonant with the humanities and thereby moving toward a more universal, "perfect" science; and establishing unity in political structures and cultivating in (...) this unity a homogenous society. Vondung has given special devotion to National Socialism as a context wherein he revisits its perverted motivation and the consequences of this despite noble ideals. Particular focus in following the thread of unity and perfection in human intellectual and practical ambitions ultimately hones in on the combination of religion and politics. Vondung in these essays unpacks the ways in which this continues to fascinate and disturb us, and in his expertise he uses National Socialism to connect this pursuit of unity and perfection to what he calls one of the signature marks of modernity--namely, secular apocalypticism. This claim stands in opposition to Eric Voegelin's remark that Gnosticism, rather, is "the nature of modernity." Vondung, who studied and wrote his dissertation under Voegelin, grapples with the contrast of these positions. Vondung is willing to challenge Voegelin, but ultimately his treatment of the latter bears the quality of tribute to this great scholar. Vondung also explores the points of contact between apocalypticism and Hermetic speculation. Despite the independence of the religious and philosophical doctrines of Hermeticism, there are parallels to be found. Apocalypticism and Hermeticism originated in antiquity and yet each represents a tradition that still holds footing today. Vondung furthermore leads the reader to see the project of salvation found in both even as each operates with a different scope. This collection of essays centers itself on a perspective of the human pursuit of unity and perfection, directly or indirectly, as objectives of intellectual endeavors, existential ideals, as social or political outcomes, and in the case of National Socialism even as perverse aberrations. Vondung's particular treatment of Voegelin's work likewise establishes what the former identifies as a stand-out question of this study: Does the search of order in history show us the unity of the history of humankind? (shrink)

The term ‘locked-in’ syndrome (LIS) describes a medical condition in which persons concerned are severely paralyzed and at the same time fully conscious and awake. The resulting anarthria makes it impossible for these patients to naturally communicate, which results in diagnostic as well as serious practical and ethical problems. Therefore, developing alternative, muscle-independent communication means is of prime importance. Such communication means can be realized via brain–computer interfaces (BCIs) circumventing the muscular system by using brain signals associated with preserved cognitive, (...) sensory, and emotional brain functions. Primarily, BCIs based on electrophysiological measures have been developed and applied with remarkable success. Recently, also blood flow–based neuroimaging methods, such as functional magnetic resonance imaging (fMRI) and functional near-infrared spectroscopy (fNIRS), have been explored in this context. After reviewing recent literature on the development of especially hemodynamically based BCIs, we introduce a highly reliable and easy-to-apply communication procedure that enables untrained participants to motor-independently and relatively effortlessly answer multiple-choice questions based on intentionally generated single-trial fMRI signals that can be decoded online. Our technique takes advantage of the participants’ capability to voluntarily influence certain spatio-temporal aspects of the blood oxygenation level–dependent (BOLD) signal: source location (by using different mental tasks), signal onset and offset. We show that healthy participants are capable of hemodynamically encoding at least four distinct information units on a single-trial level without extensive pretraining and with little effort. Moreover, realtime data analysis based on simple multi-filter correlations allows for automated answer decoding with a high accuracy (94.9%) demonstrating the robustness of the presented method.. (shrink)